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Recent advances in engineering technologies have enabled the collection of a large number of longitudinal features. This wealth of information presents unique opportunities for researchers to investigate the complex nature of diseases and…

统计方法学 · 统计学 2023-11-27 Zihang Lu , Noirrit Kiran Chandra

Mixture models are widely used in modeling heterogeneous data populations. A standard approach of mixture modeling assumes that the mixture component takes a parametric kernel form. In many applications, making parametric assumptions on the…

统计方法学 · 统计学 2026-03-06 Yilei Zhang , Yun Wei , Aritra Guha , XuanLong Nguyen

Multivariate data that combine binary, categorical, count and continuous outcomes are common in the social and health sciences. We propose a semiparametric Bayesian latent variable model for multivariate data of arbitrary type that does not…

应用统计 · 统计学 2014-01-14 Jonathan Gruhl , Elena A. Erosheva , Paul K. Crane

We propose a non-linear, Bayesian non-parametric latent variable model where the latent space is assumed to be sparse and infinite dimensional a priori using an Indian buffet process prior. A posteriori, the number of instantiated…

机器学习 · 统计学 2022-05-30 Michael Minyi Zhang

The therapeutic working alliance is a critical predictor of psychotherapy success. Traditionally, working alliance assessment relies on questionnaires completed by both therapists and patients. In this paper, we present COMPASS, a novel…

计算与语言 · 计算机科学 2025-08-12 Baihan Lin , Djallel Bouneffouf , Yulia Landa , Rachel Jespersen , Cheryl Corcoran , Guillermo Cecchi

Motivated by genetic association studies of pleiotropy, we propose here a Bayesian latent variable approach to jointly study multiple outcomes or phenotypes. The proposed method models both continuous and binary phenotypes, and it accounts…

应用统计 · 统计学 2012-11-08 Lizhen Xu , Radu V. Craiu , Lei Sun

Motivation: Spontaneous adverse event reports have a high potential for detecting adverse drug reactions. However, due to their dimension, exploring such databases requires statistical methods. In this context, disproportionality measures…

应用统计 · 统计学 2015-06-19 Matthieu Marbac , Pascale Tubert-Bitter , Mohammed Sedki

We present generalized additive latent and mixed models (GALAMMs) for analysis of clustered data with responses and latent variables depending smoothly on observed variables. A scalable maximum likelihood estimation algorithm is proposed,…

统计方法学 · 统计学 2023-03-29 Øystein Sørensen , Anders M. Fjell , Kristine B. Walhovd

Perceptual multistability, observed across species and sensory modalities, offers valuable insights into numerous cognitive functions and dysfunctions. For instance, differences in temporal dynamics and information integration during…

神经元与认知 · 定量生物学 2025-06-24 Shervin Safavi , Danaé Rolland , Philipp Sterzer , Renaud Jardri , Pantelis Leptourgos

This work proposes a new algorithm for automated and simultaneous phenotyping of multiple co-occurring medical conditions, also referred as comorbidities, using clinical notes from the electronic health records (EHRs). A basic latent factor…

机器学习 · 统计学 2016-09-21 Shalmali Joshi , Suriya Gunasekar , David Sontag , Joydeep Ghosh

Performing causal inference in observational studies requires we assume confounding variables are correctly adjusted for. G-computation methods are often used in these scenarios, with several recent proposals using Bayesian versions of…

统计方法学 · 统计学 2021-10-25 Daniel Daly-Grafstein , Paul Gustafson

Several approaches have been proposed in the literature for clustering multivariate ordinal data. These methods typically treat missing values as absent information, rather than recognizing them as valuable for profiling population…

统计方法学 · 统计学 2024-11-05 Alice Giampino , Antonio Canale , Bernardo Nipoti

Bayesian nonparametric mixtures and random partition models are powerful tools for probabilistic clustering. However, standard independent mixture models can be restrictive in some applications such as inference on cell lineage due to the…

统计方法学 · 统计学 2025-07-15 Giovanni Rebaudo , Peter Mueller

Metabolomic based approaches have gained much attention in recent years due to their promising potential to deliver objective tools for assessment of food intake. In particular, multiple biomarkers have emerged for single foods. However,…

统计方法学 · 统计学 2021-05-10 Silvia D'Angelo , Lorraine Brennan , Isobel Claire Gormley

Sparse latent multi-factor models have been used in many exploratory and predictive problems with high-dimensional multivariate observations. Because of concerns with identifiability, the latent factors are almost always assumed to be…

应用统计 · 统计学 2013-12-09 Vinicius Diniz Mayrink , Joseph Edward Lucas

Generative Bayesian Filtering (GBF) provides a powerful and flexible framework for performing posterior inference in complex nonlinear and non-Gaussian state-space models. Our approach extends Generative Bayesian Computation (GBC) to…

统计方法学 · 统计学 2025-11-07 Edoardo Marcelli , Sean O'Hagan , Veronika Rockova

Correlations between anomalous activity patterns can yield pertinent information about complex social processes: a significant deviation from normal behavior, exhibited simultaneously by multiple pairs of actors, provides evidence for some…

人工智能 · 计算机科学 2013-11-19 Aaron Schein , Juston Moore , Hanna Wallach

We propose a Bayesian latent variable model to estimate covariate-assisted dependence structures across multiple modalities of multivariate data that may be observed asynchronously. This setting commonly arises in longitudinal biomedical…

统计方法学 · 统计学 2026-05-27 Kun Qian , Hyung G. Park

We present the Wright-Fisher Indian buffet process (WF-IBP), a probabilistic model for time-dependent data assumed to have been generated by an unknown number of latent features. This model is suitable as a prior in Bayesian nonparametric…

机器学习 · 统计学 2016-11-23 Valerio Perrone , Paul A. Jenkins , Dario Spano , Yee Whye Teh

Discrete data are abundant and often arise as counts or rounded data. These data commonly exhibit complex distributional features such as zero-inflation, over-/under-dispersion, boundedness, and heaping, which render many parametric models…

统计方法学 · 统计学 2023-02-27 Daniel R. Kowal , Bohan Wu