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High-throughput screening techniques, such as microscopy imaging of cellular responses to genetic and chemical perturbations, play a crucial role in drug discovery and biomedical research. However, robust perturbation screening for…

计算机视觉与模式识别 · 计算机科学 2025-07-16 Jiayuan Chen , Thai-Hoang Pham , Yuanlong Wang , Ping Zhang

In automated planning, recognising the goal of an agent from a trace of observations is an important task with many applications. The state-of-the-art approaches to goal recognition rely on the application of planning techniques, which…

人工智能 · 计算机科学 2022-10-26 Mattia Chiari , Alfonso E. Gerevini , Luca Putelli , Francesco Percassi , Ivan Serina

The configuration database is one of the vital systems in the BaBar on-line system. It provides services for the different parts of the data acquisition system and control system, which require run-time parameters. The original design and…

数据库 · 计算机科学 2007-05-23 R. Bartoldus , G. Dubois-Felsmann , Y. Kolomensky , A. Salnikov

The advent of large scale, high-throughput genomic screening has introduced a wide range of tests for diagnostic purposes. Prominent among them are tests using miRNA expression levels. Genomics and proteomics now provide expression levels…

基因组学 · 定量生物学 2016-11-08 Neerja Garikipati

Genetic interactions and protein co-dependencies shape cellular fitness, buffering capacity, and disease vulnerability. However, systematic integration of co-dependency relationships across heterogeneous datasets remains limited. Here, we…

The rapid growth of Electronic Health Records (EHRs), as well as the accompanied opportunities in Data-Driven Healthcare (DDH), has been attracting widespread interests and attentions. Recent progress in the design and applications of deep…

机器学习 · 计算机科学 2017-09-07 Zhengping Che , Yu Cheng , Shuangfei Zhai , Zhaonan Sun , Yan Liu

In the realm of big data and digital healthcare, Electronic Health Records (EHR) have become a rich source of information with the potential to improve patient care and medical research. In recent years, machine learning models have…

机器学习 · 计算机科学 2024-10-10 Suhan Cui , Prasenjit Mitra

We present a novel approach to online multi-target tracking based on recurrent neural networks (RNNs). Tracking multiple objects in real-world scenes involves many challenges, including a) an a-priori unknown and time-varying number of…

计算机视觉与模式识别 · 计算机科学 2016-12-08 Anton Milan , Seyed Hamid Rezatofighi , Anthony Dick , Ian Reid , Konrad Schindler

Since microRNAs (miRNAs) play a crucial role in post-transcriptional gene regulation, miRNA identification is one of the most essential problems in computational biology. miRNAs are usually short in length ranging between 20 and 23 base…

机器学习 · 计算机科学 2016-05-04 Seunghyun Park , Seonwoo Min , Hyunsoo Choi , Sungroh Yoon

The data landscape is rich with structured data, often of high value to organizations, driving important applications in data analysis and machine learning. Recent progress in representation learning and generative models for such data has…

信息检索 · 计算机科学 2025-05-20 Xingyu Ji , Parker Glenn , Aditya G. Parameswaran , Madelon Hulsebos

High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…

The emergence of the Next Generation Sequencing increases drastically the volume of transcriptomic data. Although many standalone algorithms and workflows for novel microRNA (miRNA) prediction have been proposed, few are designed for…

分布式、并行与集群计算 · 计算机科学 2025-01-31 Chao-Jung Wu , Amine M. Remita , Abdoulaye Baniré Diallo

This paper presents a Poisson multi-Bernoulli mixture (PMBM) conjugate prior for multiple extended object filtering. A Poisson point process is used to describe the existence of yet undetected targets, while a multi-Bernoulli mixture…

统计计算 · 统计学 2019-12-09 Karl Granstrom , Maryam Fatemi , Lennart Svensson

Goal recognition aims to infer an agent's goal from observations of its behaviour. In realistic settings, recognition can benefit from exploiting hierarchical task structure and reasoning under uncertainty. Planning-based goal recognition…

符号计算 · 计算机科学 2026-04-27 Chenyuan Zhang , Katherine Ip , Hamid Rezatofighi , Buser Say , Mor Vered

Click-through rate (CTR) prediction tasks play a pivotal role in real-world applications, particularly in recommendation systems and online advertising. A significant research branch in this domain focuses on user behavior modeling. Current…

信息检索 · 计算机科学 2024-04-18 Hengyu Zhang , Junwei Pan , Dapeng Liu , Jie Jiang , Xiu Li

A new family of Intensional RDBs (IRDBs), introduced in [1], extends the traditional RDBs with the Big Data and flexible and 'Open schema' features, able to preserve the user-defined relational database schemas and all preexisting user's…

数据库 · 计算机科学 2014-04-11 Zoran Majkic

Growing evidence from recent studies implies that microRNA or miRNA could serve as biomarkers in various complex human diseases. Since wet-lab experiments are expensive and time-consuming, computational techniques for miRNA-disease…

定量方法 · 定量生物学 2021-11-30 Thi Ngan Dong , Megha Khosla

The Big Data landscape poses challenges in managing diverse data formats, requiring efficient storage and processing for high-quality analysis. Effective metadata management is crucial for organizing, accessing, and reusing data within…

数据库 · 计算机科学 2025-03-21 Claudia Diamantini , Alessandro Mele , Domenico Potena , Cristina Rossetti , Emanuele Storti

This paper is about creating digital musical instruments where a predictive neural network model is integrated into the interactive system. Rather than predicting symbolic music (e.g., MIDI notes), we suggest that predicting future control…

声音 · 计算机科学 2019-04-11 Charles P Martin , Jim Torresen

This study introduces database expansion using the Minimum Description Length (MDL) algorithm to expand the database for better relation extraction. Different from other previous relation extraction researches, our method improves system…

信息检索 · 计算机科学 2020-07-31 Diyah Puspitaningrum