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Redundancies and correlations in the responses of sensory neurons seem to waste neural resources but can carry cues about structured stimuli and may help the brain to correct for response errors. To assess how the retina negotiates this…

神经元与认知 · 定量生物学 2014-03-05 K. D. Simmons , J. S. Prentice , G. Tkacik , J. Homann , H. K. Yee , S. E. Palmer , P. C. Nelson , V. Balasubramanian

We show that the unavoidable increase in neuronal response latency to ongoing stimulation serves as a nonuniform gradual stretching of neuronal circuit delay loops and emerges as an essential mechanism in the formation of various types of…

神经元与认知 · 定量生物学 2012-12-07 Roni Vardi , Reut Timor , Shimon Marom , Moshe Abeles , Ido Kanter

Two recent experimental observations pose a challenge to many cortical models. First, the activity in the auditory cortex is sparse, and firing rates can be described by a lognormal distribution. Second, the distribution of non-zero…

神经元与认知 · 定量生物学 2008-09-10 Alexei Koulakov , Tomas Hromadka , Anthony M. Zador

Neural networks encode information through their collective spiking activity in response to external stimuli. This population response is noisy and strongly correlated, with complex interplay between correlations induced by the stimulus,…

神经元与认知 · 定量生物学 2022-11-28 Gabriel Mahuas , Olivier Marre , Thierry Mora , Ulisse Ferrari

Cognitive function is driven by dynamic interactions between large-scale neural circuits or networks, enabling behavior. Fundamental principles constraining these dynamic network processes have remained elusive. Here we use network control…

神经元与认知 · 定量生物学 2015-10-28 Shi Gu , Fabio Pasqualetti , Matthew Cieslak , Scott T. Grafton , Danielle S. Bassett

Simultaneously recorded neurons exhibit correlations whose underlying causes are not known. Here, we use a population of threshold neurons receiving correlated inputs to model neural population recordings. We show analytically that small…

神经元与认知 · 定量生物学 2010-09-20 Jakob H Macke , Manfred Opper , Matthias Bethge

There are several indications that brain is organized not on a basis of individual unreliable neurons, but on a micro-circuital scale providing Lego blocks employed to create complex architectures. At such an intermediate scale, the firing…

神经与进化计算 · 计算机科学 2017-02-27 Ramin M. Hasani , Giorgio Ferrari , Hideaki Yamamoto , Sho Kono , Koji Ishihara , Soya Fujimori , Takashi Tanii , Enrico Prati

Several experiments and models have highlighted the importance of neuronal heterogeneity in brain dynamics and function. However, how such a cell-to-cell diversity can affect cortical computation, synchronization, and neuronal communication…

神经元与认知 · 定量生物学 2021-04-07 Katiele V. P. Brito , Fernanda Selingardi Matias

Sparse random networks contain structures that can be considered as diluted feed-forward networks. Modeling of cortical circuits has shown that feed-forward structures, if strongly pronounced compared to the embedding random network, enable…

神经元与认知 · 定量生物学 2013-08-16 Sven Jahnke , Marc Timme , Raoul-Martin Memmesheimer

Does synchronization between action potentials from different neurons in the visual system play a substantial role in solving the binding problem? The binding problem can be studied quantitatively in the broader framework of the information…

生物物理 · 物理学 2007-05-23 Simon R. Schultz , Huw D. R. Golledge , Stefano Panzeri

Zero-lag synchronization between distant cortical areas has been observed in a diversity of experimental data sets and between many different regions of the brain. Several computational mechanisms have been proposed to account for such…

神经元与认知 · 定量生物学 2014-05-07 Leonardo L. Gollo , Claudio Mirasso , Olaf Sporns , Michael Breakspear

Recent studies have shown how spiking networks can learn complex functionality through error-correcting plasticity, but the resulting structures and dynamics remain poorly studied. To elucidate how these models may link to observed dynamics…

神经元与认知 · 定量生物学 2025-08-19 Jonas Oberste-Frielinghaus , Anno C. Kurth , Julian Göltz , Laura Kriener , Junji Ito , Mihai A. Petrovici , Sonja Grün

Positive correlations in the activity of neurons are widely observed in the brain. Previous studies have shown these correlations to be detrimental to the fidelity of population codes or at best marginally favorable compared to independent…

神经元与认知 · 定量生物学 2013-07-22 Rava Azeredo da Silveira , Michael J. Berry

All higher order central nervous systems exhibit spontaneous neural activity, though the purpose and mechanistic origin of such activity remains poorly understood. We explore the ignition and spread of collective spontaneous…

神经元与认知 · 定量生物学 2010-04-14 Michael I. Ham , Vadas Gintautas , Guenter W. Gross

Identifying the spatio-temporal network structure of brain activity from multi-neuronal data streams is one of the biggest challenges in neuroscience. Repeating patterns of precisely timed activity across a group of neurons is potentially…

神经元与认知 · 定量生物学 2009-03-03 Casey Diekman , Kohinoor Dasgupta , Vijay Nair , P. S. Sastry , K. P. Unnikrishnan

Links in many real-world networks activate and deactivate in correspondence to the sporadic interactions between the elements of the system. The activation patterns may be irregular or bursty and play an important role on the dynamics of…

物理与社会 · 物理学 2017-02-03 Oriol Artime , Jose J. Ramasco , Maxi San Miguel

Neural activity exhibits a vast range of timescales that can be several fold larger than the membrane time constant of individual neurons. Two types of mechanisms have been proposed to explain this conundrum. One possibility is that large…

神经元与认知 · 定量生物学 2019-03-26 Manuel Beiran , Srdjan Ostojic

Neural correlations play a critical role in sensory information coding. They are of two kinds: signal correlations, when neurons have overlapping sensitivities, and noise correlations from network effects and shared noise. In experiments…

神经元与认知 · 定量生物学 2025-07-03 Gabriel Mahuas , Thomas Buffet , Olivier Marre , Ulisse Ferrari , Thierry Mora

Cortical circuits exhibit high levels of response diversity, even across apparently uniform neuronal populations. While emerging data-driven approaches exploit this heterogeneity to infer effective models of cortical circuit computation…

神经元与认知 · 定量生物学 2025-11-06 Mohammadreza Soltanipour , Stefan Treue , Fred Wolf

The computation performed by a neuron can be formulated as a combination of dimensional reduction in stimulus space and the nonlinearity inherent in a spiking output. White noise stimulus and reverse correlation (the spike-triggered average…

生物物理 · 物理学 2007-05-23 Blaise Aguera y Arcas , Adrienne Fairhall