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In the present study, the origin of the anti-quorum sensing (QS) activities of several members of a recently synthesized and in vitro tested class of lactone and thiolactone based inhibitors were computationally investigated. Docking and…

生物大分子 · 定量生物学 2013-05-17 Marawan Ahmed , Stefanie Bird , Feng Wang , Enzo A. Palombo

Microorganisms employ sophisticated mechanisms for intercellular communication and environmental sensing, with quorum sensing serving as a fundamental regulatory process. Dysregulation of quorum sensing has been implicated in various…

新兴技术 · 计算机科学 2025-09-30 O. Tansel Baydas , Efe Yatgin , Ozgur B. Akan

The exchange of small molecular signals within microbial populations is generally referred to as quorum sensing (QS). QS is ubiquitous in nature and enables microorganisms to respond to fluctuations in living environments by working…

细胞行为 · 定量生物学 2019-09-16 Yuting Fang , Adam Noel , Andrew W. Eckford , Nan Yang

Molecular Communication (MC) utilizes chemical molecules to transmit information, introducing innovative strategies for pharmaceutical interventions and enhanced immune system monitoring. This paper explores Molecular communication based…

生物大分子 · 定量生物学 2024-12-31 Shees Zulfiqar , Ozgur B. Akan

Microbial communities frequently communicate via quorum sensing (QS), where cells produce, secrete, and respond to a threshold level of an autoinducer (AI) molecule, thereby modulating gene expression. However, the biology of QS remains…

分子网络 · 定量生物学 2017-08-02 Tahir Yusufaly , James Q. Boedicker

In quorum sensing (QS), bacteria exchange molecular signals to work together. An analytically-tractable model is presented for characterizing QS signal propagation within a population of bacteria and the number of responsive cooperative…

信息论 · 计算机科学 2020-09-03 Yuting Fang , Adam Noel , Andrew W. Eckford , Nan Yang , Jing Guo

A cooperative drug delivery system is proposed, where quorum sensing (QS), a density-dependent bacterial behavior coordination mechanism, is employed by synthetic bacterium-based nanomachines (B-NMs) for controllable drug delivery. In our…

定量方法 · 定量生物学 2023-03-15 Yuting Fang , Stuart T. Johnston , Matt Faria , Xinyu Huang , Andrew W. Eckford , Jamie Evans

Axions, hypothetical particles theorized to solve the strong CP-problem, are presently being considered as strong candidates as cold dark matter constituents. The signal power of resonant-based axion detectors, known as haloscopes, is…

We offer new high-performance label-free electrochemical impedimetric DNA sensors of non-faradaic type. The DNA sensors based on a platform of crystalline carbon nanotube (CNT) arrays are fabricated by the Langmuir--Blodgett (LB) deposition…

Suspensions of superheated superconducting grains are a detecting composite material. Each grain in the supension is a microcalorimeter with an energy threshold defined by its equatorial magnetic field for a given temperature. The higher…

仪器与探测器 · 物理学 2007-05-23 Roger Bruhre-Dawson , Jacques Maillard , Girard Maurel , Jorge Silva , Georges Waysand

This study aims to screen the antibacterial activity of lactic acid bacteria (LAB) isolated from home-made fermented vegetables against common food borne pathogens. The antagonistic properties of these isolates against Escherichia coli,…

细胞行为 · 定量生物学 2012-06-28 Mahnaz Kazemipoor , Che Wan Jasimah Wan Mohamed Radzi , Khyrunnisa Begum , Iman Yaze

We present the spectra of Complex Organic Molecules (COMs) detected in HOPS 373SW with the Atacama Large Millimeter/submillimeter Array (ALMA). HOPS 373SW, which is a component of a protostellar binary with a separation of 1500 au, has been…

太阳与恒星天体物理 · 物理学 2023-06-30 Jeong-Eun Lee , Giseon Baek , Seokho Lee , Jae-Hong Jeong , Chul-Hwan Kim , Yuri Aikawa , Gregory J. Herczeg , Doug Johnstone , John J. Tobin

Carbon quantum dots (CQDs) are known for their antibacterial properties and ability to inhibit bacteria growth. In the current study, we observed a dopant and concentration-dependency on the antibacterial effect of CQDs. High concentrations…

Quorum sensing is the mechanism by which bacteria communicate and synchronize group behaviors. Quantitative information on parameters such as the copy number of particular quorum-sensing proteins should contribute strongly to understanding…

定量方法 · 定量生物学 2015-05-14 Shu-Wen Teng , Yufang Wang , Kimberly C. Tu , Tao Long , Pankaj Mehta , Ned S. Wingreen , Bonnie L. Bassler , N. P. Ong

We have demonstrated atomically thin, quantum capacitance-limited, field-effect transistors (FETs) that enable the detection of pH changes with ~75-fold higher sensitivity (4.4 V/pH) over the Nernst value of 59 mV/pH at room temperature…

Genetic oscillators play important roles in cell life regulation. The regulatory efficiency usually depends strongly on the emergence of stable collective dynamic modes, which requires designing the interactions between genetic networks. We…

生物物理 · 物理学 2017-02-23 Edward H. Hellen , Evgeny Volkov

We extend the survey for organics in the southern hemisphere by observing two cores in the Chamaeleon complex using NASA's Deep Space Network 70-m antenna in Canberra, Australia, over the frequency range of 18 to 25 GHz. We surveyed the…

G31.41+0.31 is a well known chemically rich hot molecular core (HMC). Using Band 3 observations of Atacama Large Millimeter Array (ALMA), we have analyzed the chemical and physical properties of the source. We have identified methyl…

We study the astrochemical diagnostics of the isolated massive protostar G28.20-0.05. We analyze data from ALMA 1.3~mm observations with resolution of 0.2 arcsec ($\sim$1,000 au). We detect emission from a wealth of species, including…

We present continuum observations from the Atacama Large Millimeter/submillimeter Array (ALMA) of 10 high-redshift ($2.2 \le z \le 2.7$) ultraluminous quasars (QSOs) and constrain the presence of hot, ionized, circum-galactic gas in a…

星系天体物理 · 物理学 2023-10-17 Kyle Massingill , Brian Mason , Mark Lacy , Bjorn H. C. Emonts , Ilsang Yoon , Jianrui Li , Craig Sarazin
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