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Several centimeters below the skin lie multiple biomarkers, such as glucose, oxygenation, and blood flow. Monitoring these biomarkers regularly and in a non-invasive manner would enable early insight into metabolic status and vascular…

医学物理 · 物理学 2025-10-30 Talia Xu , Caitlin Smith , Charles Lo , Jami Shepherd , Gijs van Soest , Marco Zuniga

Atomic Force Microscopy - Infrared (AFM-IR) has emerged as a useful technique for measuring absorption spectra with spatial resolution better than the optical diffraction limit. The technique relies on the movement of a probe for atomic…

应用物理 · 物理学 2024-01-17 Luca Quaroni

Quantum sensors based on atom interferometers are advancing both fundamental physics and practical applications, with higher sensitivity being a key requirement for these investigations. Here, we experimentally demonstrate a sensitivity…

原子物理 · 物理学 2025-07-01 Sotatsu Otabe , Naoki Kaku , Tomoya Sato , Martin Miranda , Takuya Kawasaki , Mikio Kozuma

Photoacoustic(PA) imaging is a non-destructive and non-invasive technology for visualizing minute blood vessel structures in the body using ultrasonic sensors. In PA imaging, the image quality of a single-shot image is poor, and it is…

计算机视觉与模式识别 · 计算机科学 2025-02-11 Tatsuhiro Eguchi , Shumpei Takezaki , Mihoko Shimano , Takayuki Yagi , Ryoma Bise

Photoacoustic imaging systems offer a platform with high resolution to explore body tissues, food, and artwork. On the other hand, plasmonics constitutes a source of resonant heating and thermal expansion to generate acoustic waves.…

应用物理 · 物理学 2022-08-29 Ricardo Martín Abraham-Ekeroth

The Michelson interferometer is a cornerstone of experimental physics. Its applications range from providing first impressions of wave interference in educational settings to probing spacetime at minuscule precision scales. Interferometer…

仪器与探测器 · 物理学 2022-11-09 Lee McCuller

Resonant frequency modulation spectroscopy has been previously used as a highly-sensitive method for measuring the output of cold atom interferometers. Using a detailed model that accounts for optical saturation, laser intensities and…

原子物理 · 物理学 2024-12-11 Ryan J. Thomas , Samuel R. Legge , Simon A. Haine , John D. Close

Concatenated modal interferometers based multipoint sensing system for detection of instantaneous amplitude, frequency, and phase of mechanical vibrations is proposed and demonstrated. The sensor probes are fabricated using identical…

仪器与探测器 · 物理学 2021-05-17 Kalipada Chatterjee , Venugopal Arumuru , Dhananjay Patil , Rajan Jha

Hyperspectroscopy is a new method of surface image taking, providing simultaneously high position and spectral resolutions which allow one to make some conclusions about chemical compositions of the surfaces. We are now studying…

仪器与探测器 · 物理学 2016-11-18 I. Rodionov , J-M. Bidault , I. Crotty , P. Fonte , F. Galy , V. Peskov , O. Zanette

In recent years, photoacoustics has attracted intensive research for both anatomical and functional biomedical imaging. However, the physical interaction between photoacoustic generated endogenous waves and an exogenous ultrasound wave is a…

光学 · 物理学 2016-01-22 Fei Gao , Xiaohua Feng , Yuanjin Zheng , Claus-Dieter Ohl

We demonstrate a 13-fold speed improvement in broadband cantilever-enhanced photoacoustic spectroscopy (CEPAS) by combining it with phase-controlled Fourier-transform spectroscopy (PC-FTS) instead of traditional Fourier-transform infrared…

光学 · 物理学 2022-12-21 Santeri Larnimaa , Mikhail Roiz , Markku Vainio

The sensitivity in optical interferometry is strongly affected by losses during the signal propagation or at the detection stage. The optimal quantum states of the probing signals in the presence of loss were recently found. However, in…

Optical phase determination is an important and established tool in diverse fields such as astronomy, biology, or quantum optics. There is increasing interest in using a lower number of total photons. However, different noise sources, such…

量子物理 · 物理学 2024-02-21 Q. Pears Stefano , A. G. Magnoni , D. Rodrigues , J. Tiffenberg , C. Iemmi

Plasmonic sensing is an established technology for real-time biomedical diagnostics and air-quality monitoring. While intensity and wavelength tracking are the most commonly used interrogation methods for Surface Plasmon Resonance (SPR),…

Arterial Blood Pressure wave monitoring is considered to be important in assessment of cardiovascular system. We developed a novel pulse wave detection system using low frequency specific piezoelectric material as pressure wave sensor. The…

医学物理 · 物理学 2007-05-23 Shantanu Sur , S. K. Ghatak

Photoacoustic imaging has shown great promise for medical imaging, where optical energy absorption by blood haemoglobin is used as the contrast mechanism. A numerical method was developed for the in-silico assessment of the photoacoustic…

医学物理 · 物理学 2015-12-22 Kamyar Firouzi , Nader Saffari

Photoacoustic imaging of interphalangeal peripheral joints is of interest in the context of using the synovial membrane as a surrogate marker of rheumatoid arthritis. Previous work has shown that ultrasound produced by absorption of light…

医学物理 · 物理学 2015-06-09 Samir Biswas , Peter van Es , Wiendelt Steenbergen , Srirang Manohar

Squeezed vacuum states are now employed in gravitational-wave interferometric detectors, enhancing their sensitivity and thus enabling richer astrophysical observations. In future observing runs, the detectors will incorporate a filter…

天体物理仪器与方法 · 物理学 2022-07-13 Dhruva Ganapathy , Victoria Xu , Wenxuan Jia , Chris Whittle , Maggie Tse , Lisa Barsotti , Matthew Evans , Lee McCuller

We report multipass broadband photoacoustic spectroscopy of trace gases in the mid-infrared. The measurement principle of the sensor relies on supercontinuum-based Fourier transform photoacoustic spectroscopy (FT-PAS), in which a scanning…

仪器与探测器 · 物理学 2022-08-31 Tommi Mikkonen , Tuomas Hieta , Goëry Genty , Juha Toivonen

Phonon polaritons (PhPs), the collective phonon oscillations with hybridized electromagnetic fields, concentrate optical fields in the mid-infrared frequency range that matches the vibrational modes of molecules. The utilization of PhPs…

光学 · 物理学 2020-06-24 Haomin Wang , Eli Janzen , Le Wang , James H. Edgar , Xiaoji G. Xu