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Traumatic brain injury (TBI) presents a significant public health challenge, often resulting in mortality or lasting disability. Predicting outcomes such as mortality and Functional Status Scale (FSS) scores can enhance treatment strategies…

The prediction and prevention of traumatic brain injury is a very important aspect of preventive medical science. This paper proposes a new coupled loading-rate hypothesis for the traumatic brain injury (TBI), which states that the main…

组织与器官 · 定量生物学 2008-11-18 Vladimir G. Ivancevic

Traumatic brain injury (TBI) is intrinsically heterogeneous, and typical clinical outcome measures like the Glasgow Coma Scale complicate this diversity. The large variability in severity and patient outcomes render it difficult to link…

Objective: Many recent studies have suggested that brain deformation resulting from a head impact is linked to the corresponding clinical outcome, such as mild traumatic brain injury (mTBI). Even though several finite element (FE) head…

The following study is motivated by experimental studies in traumatic brain injury (TBI). Recent research has demonstrated that low intensity non-impact blast wave exposure frequently leads to mild traumatic brain injury (mTBI); however,…

数值分析 · 数学 2018-04-24 Mauricio J. Del Razo , Randall J. LeVeque

Mild Traumatic Brain Injuries (mTBI) are caused by violent head motions or impacts. Most mTBI prevention strategies explicitly or implicitly rely on a "brain injury criterion". A brain injury criterion takes some descriptor of the head's…

医学物理 · 物理学 2022-01-19 Yang Wan , Alice Lux Fawzi , Haneesh Kesari

The mechanisms by which blast pressure waves cause mild to moderate traumatic brain injury (mTBI) are an open question. Possibilities include acceleration of the head, direct passage of the blast wave via the cranium, and propagation of the…

医学物理 · 物理学 2008-12-31 Amy Courtney , Michael Courtney

The discovery that repetitive mild traumatic brain injury (mTBI) can result in chronic traumatic encephalopathy (CTE) in high risk contact sports has led to increased scrutiny of head protective gear. In this work, we asked if it was…

Mild traumatic brain injuries (mTBI) are a highly prevalent condition with heterogeneous outcomes between individuals. A key factor governing brain tissue deformation and the risk of mTBI is the rotational kinematics of the head.…

Machine learning head models (MLHMs) are developed to estimate brain deformation for early detection of traumatic brain injury (TBI). However, the overfitting to simulated impacts and the lack of generalizability caused by distributional…

This report describes technical adaptations of a traumatic brain injury (TBI) model-largely inspired by Marmarou-in order to monitor microdialysis data and PtiO2 (brain tissue oxygen) before, during and after injury. We particularly…

Prognoses of Traumatic Brain Injury (TBI) outcomes are neither easily nor accurately determined from clinical indicators. This is due in part to the heterogeneity of damage inflicted to the brain, ultimately resulting in diverse and complex…

Patients with traumatic brain injury (TBI) often experience pathological increases in intracranial pressure (ICP), leading to intracranial hypertension (tIH), a common and serious complication. Early warning of an impending rise in ICP…

Traumatic brain injuries (TBI) are considered a silent epidemic. It affects many people, from automobiles to sports to service members. In this study, we employed a musculoskeletal head-neck model to understand the effect of impact…

组织与器官 · 定量生物学 2024-12-09 Rahid Zaman , Ashfaq Adnan

Traumatic Brain Injury (TBI) is a common cause of death and disability. However, existing tools for TBI diagnosis are either subjective or require extensive clinical setup and expertise. The increasing affordability and reduction in size of…

信号处理 · 电气工程与系统科学 2021-02-01 Navjodh Singh Dhillon , Agustinus Sutandi , Manoj Vishwanath , Miranda M. Lim , Hung Cao , Dong Si

Superelastic NiTi 1 shape memory alloy (SMA) wire was subjected to thermomechanical loading tests in tension to evaluate stress and temperature conditions under which the wire deforms plastically. Although the alloy demonstrated a very high…

材料科学 · 物理学 2024-06-24 P. Šittner , E. Iaparova , O. Molnárová , O. Tyc , X. Bian , L. Kadeřávek , L. Heller

Understanding the mechanical behavior of brain tissue is crucial for advancing both fundamental neuroscience and clinical applications. Yet, accurately measuring these properties remains challenging due to the brain unique mechanical…

Purpose: Computational head models are essential tools for studying the risk of mild traumatic brain injury (mTBI) under different activities and across populations. However, different computational models incorporate varied levels of…

组织与器官 · 定量生物学 2025-11-07 Anu Tripathi , Alison Brooks , Traci Snedden , Peter Ferrazzano , Christian Franck , Rika Wright Carlsen

In this paper, we introduce a new dataset in the medical field of Traumatic Brain Injury (TBI), called TBI-IT, which includes both electronic medical records (EMRs) and head CT images. This dataset is designed to enhance the accuracy of…

图像与视频处理 · 电气工程与系统科学 2024-03-15 Jie Li , Jiaying Wen , Tongxin Yang , Fenglin Cai , Miao Wei , Zhiwei Zhang , Li Jiang

Mechanical models of brain tissue are a beneficial tool to simulate neurosurgical interventions, disease progression, or brain development. However, the accuracy and predictive capacity of such a model relies on a precise experimental…

医学物理 · 物理学 2026-05-29 Laura Ruhland , Nina Reiter , Silvia Budday , Kai Willner