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Understanding why we age is a long-lived open problem in evolutionary biology. Aging is prejudicial to the individual and evolutionary forces should prevent it, but many species show signs of senescence as individuals age. Here, I will…

种群与进化 · 定量生物学 2012-01-24 André C. R. Martins

The network concept is increasingly used for the description of complex systems. Here we summarize key aspects of the evolvability and robustness of the hierarchical network-set of macromolecules, cells, organisms, and ecosystems. Listing…

分子网络 · 定量生物学 2010-10-05 Huba J. M. Kiss , Agoston Mihalik , Tibor Nanasi , Balint Ory , Zoltan Spiro , Csaba Soti , Peter Csermely

A multiphasic constitutive model of the skin that implicitly accounts for the process of intrinsic (i.e.\ chronological) ageing via variation of the constitutive parameters is proposed. The structurally-motivated constitutive formulation…

生物物理 · 物理学 2018-01-18 D Pond , A McBride , L Davids , B D Reddy , G Limbert

Complex spatiotemporal structures develop during the process of aging glasses after cooling and of rejuvenating glasses upon heating. The key to understanding these structures is the interplay between the activated reconfiguration events…

软凝聚态物质 · 物理学 2008-12-17 Peter G. Wolynes

Biological systems are majorly dependent on their property of bistability in order to exhibit nongenetic heterogeneity in terms of cellular morphology and physiology. Spatial patterns of phenotypically heterogeneous cells, arising due to…

定量方法 · 定量生物学 2023-01-25 Priya Chakraborty , Ushasi Roy , Mohit K. Jolly , Sayantari Ghosh

We are interested in the out of equilibrium phenomena observed in the electrical conductance of disordered insulators at low temperature, which may be signatures of the electron coulomb glass state. The present work is devoted to the…

无序系统与神经网络 · 物理学 2010-08-09 Thierry Grenet , Julien Delahaye

In this doctoral thesis, we investigate the complex interplay between temporal dynamics associated with aging and memory and their effects on social and economic systems. To do so, we combine theoretical modeling, to explore the aging…

物理与社会 · 物理学 2024-10-25 David Abella

In this paper, we review several important features of the out-of-equilibrium dynamics of spin glasses. Starting with the simplest experiments, we discuss the scaling laws used to describe the isothermal aging observed in spin glasses after…

无序系统与神经网络 · 物理学 2009-11-10 V. Dupuis , F. Bert , J. -P. Bouchaud , J. Hammann , F. Ladieu , D. Parker , E. Vincent

Nonequilibrium dynamics of biomembranes with active inclusions is considered. The inclusions represent protein molecules which perform cyclic internal conformational motions driven by the energy brought with ATP ligands. As protein…

软凝聚态物质 · 物理学 2015-05-13 Hsuan-Yi Chen , Alexander S. Mikhailov

Motivated by recent research of aging in E. coli, we explore the effects of aging on bacterial fitness. The disposable soma theory of aging was developed to explain how differences in lifespans and aging rates could be linked to life…

种群与进化 · 定量生物学 2007-05-23 Leah R. Johnson , Marc Mangel

Oscillators are often employed as a model of radiation fields, which may couple to an atom and play an important role for creating and manipulating nonclassical states in quantum metrology, quantum simulation, and quantum information. Aging…

量子物理 · 物理学 2026-02-25 Huining Zhang , X. Z. Hao , X. X. Yi

The relaxations of conductivity after a temporary change of carrier density n_s during the waiting time t_w have been studied in a strongly disordered two-dimensional electron system in Si. At low enough n_s < n_g (n_g - the glass…

强关联电子 · 物理学 2015-05-14 J. Jaroszynski , Dragana Popovic

Advances in healthcare and in the quality of life significantly increase human life expectancy. With the ageing of populations, new un-faced challenges are brought to science. The human body is naturally selected to be well-functioning…

My analysis uses methods developed for data mining microarray experiments, adapted for ageing research. Methods bridge knowledge of statistical mechanics with data mining methods developed in statistical mathematics. Analyses can reveal how…

定量方法 · 定量生物学 2012-12-11 Diana David-Rus

We study aging behavior of aqueous suspension of Laponite as a function of concentration of Laponite, concentration of salt, time elapsed since preparation of suspension (idle time) and temperature by carrying extensive rheological and…

软凝聚态物质 · 物理学 2013-06-25 A. Shahin , Yogesh M Joshi

This paper generalizes a previously published differential equation that describes the relation between the age-specific incidence, remission, and mortality of a disease with its prevalence. The underlying model is a simple compartment…

种群与进化 · 定量生物学 2012-09-07 Ralph Brinks

We consider the dynamics of a suspension of hard sphere-like particles in the proximity of its glass transition, the region where the intermediate scattering functions show significant aging. The time correlation function of the…

软凝聚态物质 · 物理学 2018-10-10 William van Megen , Hans-Joachim Schoepe

An interesting concept that has been underexplored in the context of time-dependent simulations is the correlation of total magnetization, $C(t)$%. One of its main advantages over directly studying magnetization is that we do not need to…

统计力学 · 物理学 2023-10-09 Roberto da Silva , Tânia Tomé , Mário José de Oliveira

Biological aging is characterized by an age-dependent increase in the probability of death and by a decrease in the reproductive capacity. Individual age-dependent rates of survival and reproduction have a strong impact on population…

种群与进化 · 定量生物学 2016-02-03 Arian Šajina , Dario Riccardo Valenzano

The incredible thermo-mechanical properties of biological materials arise from the microscopic scale due to a complex hierarchical mechanism, regulated by microinstabilities at the molecular level. The description of such complex structures…

生物物理 · 物理学 2022-10-26 Luca Bellino