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Synthetic generation of three-dimensional cell models from histopathological images aims to enhance understanding of cell mutation, and progression of cancer, necessary for clinical assessment and optimal treatment. Classical reconstruction…

图像与视频处理 · 电气工程与系统科学 2021-02-09 Yoav Alon , Xiang Yu , Huiyu Zhou

The 3-dimensional (3D) structure of the genome is of significant importance for many cellular processes. In this paper, we study the problem of reconstructing the 3D structure of chromosomes from Hi-C data of diploid organisms, which poses…

基因组学 · 定量生物学 2024-05-30 Diego Cifuentes , Jan Draisma , Oskar Henriksson , Annachiara Korchmaros , Kaie Kubjas

Cellular processes are governed by macromolecular complexes inside the cell. Study of the native structures of macromolecular complexes has been extremely difficult due to lack of data. With recent breakthroughs in Cellular electron cryo…

定量方法 · 定量生物学 2018-06-12 Chengqian Che , Ruogu Lin , Xiangrui Zeng , Karim Elmaaroufi , John Galeotti , Min Xu

Current in vivo microscopy allows us detailed spatiotemporal imaging (3D+t) of complete organisms and offers insights into their development on the cellular level. Even though the imaging speed and quality is steadily improving,…

图像与视频处理 · 电气工程与系统科学 2020-01-31 Sourabh Bhide , Ralf Mikut , Maria Leptin , Johannes Stegmaier

Robots operating in unstructured environments often require accurate and consistent object-level representations. This typically requires segmenting individual objects from the robot's surroundings. While recent large models such as Segment…

机器人学 · 计算机科学 2025-04-07 Haozhan Tang , Tianyi Zhang , Oliver Kroemer , Matthew Johnson-Roberson , Weiming Zhi

Cryogenic electron microscopy (cryo-EM) has become an enabling technology in drug discovery and in understanding molecular bases of disease by producing near-atomic resolution (less than 0.4 nm) 3D reconstructions of biological…

计算机视觉与模式识别 · 计算机科学 2020-07-23 Hong Xu , David E. Timm , Shireen Y. Elhabian

Robust and accurate nuclei centroid detection is important for the understanding of biological structures in fluorescence microscopy images. Existing automated nuclei localization methods face three main challenges: (1) Most of object…

图像与视频处理 · 电气工程与系统科学 2021-11-05 Liming Wu , Shuo Han , Alain Chen , Paul Salama , Kenneth W. Dunn , Edward J. Delp

A wide range of techniques can be considered for segmentation of images of nanostructured surfaces. Manually segmenting these images is time-consuming and results in a user-dependent segmentation bias, while there is currently no consensus…

图像与视频处理 · 电气工程与系统科学 2020-08-31 Steff Farley , Jo E. A. Hodgkinson , Oliver M. Gordon , Joanna Turner , Andrea Soltoggio , Philip J. Moriarty , Eugenie Hunsicker

Accurate 3D microscopy image segmentation is critical for quantitative bioimage analysis but even state-of-the-art foundation models yield error-prone results. Therefore, manual curation is still widely used for either preparing…

The prospect of neural reconstruction from Electron Microscopy (EM) images has been elucidated by the automatic segmentation algorithms. Although segmentation algorithms eliminate the necessity of tracing the neurons by hand, significant…

计算机视觉与模式识别 · 计算机科学 2015-09-29 Toufiq Parag

The optimal treatment strategy of newly diagnosed glioma is strongly influenced by tumour malignancy. Manual non-invasive grading based on MRI is not always accurate and biopsies to verify diagnosis negatively impact overall survival. In…

图像与视频处理 · 电气工程与系统科学 2019-08-08 Milan Decuyper , Roel Van Holen

Shape-based regularization has proven to be a useful method for delineating objects within noisy images where one has prior knowledge of the shape of the targeted object. When a collection of possible shapes is available, the specification…

计算机视觉与模式识别 · 计算机科学 2014-05-05 Joshua C. Chang , Tom Chou

We have developed an automatic method for segmenting fluorescence lifetime (FLT) imaging microscopy (FLIM) images of cells inspired by a multi-resolution community detection (MCD) based network segmentation method. The image processing…

医学物理 · 物理学 2014-01-06 Dandan Hu , Pinaki Sarder , Peter Ronhovde , Sandra Orthaus , Samuel Achilefu , Zohar Nussinov

Microscopy image analysis often requires the segmentation of objects, but training data for this task is typically scarce and hard to obtain. Here we propose DenoiSeg, a new method that can be trained end-to-end on only a few annotated…

计算机视觉与模式识别 · 计算机科学 2020-06-12 Tim-Oliver Buchholz , Mangal Prakash , Alexander Krull , Florian Jug

Recent studies suggest a potential link between the physical structure of mitochondria and neurodegenerative diseases. With advances in Electron Microscopy techniques, it has become possible to visualize the boundary and internal membrane…

计算机视觉与模式识别 · 计算机科学 2025-02-11 Faris Serdar Taşel , Efe Çiftci

Image segmentation is a fundamental step for the interpretation of Remote Sensing Images. Clustering or segmentation methods usually precede the classification task and are used as support tools for manual labeling. The most common…

计算机视觉与模式识别 · 计算机科学 2022-03-08 Kiran Mantripragada , Faisal Z. Qureshi

Magnetic Resonance Imaging (MRI) is essential for noninvasive generation of high-quality images of human tissues. Accurate segmentation of MRI data is critical for medical applications like brain anatomy analysis and disease detection.…

最优化与控制 · 数学 2025-10-17 Laura Antonelli , Valentina De Simone , Marco Viola

Automatic cell segmentation in microscopy images works well with the support of deep neural networks trained with full supervision. Collecting and annotating images, though, is not a sustainable solution for every new microscopy database…

计算机视觉与模式识别 · 计算机科学 2020-07-06 Youssef Dawoud , Julia Hornauer , Gustavo Carneiro , Vasileios Belagiannis

Generally, microscopy image analysis in biology relies on the segmentation of individual nuclei, using a dedicated stained image, to identify individual cells. However stained nuclei have drawbacks like the need for sample preparation, and…

图像与视频处理 · 电气工程与系统科学 2022-11-08 Gendarme Mathieu , Lambert Annika M. , El Debs Bachir

Current biological and medical research is aimed at obtaining a detailed spatiotemporal map of a live cell's interior to describe and predict cell's physiological state. We present here an algorithm for complete 3-D modelling of cellular…