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In a generic neuron model, we present the linear response theory for the firing rate in response to both time dependent input currents and noise amplitudes. In both cases the signal transmission is strongly attenuated for frequencies above…

生物物理 · 物理学 2007-05-23 Bjoern Naundorf , Theo Geisel , Fred Wolf

Variability in neural responses is an ubiquitous phenomenon in neurons, usually modeled with stochastic differential equations. In particular, stochastic integrate-and-fire models are widely used to simplify theoretical studies. The…

神经元与认知 · 定量生物学 2009-06-12 Eugenio Urdapilleta , Ines Samengo

The macroscopic dynamics of large populations of neurons can be mathematically analyzed using low-dimensional firing-rate or neural-mass models. However, these models fail to capture spike synchronization effects of stochastic spiking…

神经元与认知 · 定量生物学 2023-04-20 Bastian Pietras , Noé Gallice , Tilo Schwalger

The dominant modeling framework for understanding cortical computations are heuristic firing rate models. Despite their success, these models fall short to capture spike synchronization effects, to link to biophysical parameters and to…

神经元与认知 · 定量生物学 2019-09-24 Tilo Schwalger , Anton V. Chizhov

The activity of neurons within brain circuits has been ubiquitously reported to be correlated. The impact of these correlations on brain function has been extensively investigated. Correlations can in principle increase or decrease the…

神经元与认知 · 定量生物学 2025-07-24 Miguel Ibáñez-Berganza , Giulio Bondanelli , Stefano Panzeri

Sequences of events in noise-driven excitable systems with slow variables often show serial correlations among their intervals of events. Here, we employ a master equation for general non-renewal processes to calculate the interval and…

生物物理 · 物理学 2011-05-23 Farzad Farkhooi , Eilif Muller , Martin P. Nawrot

Cortical neurons include many sub-cellular processes, operating at multiple timescales, which may affect their response to stimulation through non-linear and stochastic interaction with ion channels and ionic concentrations. Since new…

神经元与认知 · 定量生物学 2014-05-01 Daniel Soudry , Ron Meir

Recurrently connected neuron populations play key roles in sensory perception and memory storage across various brain regions. While these populations are often assumed to encode information through firing rates, this method becomes…

神经元与认知 · 定量生物学 2025-09-05 Mauricio Girardi-Schappo , Leonard Maler , André Longtin

Neurons in the intact brain receive a continuous and irregular synaptic bombardment from excitatory and inhibitory pre-synaptic neurons, which determines the firing activity of the stimulated neuron. In order to investigate the influence of…

神经元与认知 · 定量生物学 2017-05-23 Simona Olmi , David Angulo-Garcia , Alberto Imparato , Alessandro Torcini

The mutual information between stimulus and spike-train response is commonly used to monitor neural coding efficiency, but neuronal computation broadly conceived requires more refined and targeted information measures of input-output joint…

神经元与认知 · 定量生物学 2015-04-21 Sarah E. Marzen , Michael R. DeWeese , James P. Crutchfield

Recurrent neural networks are powerful tools for understanding and modeling computation and representation by populations of neurons. Continuous-variable or "rate" model networks have been analyzed and applied extensively for these…

神经元与认知 · 定量生物学 2016-01-29 Brian DePasquale , Mark M. Churchland , L. F. Abbott

The rate coding response of a single peripheral sensory neuron in the asymptotic, near-equilibrium limit can be derived using information theory, asymptotic Bayesian statistics and a theory of complex systems. Almost no biological knowledge…

神经元与认知 · 定量生物学 2020-12-14 Willy Wong

We present a theoretical study aiming at model fitting for sensory neurons. Conventional neural network training approaches are not applicable to this problem due to lack of continuous data. Although the stimulus can be considered as a…

神经元与认知 · 定量生物学 2017-09-28 R. Ozgur Doruk , Kechen Zhang

In this correspondence information theoretical tools are used to investigate the statistical properties of modeled cochlear nucleus globular bushy cell spike trains. The firing patterns are obtained from a simulation software that generates…

神经元与认知 · 定量生物学 2012-04-25 Andrea Grigorescu , Marek Rudnicki , Michael Isik , Werner Hemmert , Stefano Rini

Understanding how stimuli and synaptic connectivity in uence the statistics of spike patterns in neural networks is a central question in computational neuroscience. Maximum Entropy approach has been successfully used to characterize the…

生物物理 · 物理学 2016-11-26 Rodrigo Cofre , Bruno Cessac

We examine the stability and qualitative dynamics of stochastic neuronal networks specified as multivariate nonlinear Hawkes processes and related point-process generalized linear models that incorporate both auto- and cross-history…

无序系统与神经网络 · 物理学 2019-12-13 Dmitrii Todorov , Wilson Truccolo

This paper introduces a class of stochastic models of interacting neurons with emergent dynamics similar to those seen in local cortical populations, and compares them to very simple reduced models driven by the same mean excitatory and…

神经元与认知 · 定量生物学 2017-11-07 Yao Li , Logan Chariker , Lai-Sang Young

We describe a new, computationally simple method for analyzing the dynamics of neuronal spike trains driven by external stimuli. The goal of our method is to test the predictions of simple spike-generating models against extracellularly…

神经元与认知 · 定量生物学 2007-05-23 Daniel S. Reich , Jonathan D. Victor , Bruce W. Knight

Collective dynamics of spiking networks of neurons has been of central interest to both computation neuroscience and network science. Over the past years a new generation of neural population models based on exact reductions (ER) of spiking…

神经元与认知 · 定量生物学 2023-10-24 Inês C. Guerreiro , Matteo di Volo , Boris Gutkin

Recent studies of cortical neurons driven by fluctuating currents revealed cutoff frequencies for action potential encoding of several hundred Hz. Theoretical studies of biophysical neuron models have predicted a much lower cutoff frequency…

神经元与认知 · 定量生物学 2015-05-27 Wei Wei , Fred Wolf
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