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We investigate conductance and conductance fluctuations of two transmembrane proteins, bacteriorhodopsin and proteorhodopsin, belonging to the family of protein light receptors. These proteins are widely diffused in aqueous environments,…

软凝聚态物质 · 物理学 2013-05-27 E. Alfinito , J. Pousset , L. Reggiani

When moving from native to light activated bacteriorhodopsin, modification of charge transport consisting of an increase of conductance is correlated to the protein conformational change. A theoretical model based on a map of the protein…

定量方法 · 定量生物学 2011-02-17 Eleonora Alfinito , Lino Reggiani

Recently, a growing interest has been addressed to the electrical properties of bacteriorhodopsin (bR), a protein belonging to the transmembrane protein family. To take into account the structure-dependent nature of the current, in a…

软凝聚态物质 · 物理学 2015-03-06 E. Alfinito , L. Reggiani

The increasing interest in photoactivated proteins as natural replacement of standard inorganic materials in photocells drives to the compared analysis of bacteriorhodopsin and proteorhodopsin, two widely diffused proteins belonging to the…

生物物理 · 物理学 2015-06-16 E Alfinito , J Pousset , L Reggiani , K Lee

Current voltage (I-V) characteristics in proteins can be sensitive to conformational change induced by an external stimulus (photon, odour, etc.). This sensitivity can be used in medical and industrial applications besides shedding new…

软凝聚态物质 · 物理学 2015-05-28 Eleonora Alfinito , Jean-Francois Millithaler , Lino Reggiani

We report on charge transport and current fluctuations in a single bacteriorhodpsin protein in a wide range of applied voltages covering direct and injection tunnelling regimes. The satisfactory agreement between theory and available…

介观与纳米尺度物理 · 物理学 2011-02-17 J. -F. Millithaler , E. Alfinito , L. Reggiani

The electrical properties of a set of seven-helix transmembrane proteins, whose space arrangement (3D structure) is known, are investigated by using regular arrays of the amino acids. These structures, specifically cubes, have topological…

软凝聚态物质 · 物理学 2016-06-02 Eleonora Alfinito , Lino Reggiani

One of the main trend in to date research and development is the miniaturization of electronic devices. In this perspective, integrated nanodevices based on proteins or biomolecules are attracting a major interest. In fact, it has been…

定量方法 · 定量生物学 2015-06-26 E. Alfinito , C. Pennetta , L. Reggiani

We report on electrical properties of the two sensing proteins: bacteriorhodopsin and rat olfactory receptor OR-I7. As relevant transport parameters we consider the small-signal impedance spectrum and the static current-voltage…

介观与纳米尺度物理 · 物理学 2015-05-27 E. Alfinito , L. Reggiani

The interaction of light with photosynthetic proteins is an extremely efficient process and has been thoroughly investigated. However, exploring light-matter interactions in hybrid nano-solid-photosynthetic proteins is a relatively new and…

生物物理 · 物理学 2024-11-20 Itai Carmeli , Chanoch Carmeli

How molecules convert light energy to perform a specific transformation is a fundamental question in photophysics. Ultrafast spectroscopy reveals the kinetics associated with electronic energy flow, but little is known about how absorbed…

The mini-review gives special attention to holistic approach and mechanisms of processes. The physical and chemical frames and background for visual perception and signalling are discussed. Perception of photons by retinal rod cells is…

其他定量生物学 · 定量生物学 2013-07-01 Vadim Volkov

New science and new technology need new materials and new concepts. In this respect, biological matter can play a primary role because it is a material with interesting and innovative features that have found several applications in…

应用物理 · 物理学 2022-01-26 E. Alfinito , R. Cataldo , L. Reggiani

Photoactive proteins absorb light and undergo structural changes that enable them to perform essential biological functions. These proteins are critical for understanding light-induced biological processes, making them important in…

化学物理 · 物理学 2025-03-28 Sylwia Czach , Jakub Rydzewski , Wiesław Nowak

We present a palette of brightly fluorescent genetically encoded voltage indicators (GEVIs) with excitation and emission peaks spanning the visible spectrum, sensitivities from 6 - 10% Delta F/F per 100 mV, and half-maximal response times…

Biological systems transduce signals from their surroundings in numerous ways. This paper introduces a communication system using the light-gated ion channel Channelrhodopsin-2 (ChR2), which causes an ion current to flow in response to…

信息论 · 计算机科学 2024-11-11 Taha Sajjad , Andrew W. Eckford

The need of new diagnostic methods satisfying, as an early detection, a low invasive procedure and a cost-efficient value, is orienting the technological research toward the use of bio-integrated devices, in particular bio-sensors. The set…

生物大分子 · 定量生物学 2015-06-18 E. Alfinito , L. Reggiani

Nucleic acids and proteins are not only biologically important polymers: They have recently been recognized as novel functional materials surpassing in many aspects the conventional ones. Although Herculean efforts have been undertaken to…

软凝聚态物质 · 物理学 2010-06-17 Waleed Shinwari , Jamal Deen , Evgeni Starikov , Gianaurelio Cuniberti

It is shown that a small subset of modes which are likely to be involved in protein functional motions of large amplitude can be determined by retaining the most robust normal modes obtained using different protein models. This result…

生物大分子 · 定量生物学 2007-05-23 Samuel Nicolay , Yves-Henri Sanejouand

Biosensors are frequently used nowadays for the sake of their attractive capabilities. Because of their high accuracy and precision, they are more and more used in the medical sector. Natural receptors are mostly used, but their use have…

细胞行为 · 定量生物学 2021-02-17 Juul Goossens , Gilles Oudebrouckx , Seppe Bormans , Thijs Vandenryt , Ronald Thoelen
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