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Nutritional assessment is key in order to make decisions about the nature and cause of nutrition related health issues that affect an individual. The systematic process of collecting and interpreting relevant nutrition information, however,…

计算机与社会 · 计算机科学 2019-07-18 Lars Brenna , Håvard D. Johansen , Dag Johansen

This article studies the quasi-stationary behaviour of multidimensional birth and death processes, modeling the interaction between several species, absorbed when one of the coordinates hits 0. We study models where the absorption rate is…

概率论 · 数学 2015-08-14 Nicolas Champagnat , Denis Villemonais

In many statistical and econometric applications, we gather individual samples from various interconnected populations that undeniably exhibit common latent structures. Utilizing a model that incorporates these latent structures for such…

统计方法学 · 统计学 2023-09-19 Archer Gong Zhang , Jiahua Chen

Functional data that are nonnegative and have a constrained integral can be considered as samples of one-dimensional density functions. Such data are ubiquitous. Due to the inherent constraints, densities do not live in a vector space and,…

统计理论 · 数学 2016-01-13 Alexander Petersen , Hans-Georg Müller

From flocking birds to schooling fish, organisms interact to form collective dynamics across the natural world. Self-organization is present at smaller scales as well: cells interact and move during development to produce patterns in fish…

定量方法 · 定量生物学 2024-07-16 Alexandria Volkening

The use of high-dimensional data for targeted therapeutic interventions requires new ways to characterize the heterogeneity observed across subgroups of a specific population. In particular, models for partially exchangeable data are needed…

统计方法学 · 统计学 2020-08-18 Francesco Denti , Federico Camerlenghi , Michele Guindani , Antonietta Mira

We suggest a natural approach that leads to a modification of classical quasispecies models and incorporates the possibility of population extinction in addition to growth. The resulting modified models are called open. Their essential…

种群与进化 · 定量生物学 2019-03-25 Ivan Yegorov , Artem S. Novozhilov , Alexander S. Bratus

Mixture models, such as Gaussian mixture models, are widely used in machine learning to represent complex data distributions. A key challenge, especially in high-dimensional settings, is to determine the mixture order and estimate the…

最优化与控制 · 数学 2025-09-30 Srećko Đurašinović , Jean-Bernard Lasserre , Victor Magron

Intracellular structural alterations are hallmark of several disease conditions and treatment modalities. However, robust methods to quantify these changes are scarce. In view of this, we introduce a new method to quantify structural…

This paper presents a novel framework for the modeling of biological networks. It makes use of recent tools analyzing the robust satisfaction of properties of (hybrid) dynamical systems. The main challenge of this approach as applied to…

计算工程、金融与科学 · 计算机科学 2012-08-22 Nicolas Mobilia , Alexandre Donzé , Jean Marc Moulis , Éric Fanchon

Real food web data available in the literature presents us with the relations between various species, sizes of these species, metabolic types of the species and other useful information, which allows us to define parameters for the…

种群与进化 · 定量生物学 2016-10-25 Alexander Pimenov

This application paper investigates the stability of hydrogen bonds (H-bonds), as characterized by the Quantum Theory of Atoms in Molecules (QTAIM). First, we contribute a database of 4544 electron densities associated to four isomers of…

机器学习 · 计算机科学 2025-07-17 Thomas Daniel , Malgorzata Olejniczak , Julien Tierny

The folding dynamics of small single-domain proteins is a current focus of simulations and experiments. Many of these proteins are 'two-state folders', i.e. proteins that fold rather directly from the denatured state to the native state,…

生物大分子 · 定量生物学 2020-01-08 Thomas R. Weikl

Recent studies of animal social networks have significantly increased our understanding of animal behavior, social interactions, and many important ecological and epidemiological processes. However, most of the studies are at low temporal…

种群与进化 · 定量生物学 2017-02-08 Shi Chen , Amiyaal Ilany , Brad J. White , Michael W. Sanderson , Cristina Lanzas

Biological cells are built up from many different constituents of varying size and stiffness which all contribute to the cell's mechanical properties. Despite this heterogeneity, in the analysis of experimental measurements such as atomic…

生物物理 · 物理学 2023-05-18 Sebastian Wohlrab , Sebastian J. Müller , Stephan Gekle

The bulk properties (lattice constants, bulk moduli, and cohesive energies) of alkali, alkaline-earth, and transition metals are studied within the framework of the recently developed meta-GGA (meta-Generalized Gradient Approximation)…

材料科学 · 物理学 2018-11-14 Subrata Jana , Kedar Sharma , Prasanjit Samal

One of the hallmarks of biological organisms is their ability to integrate disparate information sources to optimize their behavior in complex environments. How this capability can be quantified and related to the functional complexity of…

种群与进化 · 定量生物学 2011-11-08 Jeffrey Edlund , Nicolas Chaumont , Arend Hintze , Christof Koch , Giulio Tononi , Christoph Adami

Water activity and its relationship with interactions stabilising lamellar stacks of mixed lipid bilayers in their fluid state are investigated by means of osmotic pressure measurements coupled with small-angle x-ray scattering. The…

The buckling of a soft elastic sample under growth or swelling has highlighted a new interest in materials science, morphogenesis, and biology or physiology. Indeed, the change of mass or volume is a common fact of any living species, and…

软凝聚态物质 · 物理学 2023-09-21 Martine Ben Amar

The origin and shape of metabolic scaling has been controversial since Kleiber found that basal metabolic rate of animals seemed to vary as a power law of their body mass with exponent 3/4, instead of 2/3, as a surface-to-volume argument…

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