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When inhibitory neurons constitute about 40% of neurons they could have an important antinociceptive role, as they would easily regulate the level of activity of other neurons. We consider a simple network of cortical spiking neurons with…

神经元与认知 · 定量生物学 2014-01-28 Fernando Montani , Emilia B. Deleglise , Osvaldo A. Rosso

Based on numerical simulation of Hodgkin and Huxley type neuron stimulated from many synaptic inputs, an abstract concept of signal processing in individual neuron is proposed. In the concept proposed, neuron performs binding of synaptic…

神经元与认知 · 定量生物学 2008-01-03 A. K. Vidybida

Multivariate Hawkes processes are past-dependant point processes originally introduced to model excitation effects, later extended to a nonlinear framework to account for the opposite effect, known as inhibition. Motivated by applications…

统计方法学 · 统计学 2026-05-12 Sacha Quayle , Anna Bonnet , Maxime Sangnier

The principle of stationary action is a cornerstone of modern physics, providing a powerful framework for investigating dynamical systems found in classical mechanics through to quantum field theory. However, computational neuroscience,…

神经元与认知 · 定量生物学 2020-10-08 Erik D. Fagerholm , Karl J. Friston , Rosalyn J. Moran , Robert Leech

Hopfield models, originally developed to study memory retrieval in neural networks, have become versatile tools for modeling diverse biological systems in which function emerges from collective dynamics. In this review, we provide a…

生物物理 · 物理学 2025-06-17 Maria Yampolskaya , Pankaj Mehta

Network control theory has recently emerged as a promising approach for understanding brain function and dynamics. By operationalizing notions of control theory for brain networks, it offers a fundamental explanation for how brain dynamics…

定量方法 · 定量生物学 2020-03-20 Shikuang Deng , Shi Gu

We give an introductory account of the recent hyperdensity functional theory for the equilibrium statistical mechanics of soft matter systems [F. Samm\"uller et al., Phys. Rev. Lett. 133, 098201 (2024); 10.1103/PhysRevLett.133.098201].…

软凝聚态物质 · 物理学 2025-02-27 Florian Sammüller , Matthias Schmidt

Mathematical modelling of the macroscopic electrical activity of the brain is highly non-trivial and requires a detailed understanding of not only the associated mathematical techniques, but also the underlying physiology and anatomy.…

神经元与认知 · 定量生物学 2023-06-22 Blake J. Cook , Andre D. H. Peterson , Wessel Woldman , John R. Terry

Recent studies have revealed the complex structure of nerve signals in axons. There is experimental evidence that the propagation of an electrical signal (action potential) is accompanied by mechanical and thermal effects. In this paper,…

生物物理 · 物理学 2020-09-21 Jüri Engelbrecht , Kert Tamm , Tanel Peets

Neural activity fluctuates over a wide range of timescales within and across brain areas. Experimental observations suggest that diverse neural timescales reflect information in dynamic environments. However, how timescales are defined and…

神经元与认知 · 定量生物学 2026-01-21 Roxana Zeraati , Anna Levina , Jakob H. Macke , Richard Gao

The dynamics of neural networks is often characterized by collective behavior and quasi-synchronous events, where a large fraction of neurons fire in short time intervals, separated by uncorrelated firing activity. These global temporal…

无序系统与神经网络 · 物理学 2014-10-03 Raffaella Burioni , Mario Casartelli , Matteo di Volo , Roberto Livi , Alessandro Vezzani

We report the phenomenon of frequency clustering in a network of Hodgkin-Huxley neurons with spike timing-dependent plasticity. The clustering leads to a splitting of a neural population into a few groups synchronized at different…

适应与自组织系统 · 物理学 2019-12-20 Vera Röhr , Rico Berner , Ewandson L. Lameu , Oleksandr V. Popovych , Serhiy Yanchuk

Cellular behavior is governed by gene regulatory processes that are intrinsically dynamic and nonlinear, and are subject to non-negligible amounts of random fluctuations. Such conditions are ubiquitous in physical systems, where they have…

分子网络 · 定量生物学 2011-09-21 Jordi Garcia-Ojalvo

Among the versatile forms of dynamical patterns of activity exhibited by the brain, oscillations are one of the most salient and extensively studied, yet are still far from being well understood. In this paper, we provide various structural…

系统与控制 · 电气工程与系统科学 2021-08-12 Erfan Nozari , Robert Planas , Jorge Cortes

We demonstrate that two key theoretical objects used widely in Computational Neuroscience, the phase-resetting curve (PRC) from dynamics and the spike triggered average (STA) from statistical analysis, are closely related under a wide range…

神经元与认知 · 定量生物学 2007-09-26 G. Bard Ermentrout , Roberto F. Galán Nathaniel N. Urban

Neurofeedback is a form of brain training in which subjects are fed back information about some measure of their brain activity which they are instructed to modify in a way thought to be functionally advantageous. Over the last twenty…

神经元与认知 · 定量生物学 2018-05-15 David Papo

Bursting neurons are considered to be a potential cause of over-excitability and seizure susceptibility. The functional influence of these neurons in extended epileptic networks is still poorly understood. There is mounting evidence that…

神经元与认知 · 定量生物学 2016-10-07 Christian Geier , Alexander Rothkegel , Christian E. Elger , Klaus Lehnertz

The initial version of the planned paper has gone through a major revision in 2025. First, the paper ended up growing a bit too long, and as a result of that, we decided to split it into two parts. The first part focuses on the model for…

生物物理 · 物理学 2025-07-02 Kert Tamm , Tanel Peets , Jüri Engelbrecht

The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

神经元与认知 · 定量生物学 2020-12-02 Hui Wei

We provide a prototypical description of mechanically-induced collective conformational change (folding), relevant in a variety of biological contexts from muscle contraction to hair cell gating and integrin binding. Our study is inspired…

生物物理 · 物理学 2017-09-14 Matthieu Caruel , Lev Truskinovsky