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It is possible to find the optimized radiation dose per session for a radiotherapy (RT) treatment, using a population dynamics model. This has already been done in a previous work for a protocol with 30 sessions and a fixed dose per…

Radiation therapy is an effective and widely accepted form of treatment for many types of cancer that requires extensive computerized planning. Unfortunately, current treatment planning systems have limited or no visual aid that combines…

图形学 · 计算机科学 2018-11-30 Felix G. Hamza-Lup , Ivan Sopin , Omar Zeidan

Radiotherapy treatment planning is a challenging large-scale optimization problem plagued by uncertainty. Following the robust optimization methodology, we propose a novel, spatially based uncertainty set for robust modeling of radiotherapy…

最优化与控制 · 数学 2024-05-28 Noam Goldberg , Mark P. Langer , Shimrit Shtern

The authors propose robust adaptive strategies based on stochastic minimax optimization for a series of simulated treatments on a one-dimensional patient phantom. The plan applied during the first fractions should be able to handle…

最优化与控制 · 数学 2018-10-01 Michelle Böck , Anders Forsgren , Kjell Eriksson , Björn Hårdemark

Rotational setup errors are usually neglected in most clinical centers. An analytical formula is developed to determine the extra margin between clinical target volume (CTV) and planning target volume (PTV) to account for setup errors. The…

医学物理 · 物理学 2014-11-18 Qinghui Zhang , Weijun Xiong , M. Chan , Y. Song , C. Burman

Radiotherapy planning is a highly complex process that often varies significantly across institutions and individual planners. Most existing deep learning approaches for 3D dose prediction rely on reference plans as ground truth during…

计算机视觉与模式识别 · 计算机科学 2025-12-11 Riqiang Gao , Simon Arberet , Martin Kraus , Han Liu , Wilko FAR Verbakel , Dorin Comaniciu , Florin-Cristian Ghesu , Ali Kamen

In robotic radiation therapy, high-energy photon beams from different directions are directed at a target within the patient. Target motion can be tracked by robotic ultrasound and then compensated by synchronous beam motion. However,…

计算工程、金融与科学 · 计算机科学 2024-03-29 Lars Beckers , Stefan Gerlach , Ole Lübke , Alexander Schlaefer , Sibylle Schupp

A central problem in the field of radiation therapy (RT) is how to optimally deliver dose to a patient in a way that fully accounts for anatomical position changes over time. As current RT is a static process, where beam intensities are…

医学物理 · 物理学 2019-09-04 Rodney D. Wiersma , Xinmin Liu

Radiotherapy represents an important phase of treatment for a large number of cancer patients. It is essential that resources used to deliver this treatment are employed effectively. This paper presents a new integer linear programming…

计算工程、金融与科学 · 计算机科学 2011-03-18 Edmund K. Burke , Pedro Leite-Rocha , Sanja Petrovic

Precision medicine incorporates patient-level covariates to tailor treatment decisions, seeking to improve outcomes. In longitudinal studies with time-varying covariates and sequential treatment decisions, precision medicine can be…

统计方法学 · 统计学 2020-08-05 Dylan Spicker , Michael Wallace

This paper deals with the classic radiotherapy dose fractionation problem for cancer tumors concerning the following goals: a) To maximize the effect of radiation on the tumor, restricting the effect produced to the organs at risk (healing…

最优化与控制 · 数学 2021-02-17 Luis Alberto Fernández , Lucía Fernández

Sector duration optimization (SDO) is a problem arising in treatment planning for stereotactic radiosurgery on Gamma Knife. Given a set of isocenter locations, SDO aims to select collimator size configurations and irradiation times thereof…

最优化与控制 · 数学 2022-05-24 Oylum Şeker , Mucahit Cevik , Merve Bodur , Young Lee-Bartlett , Mark Ruschin

Pose estimation is a widely explored problem, enabling many robotic tasks such as grasping and manipulation. In this paper, we tackle the problem of pose estimation for objects that exhibit rotational symmetry, which are common in man-made…

计算机视觉与模式识别 · 计算机科学 2018-10-16 Enric Corona , Kaustav Kundu , Sanja Fidler

Tomography can be used to reveal internal properties of a 3D object using any penetrating wave. Advanced tomographic imaging techniques, however, are vulnerable to both systematic and random errors associated with the experimental…

数值分析 · 数学 2019-02-08 Anthony P. Austin , Zichao Wendy Di , Sven Leyffer , Stefan M. Wild

Stereotactic body radiation therapy (SBRT) refers to focusing high-energy rays in three-dimensional space on the tumor lesion area, reducing the dose received by surrounding normal tissues, which can effectively improve the local control…

医学物理 · 物理学 2024-02-27 Yanqi Zong , Zhengrong Cui , Luqi Lin , Sihao Wang , Yizhi Chen

The Radiotherapy treatment planning optimization process based on a quasi-Newton algorithm with an object function containing dose-volume constraints is not guaranteed to converge when the dose value in the dose-volume constraint is a…

经典分析与常微分方程 · 数学 2008-12-02 I. Hoveijn

We present for the first time a general 6DoF trajectory planning method that can be used in real-time image guided radiation therapy procedures for robotic stabilization of dynamically moving tumor targets. As the radiation beam is always…

医学物理 · 物理学 2018-08-14 Rodney D. Wiersma , Xinmin Liu

Interfractional geometric uncertainties can lead to deviations of the actual delivered dose from the prescribed dose distribution. To better handle these uncertainties during treatment, the authors propose a dynamic framework for robust…

医学物理 · 物理学 2019-05-16 Michelle Böck , Kjell Eriksson , Anders Forsgren

Radiotherapy is one of the primary treatment methods for tumors, but the organ movement caused by respiration limits its accuracy. Recently, 3D imaging from a single X-ray projection has received extensive attention as a promising approach…

图像与视频处理 · 电气工程与系统科学 2024-04-01 Miao Zhu , Qiming Fu , Bo Liu , Mengxi Zhang , Bojian Li , Xiaoyan Luo , Fugen Zhou

The challenge of removing cancerous cells lies in the limitation of organ at risk, which restricts the ability to increase the radiation dose adequately for enhancing treatment effectiveness. This survey provides a comprehensive overview of…

医学物理 · 物理学 2023-07-27 Amir Moslemi , Navid Khaledi
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