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Causal discovery problems use a set of observations to deduce causality between variables in the real world, typically to answer questions about biological or physical systems. These observations are often recorded at regular time…

信号处理 · 电气工程与系统科学 2026-02-24 Kurt Butler , Damian Machlanski , Panagiotis Dimitrakopoulos , Sotirios A. Tsaftaris

Investigating the relationship, particularly the lead-lag effect, between time series is a common question across various disciplines, especially when uncovering biological process. However, analyzing time series presents several…

统计方法学 · 统计学 2024-09-27 Wancen Mu , Jiawen Chen , Eric S. Davis , Kathleen Reed , Douglas Phanstiel , Michael I. Love , Didong Li

In healthcare, patient risk stratification models are often learned using time-series data extracted from electronic health records. When extracting data for a clinical prediction task, several formulations exist, depending on how one…

机器学习 · 计算机科学 2018-12-03 Eli Sherman , Hitinder Gurm , Ulysses Balis , Scott Owens , Jenna Wiens

Biological processes involve a variety of spatial and temporal scales. A holistic understanding of many biological processes therefore requires multi-scale models which capture the relevant properties on all these scales. In this manuscript…

分子网络 · 定量生物学 2015-06-23 Jan Hasenauer , Nick Jagiella , Sabrina Hross , Fabian J. Theis

With the advancement in the technology sector spanning over every field, a huge influx of information is inevitable. Among all the opportunities that the advancements in the technology have brought, one of them is to propose efficient…

信息检索 · 计算机科学 2021-12-14 Sudhanshu , Narinder Singh Punn , Sanjay Kumar Sonbhadra , Sonali Agarwal

This paper introduces a new unsupervised method for the clustering of physiological data into health states based on their similarity. We propose an iterative hierarchical clustering approach that combines health states according to a…

信号处理 · 电气工程与系统科学 2018-03-28 Fabian Schrumpf , Gerold Bausch , Matthias Sturm , Mirco Fuchs

Research into time series classification has tended to focus on the case of series of uniform length. However, it is common for real-world time series data to have unequal lengths. Differing time series lengths may arise from a number of…

机器学习 · 计算机科学 2019-10-11 Chang Wei Tan , Francois Petitjean , Eamonn Keogh , Geoffrey I. Webb

Temporal information conveyed by language describes how the world around us changes through time. Events, durations and times are all temporal elements that can be viewed as intervals. These intervals are sometimes temporally related in…

计算与语言 · 计算机科学 2012-03-23 Leon Derczynski , Robert Gaizauskas

We show how binary classification methods developed to work on i.i.d. data can be used for solving statistical problems that are seemingly unrelated to classification and concern highly-dependent time series. Specifically, the problems of…

机器学习 · 计算机科学 2013-06-10 Daniil Ryabko , Jérémie Mary

Many practical applications of AI in medicine consist of semi-supervised discovery: The investigator aims to identify features of interest at a resolution more fine-grained than that of the available human labels. This is often the scenario…

计算与语言 · 计算机科学 2020-04-08 Allen Schmaltz , Andrew Beam

Pain is a complex and pervasive condition that affects a significant portion of the population. Accurate and consistent assessment is essential for individuals suffering from pain, as well as for developing effective management strategies…

人工智能 · 计算机科学 2025-09-17 Stefanos Gkikas , Ioannis Kyprakis , Manolis Tsiknakis

Biomarker measurements can be relatively easy and quick to obtain and they are useful to investigate whether a compound works as intended on a mechanistic, pharmacological level. In some situations, it is realistic to assume that patients,…

统计方法学 · 统计学 2018-06-26 Björn Bornkamp , Georgina Bermann

Several application domains require formal but flexible approaches to the comparison problem. Different process models that cannot be related by behavioral equivalences should be compared via a quantitative notion of similarity, which is…

计算机科学中的逻辑 · 计算机科学 2010-06-29 Alessandro Aldini

Patient time series classification faces challenges in high degrees of dimensionality and missingness. In light of patient similarity theory, this study explores effective temporal feature engineering and reduction, missing value…

人工智能 · 计算机科学 2017-05-02 Mohammad Amin Morid , Olivia R. Liu Sheng , Samir Abdelrahman

Causality defines the relationship between cause and effect. In multivariate time series field, this notion allows to characterize the links between several time series considering temporal lags. These phenomena are particularly important…

统计方法学 · 统计学 2023-06-01 Antonin Arsac , Aurore Lomet , Jean-Philippe Poli

We propose a simple method to measure synchronization and time delay patterns between signals. It is based on the relative timings of events in the time series, defined e.g. as local maxima. The degree of synchronization is obtained from…

混沌动力学 · 物理学 2007-05-23 R. Quian Quiroga , T. Kreuz , P. Grassberger

Causal precedence between biochemical interactions is crucial in the biomedical domain, because it transforms collections of individual interactions, e.g., bindings and phosphorylations, into the causal mechanisms needed to inform…

计算与语言 · 计算机科学 2016-06-28 Gus Hahn-Powell , Dane Bell , Marco A. Valenzuela-Escárcega , Mihai Surdeanu

Time series classification (TSC) of biological signals has progressed from handcrafted, modality-specific approaches to deep architectures capable of representing the diverse waveform structures of underlying physiological processes (i.e.,…

Learning causal relationships from time series data is an important but challenging problem. Existing synthetic datasets often contain hidden artifacts that can be exploited by causal discovery methods, reducing their usefulness for…

机器学习 · 计算机科学 2026-03-23 Xiaoyu He , Petr Ryšavý , Jakub Mareček

The growing popularity of wearable sensors has generated large quantities of temporal physiological and activity data. Ability to analyze this data offers new opportunities for real-time health monitoring and forecasting. However, temporal…

信号处理 · 电气工程与系统科学 2021-06-02 Nazgol Tavabi , Kristina Lerman