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Accurate pressure measurements in micrometric channels are essential for a wide range of microfluidic applications. Existing approaches rely on a variety of sensing mechanisms, but generally require the integration of additional probes or…

光学 · 物理学 2026-05-25 Kiran Acharya , Serge Monneret , Martin Brandenbourger , Thomas Chaigne

In fully-developed pressure-driven flow, the spreading of a dissolved solute is enhanced in the flow direction due to transverse velocity variations in a phenomenon now commonly referred to as Taylor-Aris dispersion. It is well understood…

流体动力学 · 物理学 2022-10-04 Garam Lee , Alan Luner , Jeremy Marzuola , Daniel M. Harris

In microfluidic systems, droplets undergo intricate deformations as they traverse flow-focusing junctions, posing a challenging task for accurate measurement, especially during short transit times. This study investigates the physical…

Deformable microchannels emulate a key characteristic of soft biological systems and flexible engineering devices: the flow-induced deformation of the conduit due to slow viscous flow within. Elucidating the two-way coupling between…

流体动力学 · 物理学 2026-01-14 Anxu Huang , Shrihari D. Pande , Jie Feng , Ivan C. Christov

Long, shallow microchannels embedded in thick soft materials are widely used in microfluidic devices for lab-on-a-chip applications. However, the bulging effect caused by fluid--structure interactions between the internal viscous flow and…

流体动力学 · 物理学 2019-12-03 Xiaojia Wang , Ivan C. Christov

We report on experiments that consist in deforming a collection of monodisperse droplets produced by a microfluidic chip through a flow-focusing device. We show that a proper numerical modelling of the flow is necessary to access the stress…

软凝聚态物质 · 物理学 2018-05-23 Corentin Trégouët , Thomas Salez , Cécile Monteux , Mathilde Reyssat

The emerging field of deformable microfluidics widely employed in the Lab-on-a-Chip and MEMS communities offers an opportunity to study a relatively under-examined physics. The main objective of this work is to provide a deeper insight into…

流体动力学 · 物理学 2018-09-14 Aryan Mehboudi , Junghoon Yeom

Characterizing the elastic properties of soft materials through bulge testing relies on accurate measurement of deformation, which is experimentally challenging. To avoid measuring deformation, we propose a hydrodynamic bulge test for…

软凝聚态物质 · 物理学 2020-03-17 Vishal Anand , Sanjan C. Muchandimath , Ivan C. Christov

A microfluidic device is constructed from PDMS with a single channel having a short section that is a thin flexible membrane, in order to investigate the complex fluid-structure interaction that arises between a flowing fluid and a…

软凝聚态物质 · 物理学 2020-07-03 Debadi Chakraborty , J. Ravi Prakash , Leslie Yeo , James Friend

Microfluidic channels are integral to biomedical technology and process engineering, offering versatility in handling fluids with complex properties, often a combination of viscous and elastic attributes. Despite significant advancements in…

软凝聚态物质 · 物理学 2025-09-29 Sampad Laha , Siddhartha Mukherjee , Suman Chakraborty

This paper presents a new method to obtain the deformation distribution on the main reflector of an antenna only by measuring the electric intensity on a spherical surface with the focal point as the center of the sphere, regardless of…

天体物理仪器与方法 · 物理学 2021-12-08 Qian Ye , Boyang Wang , Qiang Yao , Jinqing Wang , Qinghui Liu , Zhiqiang Shen

The ability of detecting and separating CTCs can play a key role in early cancer detection and treatment. In recent years, there has been growing interest in using deformability-based CTC separation microfilters due to their simplicity and…

细胞行为 · 定量生物学 2016-01-11 Mohammad Aghaamoo , Zhifeng Zhang , Xiaolin Chen , Jie Xu

We present a comparative modelling study of fluid-structure interactions in microchannels. Through a mathematical analysis based on plate theory and the lubrication approximation for low-Reynolds-number flow, we derive models for the flow…

流体动力学 · 物理学 2020-07-10 Tanmay C. Shidhore , Ivan C. Christov

Laminar flow in devices fabricated from soft materials causes deformation of the passage geometry, which affects the flow rate--pressure drop relation. For a given pressure drop, in channels with narrow rectangular cross-section, the flow…

流体动力学 · 物理学 2018-02-23 Ivan C. Christov , Vincent Cognet , Tanmay C. Shidhore , Howard A. Stone

Deformation based circulating tumor cell (CTC) microchips are a representative diagnostic device for early cancer detection. This type of device usually involves a process of CTC trapping in a confined microgeometry. Further understanding…

软凝聚态物质 · 物理学 2016-01-11 Zhifeng Zhang , Xiaolin Chen , Jie Xu

The manipulation and control of microparticles through non-intrusive methods is pivotal in biomedical applications such as cell sorting and cell focusing. Although several experimental and numerical studies have been dedicated to single…

流体动力学 · 物理学 2023-12-20 Giancarlo Esposito , Gaetano D'Avino , Massimiliano Maria Villone

We present a simple but effective method to measure the pressure inside a deformable micro-channel using laser scattering in a translucent Scotch tape. Our idea exploits the fact that the speckle pattern generated by a turbid layer is…

Flow through porous, elastically deforming media is present in a variety of natural contexts ranging from large-scale geophysics to cellular biology. In the case of incompressible constituents, the porefluid pressure acts as a Lagrange…

流体动力学 · 物理学 2022-06-30 Nicholas J. Derr , Chris H. Rycroft

The migration characteristics of a suspended deformable droplet in a parallel plate microchannel is studied, both analytically and numerically, under the combined influence of a constant temperature gradient in the transverse direction and…

流体动力学 · 物理学 2017-05-05 Sayan Das , Shubhadeep Mandal , Suman Chakraborty

The shape of a microchannel during flow through it is instrumental to understanding the physics that govern various phenomena ranging from rheological measurements of fluids to separation of particles and cells. Two commonly used approaches…

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