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Randomized experiments are widely used to estimate causal effects across a variety of domains. However, classical causal inference approaches rely on critical independence assumptions that are violated by network interference, when the…

统计方法学 · 统计学 2022-10-18 Mayleen Cortez , Matthew Eichhorn , Christina Lee Yu

Multi-model inference covers a wide range of modern statistical applications such as variable selection, model confidence set, model averaging and variable importance. The performance of multi-model inference depends on the availability of…

统计理论 · 数学 2019-06-07 Ching-Wei Cheng , Guang Cheng

The study of cause-and-effect is of the utmost importance in many branches of science, but also for many practical applications of intelligent systems. In particular, identifying causal relationships in situations that include hidden…

机器学习 · 统计学 2024-10-14 Luca Castri , Sariah Mghames , Marc Hanheide , Nicola Bellotto

The inference of networks of dependencies by Gaussian Graphical models on high-throughput data is an open issue in modern molecular biology. In this paper we provide a comparative study of three methods to obtain small sample and high…

分子网络 · 定量生物学 2022-03-02 P. F. Stifanelli , T. M. Creanza , R. Anglani , V. C. Liuzzi , S. Mukherjee , N. Ancona

We conjecture that the worst case number of experiments necessary and sufficient to discover a causal graph uniquely given its observational Markov equivalence class can be specified as a function of the largest clique in the Markov…

人工智能 · 计算机科学 2012-06-18 Frederick Eberhardt

We develop a method for reconstructing regulatory interconnection networks between variables evolving according to a linear dynamical system. The work is motivated by the problem of gene regulatory network inference, that is, finding causal…

统计方法学 · 统计学 2018-02-19 Atte Aalto , Jorge Goncalves

Faced with data-driven policies, individuals will manipulate their features to obtain favorable decisions. While earlier works cast these manipulations as undesirable gaming, recent works have adopted a more nuanced causal framing in which…

机器学习 · 计算机科学 2023-02-22 Tom Yan , Shantanu Gupta , Zachary Lipton

Network interference has attracted significant attention in the field of causal inference, encapsulating various sociological behaviors where the treatment assigned to one individual within a network may affect the outcomes of others, such…

机器学习 · 计算机科学 2025-02-11 Zhiheng Zhang , Zichen Wang

Over the last decades, many prognostic models based on artificial intelligence techniques have been used to provide detailed predictions in healthcare. Unfortunately, the real-world observational data used to train and validate these models…

机器学习 · 计算机科学 2023-11-21 Alice Bernasconi , Alessio Zanga , Peter J. F. Lucas , Marco Scutari , Fabio Stella

Estimating causal effects from observational data informs us about which factors are important in an autonomous system, and enables us to take better decisions. This is important because it has applications in selecting a treatment in…

机器学习 · 计算机科学 2021-10-29 Plabon Shaha , Talha Islam Zadid , Ismat Rahman , Md. Mosaddek Khan

An important task in health research is to characterize time-to-event outcomes such as disease onset or mortality in terms of a potentially high-dimensional set of risk factors. For example, prospective cohort studies of Alzheimer's disease…

统计方法学 · 统计学 2024-01-12 Harrison T. Reeder , Sebastien Haneuse , Kyu Ha Lee

Evaluating the causal effect of an intervention on multivariate outcomes is challenging when the outcomes are interdependent and derived rather than directly observed. Effective connectivity, which summarizes the directional neural…

统计方法学 · 统计学 2026-04-02 Haiyue Song , Ani Eloyan , Youjin Lee

The health effects of environmental exposures have been studied for decades, typically using standard regression models to assess exposure-outcome associations found in observational non-experimental data. We propose and illustrate a…

应用统计 · 统计学 2017-09-20 Marie-Abele C. Bind , Donald B. Rubin

The molecular evolution in a gene regulatory network is classically modeled by Markov jump processes. However, the direct simulation of such models is extremely time consuming. Indeed, even the simplest Markovian model, such as the…

概率论 · 数学 2012-11-30 Aurélie Muller-Gueudin

Inferring a graphical model or network from observational data from a large number of variables is a well studied problem in machine learning and computational statistics. In this paper we consider a version of this problem that is relevant…

统计方法学 · 统计学 2013-12-06 Andy Dahl , Victoria Hore , Valentina Iotchkova , Jonathan Marchini

Convenient access to observational data enables us to learn causal effects without randomized experiments. This research direction draws increasing attention in research areas such as economics, healthcare, and education. For example, we…

社会与信息网络 · 计算机科学 2019-12-03 Ruocheng Guo , Jundong Li , Huan Liu

There is abundant observational data in the software engineering domain, whereas running large-scale controlled experiments is often practically impossible. Thus, most empirical studies can only report statistical correlations -- instead of…

软件工程 · 计算机科学 2024-10-03 Carlo A. Furia , Richard Torkar , Robert Feldt

This paper investigates methods for estimating the optimal stochastic control policy for a Markov Decision Process with unknown transition dynamics and an unknown reward function. This form of model-free reinforcement learning comprises…

机器学习 · 计算机科学 2019-12-06 Brandon Trabucco , Albert Qu , Simon Li , Ganeshkumar Ashokavardhanan

Gaussian graphical models are often used to infer gene networks based on microarray expression data. Many scientists, however, have begun using high-throughput sequencing technologies to measure gene expression. As the resulting…

应用统计 · 统计学 2012-05-30 Genevera I. Allen , Zhandong Liu

In recent years, there has been a growing interest in using machine learning techniques for the estimation of treatment effects. Most of the best-performing methods rely on representation learning strategies that encourage shared behavior…

机器学习 · 计算机科学 2024-04-19 Roger Pros , Jordi Vitrià