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Multivariate meta-analysis (MMA) is a powerful tool for jointly estimating multiple outcomes' treatment effects. However, the validity of results from MMA is potentially compromised by outcome reporting bias (ORB), or the tendency for…

应用统计 · 统计学 2021-10-19 Ray Bai , Xiaokang Liu , Lifeng Lin , Yulun Liu , Stephen E. Kimmel , Haitao Chu , Yong Chen

Modeling uncertainty in deep neural networks, despite recent important advances, is still an open problem. Bayesian neural networks are a powerful solution, where the prior over network weights is a design choice, often a normal…

机器学习 · 统计学 2019-10-29 Raanan Y. Rohekar , Yaniv Gurwicz , Shami Nisimov , Gal Novik

Estimating model parameters of a general family of cure models is always a challenging task mainly due to flatness and multimodality of the likelihood function. In this work, we propose a fully Bayesian approach in order to overcome these…

统计方法学 · 统计学 2024-08-20 Panagiotis Papastamoulis , Fotios Milienos

Evaluating and tracking patients' functional status through the post-acute care continuum requires a common instrument. However, different post-acute service providers such as nursing homes, inpatient rehabilitation facilities and home…

统计方法学 · 统计学 2020-01-22 Chenyang Gu , Roee Gutman

The analysis of large-scale datasets, especially in biomedical contexts, frequently involves a principled screening of multiple hypotheses. The celebrated two-group model jointly models the distribution of the test statistics with mixtures…

统计方法学 · 统计学 2023-03-10 Francesco Denti , Stefano Peluso , Michele Guindani , Antonietta Mira

Bayesian hierarchical models are commonly employed for inference in count datasets, as they account for multiple levels of variation by incorporating prior distributions for parameters at different levels. Examples include Beta-Binomial,…

统计方法学 · 统计学 2024-11-04 Yuexi Wang , Nicholas G. Polson

We propose a Bayesian approach for both medical inquiry and disease inference, the two major phases in differential diagnosis. Unlike previous work that simulates data from given probabilities and uses ML algorithms on them, we directly use…

人工智能 · 计算机科学 2021-10-26 Hong Guan , Chitta Baral

Reliability in Neural Networks (NNs) is crucial in safety-critical applications like healthcare, and uncertainty estimation is a widely researched method to highlight the confidence of NNs in deployment. In this work, we propose an…

机器学习 · 计算机科学 2020-11-20 Utkarsh Sarawgi , Wazeer Zulfikar , Rishab Khincha , Pattie Maes

Accurate estimation of disease prevalence is essential for guiding public health strategies. Imperfect diagnostic tests can cause misclassification errors-false positives (FP) and false negatives (FN)-that may skew estimates if unaddressed.…

As modern neural networks get more complex, specifying a model with high predictive performance and sound uncertainty quantification becomes a more challenging task. Despite some promising theoretical results on the true posterior…

机器学习 · 计算机科学 2025-06-18 Alisa Sheinkman , Sara Wade

Joint training of speech enhancement model (SE) and speech recognition model (ASR) is a common solution for robust ASR in noisy environments. SE focuses on improving the auditory quality of speech, but the enhanced feature distribution is…

音频与语音处理 · 电气工程与系统科学 2022-04-04 Tianrui Wang , Weibin Zhu , Yingying Gao , Junlan Feng , Shilei Zhang

We consider compartmental models of communicable disease with uncertain contact rates. Stochastic fluctuations are often added to the contact rate to account for uncertainties. White noise, which is the typical choice for the fluctuations,…

种群与进化 · 定量生物学 2024-06-07 Konstantinos Mamis , Mohammad Farazmand

While observational data are routinely used to estimate causal effects of biomedical treatments, doing so requires special methods to adjust for observed confounding. These methods invariably rely on untestable statistical and causal…

统计方法学 · 统计学 2026-03-02 Arman Oganisian

Machine learning techniques typically rely on large datasets to create accurate classifiers. However, there are situations when data is scarce and expensive to acquire. This is the case of studies that rely on state-of-the-art computational…

机器学习 · 计算机科学 2019-10-02 Francisco Sahli Costabal , Paris Perdikaris , Ellen Kuhl , Daniel E. Hurtado

We investigate the asymptotic properties of Bayesian bivariate causal discovery for Gaussian Linear Structural Equation Models (SEMs) with heteroscedastic noise. We demonstrate that with purely observational data, the posterior distribution…

统计理论 · 数学 2026-03-30 Valentinian Lungu , Anish Dhir , Mark van der Wilk , Ioannis Kontoyiannis

We investigate predictions of stochastic compartmental models on the severity of disease outbreaks. The models we consider are the Susceptible-Infected-Susceptible (SIS) for bacterial infections, and the Susceptible -Infected-Removed (SIR)…

定量方法 · 定量生物学 2025-04-21 Sunia Tanweer , Konstantinos Mamis , Firas A. Khasawneh

It is increasingly common to collect data of multiple different types on the same set of samples. Our focus is on studying relationships between such multiview features and responses. A motivating application arises in the context of…

机器学习 · 统计学 2026-01-26 Niccolo Anceschi , Federico Ferrari , David B. Dunson , Himel Mallick

Bayesian inference methods are useful in infectious diseases modeling due to their capability to propagate uncertainty, manage sparse data, incorporate latent structures, and address high-dimensional parameter spaces. However, parameter…

统计方法学 · 统计学 2025-04-29 Xiahui Li , Fergus Chadwick , Ben Swallow

Multimodal models play a key role in empathy detection, but their performance can suffer when modalities provide conflicting cues. To understand these failures, we examine cases where unimodal and multimodal predictions diverge. Using…

计算与语言 · 计算机科学 2025-11-12 Maya Srikanth , Run Chen , Julia Hirschberg

Acute infection, if not rapidly and accurately detected, can lead to sepsis, organ failure and even death. Current detection of acute infection as well as assessment of a patient's severity of illness are imperfect. Characterization of a…