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This article shows how to fit reticulate finite and infinite sites sequence spectra to aligned data from five modern human genomes (San, Yoruba, French, Han and Papuan) plus two archaic humans (Denisovan and Neanderthal), to better infer…

种群与进化 · 定量生物学 2011-12-30 Peter J. Waddell , Jorge Ramos , Xi Tan

Introgressions from Neanderthals and Denisovans were detected in modern humans. Introgressions from other archaic hominins were also implicated, however, identification of which poses a great technical challenge. Here, we introduced an…

种群与进化 · 定量生物学 2014-05-01 Ya Hu , Yi Wang , Qiliang Ding , Yungang He , Minxian Wang , Jiucun Wang , Shuhua Xu , Li Jin

Recent studies have shown that hybridization between modern and archaic humans was commonplace in the history of our species. After admixture, some individuals with admixed autosomes carried the modern Homo Sapiens uniparental DNAs, while…

其他定量生物学 · 定量生物学 2020-03-31 Hongyao Chen , Shi Huang

We will give a simple, unified, possible explanation of several debated genetic issues on today's humans, Neandertals and Denisovans. In particular it is shown by means of a simple mathematical model why there is little genetic variation in…

种群与进化 · 定量生物学 2021-07-27 Per H. Enflo , Gustavo A. Muñoz-Fernández , Juan B. Seoane-Sepúlveda

Although there has been much interest in estimating divergence and admixture from genomic data, it has proven difficult to distinguish gene flow after divergence from alternative histories involving structure in the ancestral population.…

种群与进化 · 定量生物学 2013-08-01 Konrad Lohse , Laurent A. F. Frantz

Chromosomal rearrangements, which shuffle DNA throughout the genome, are an important source of divergence across taxa. Using a paired-end read approach with Illumina sequence data for archaic humans, I identify changes in genome structure…

基因组学 · 定量生物学 2015-10-07 Rebekah L. Rogers

Comparisons of DNA sequences between Neandertals and present-day humans have shown that Neandertals share more genetic variants with non-Africans than with Africans. This could be due to interbreeding between Neandertals and modern humans…

种群与进化 · 定量生物学 2012-08-13 Sriram Sankararaman , Nick Patterson , Heng Li , Svante Pääbo , David Reich

Estimating the phylogeny of the genus Homo is entering a new phase of vastly improved data and methodology. There is increasing evidence of 6 to 10 competing species/lineages at any point in the last half million years, making the…

种群与进化 · 定量生物学 2017-01-02 Peter J. Waddell

Considering the recent experimental discovery of Green et al that present day non-Africans have 1 to 4% of their nuclear DNA of Neanderthal origin, we propose here a model which is able to quantify the interbreeding events between Africans…

种群与进化 · 定量生物学 2011-06-06 Armando G. M. Neves , Maurizio Serva

We consider here an extension of a previous work by Neves and Serva, still unpublished, which estimates the amount of interbreeding between anatomically modern Africans and Neandertals necessary for explaining the experimental fact that 1…

种群与进化 · 定量生物学 2011-05-31 Armando G. M. Neves

This article shows how 3D geometric morphometric data can be analyzed using newly developed distance-based evolutionary tree inference methods, with extensions to planar graphs. Application of these methods to 3D representations of the…

种群与进化 · 定量生物学 2015-01-05 Peter J. Waddell

We consider a large population of asexually reproducing individuals in absence of selective pressure. The population size is maintained constant by the environment. We find out that distances between individuals (time from the last common…

统计力学 · 物理学 2007-05-23 Maurizio Serva

Analyses of a set of 47 fossil and 4 modern skulls using phylogenetic geometric morphometric methods corroborate and refine earlier results. These include evidence that the African Iwo Eleru skull, only about 12,000 years old, indeed…

种群与进化 · 定量生物学 2015-12-31 Peter J. Waddell

Genetic association data from national biobanks and large-scale association studies have provided new prospects for understanding the genetic evolution of complex traits and diseases in humans. In turn, genomes from ancient human…

种群与进化 · 定量生物学 2021-08-06 Evan K. Irving-Pease , Rasa Muktupavela , Michael Dannemann , Fernando Racimo

Recent genetic studies and whole-genome sequencing projects have greatly improved our understanding of human variation and clinically actionable genetic information. Smaller ethnic populations, however, remain underrepresented in both…

The discovery of Paranthropus deyiremeda in 3.3-3.5 million year old fossil sites in Afar, together with 30% of the gorilla genome showing lineage sorting between humans and chimpanzees, and a NUMT ("nuclear mitochondrial DNA segment") on…

其他定量生物学 · 定量生物学 2018-10-12 Johan Nygren

Non-African populations have experienced major bottlenecks in the time since their split from West Africans, which has led to the hypothesis that natural selection to remove weakly deleterious mutations may have been less effective in…

种群与进化 · 定量生物学 2014-02-21 Ron Do , Daniel Balick , Heng Li , Ivan Adzhubei , Shamil Sunyaev , David Reich

On the base of advantages in gene geography and anthropophenetics the phenogeographical method for anthropological research is initiated and experienced using dental data. Statistical and cartographical analyses are provided for 498 living…

种群与进化 · 定量生物学 2011-07-19 Vera F. Kashibadze , Olga G. Nasonova , Dmitry S. Nasonov

The discovery of Paranthropus deyiremeda in 3.3-3.5 million year old fossil sites in Afar (Haile-Selassie, 2015), together with 30% of the gorilla genome showing lineage sorting between humans and chimpanzees (Scally, 2012), and a NUMT…

种群与进化 · 定量生物学 2018-08-22 Johan Nygren

Recent advances in high-throughput genomics technologies have resulted in the sequencing of large numbers of (near) complete genomes. These genome sequences are being mined for important functional elements, such as genes. They are also…

基因组学 · 定量生物学 2007-05-23 Lior Pachter
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