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Mechanical models of brain tissue are a beneficial tool to simulate neurosurgical interventions, disease progression, or brain development. However, the accuracy and predictive capacity of such a model relies on a precise experimental…

医学物理 · 物理学 2026-05-29 Laura Ruhland , Nina Reiter , Silvia Budday , Kai Willner

A longstanding challenge surrounding deep learning algorithms is unpacking and understanding how they make their decisions. Explainable Artificial Intelligence (XAI) offers methods to provide explanations of internal functions of algorithms…

人工智能 · 计算机科学 2022-08-16 Amin Nayebi , Sindhu Tipirneni , Brandon Foreman , Chandan K. Reddy , Vignesh Subbian

Artificial intelligence (AI) products can be trained to recognize tuberculosis (TB)-related abnormalities on chest radiographs. Various AI products are available commercially, yet there is lack of evidence on how their performance compared…

We present an algorithm for determining the acceleration field of a rigid body using measurements from four tri-axial accelerometers. The acceleration field is an important quantity in bio-mechanics problems, especially in the study of mild…

医学物理 · 物理学 2019-11-22 Mohammad Masiur Rahaman , Wenqiang Fang , Alice Lux Fawzi , Yang Wan , Haneesh Kesari

Computational biomechanics models of the brain have become an important tool for investigating the brain responses to mechanical loads. The geometry, loading conditions, and constitutive properties of such brain models are well-studied and…

计算工程、金融与科学 · 计算机科学 2025-12-10 Sajjad Arzemanzadeh , Benjamin Zwick , Karol Miller , Tim Rosenow , Stuart I. Hodgetts , Adam Wittek

Creating finite element models for simulation of bone behaviour, fracture occurrence and propagation requires feeding the system with adequate mechanical data. To date, little is known about the mechanical behaviour of long canine bones,…

Mild traumatic brain injury (mTBI) is a growing public health problem with an estimated incidence of one million people annually in US. Neurocognitive tests are used to both assess the patient condition and to monitor the patient progress.…

计算机视觉与模式识别 · 计算机科学 2018-02-16 Shervin Minaee , Siyun Wang , Yao Wang , Sohae Chung , Xiuyuan Wang , Els Fieremans , Steven Flanagan , Joseph Rath , Yvonne W. Lui

Wearable devices have been shown to effectively measure the head movement during impacts in sports like American football. When a head impact occurs, the device is triggered to collect and save the kinematic measurements during a predefined…

An analysis is presented of the applicability of the Kolsky technique for studying the high-rate deformation processes of structural materials under compression. Errors in the method caused by inertia and friction are estimated.…

应用物理 · 物理学 2020-08-20 Anatoly M. Bragov , Andrey K. Lomunov

Traumatic injuries are measured using the Abbreviated Injury Scale (AIS), which is a risk to life scale. New human computer models use stresses and strains to evaluate whether serious or fatal injuries are reached, unfortunately these…

组织与器官 · 定量生物学 2019-04-02 C. Bastien , C. Neal-Sturgess , J. Christensen , L. Wen

Cerebrovascular dynamics and pathomechanisms that evolve in the minutes and hours following traumatic vascular injury in the brain remain largely unknown. We investigated the pathophysiology evolution within the first three hours after…

Mild Traumatic Brain Injury (mTBI) is a common brain injury and affects a diverse group of people: soldiers, constructors, athletes, drivers, children, elders, and nearly everyone. Thus, having a well-established, fast, cheap, and accurate…

信号处理 · 电气工程与系统科学 2022-08-19 Weiqing Gu , Ryan Chang , Bohan Yang

Purpose: Computational head models are essential tools for studying the risk of mild traumatic brain injury (mTBI) under different activities and across populations. However, different computational models incorporate varied levels of…

组织与器官 · 定量生物学 2025-11-07 Anu Tripathi , Alison Brooks , Traci Snedden , Peter Ferrazzano , Christian Franck , Rika Wright Carlsen

Impact induced traumatic brain injury (ITBI) describes brain injury from head impact not necessarily accompanied by skull fracture. For sufficiently abrupt head impact decelerations, ITBI results from brain tissue stress incurred as the…

医学物理 · 物理学 2009-04-21 Eric G. Blackman

This research paper explores the impact of various input parameters, including Infill percentage, Layer Height, Extrusion Temperature, and Print Speed, on the resulting Tensile Strength in objects produced through additive manufacturing.…

机器学习 · 计算机科学 2023-05-31 Akshansh Mishra , Vijaykumar S Jatti

The accurate diagnosis and assessment of neurodegenerative disease and traumatic brain injuries (TBI) remain open challenges. Both cause cognitive and functional deficits due to focal axonal swellings (FAS), but it is difficult to deliver a…

神经元与认知 · 定量生物学 2016-12-15 Bethany Lusch , Jake Weholt , Pedro D. Maia , J. Nathan Kutz

A new apparatus and method is proposed for the investigation of material behavior under high-strain-rate tensile loads. We refer this apparatus as a Split Flying Bar. The method is based on using the inertia of a working mass attached to a…

经典物理 · 物理学 2012-01-05 Sergey Lopatnikov , Nikolas Shevchenko , John W. Gillespie

Mild Traumatic Brain Injury (mTBI) is a significant public health problem. The most troubling symptoms after mTBI are cognitive complaints. Studies show measurable differences between patients with mTBI and healthy controls with respect to…

图像与视频处理 · 电气工程与系统科学 2019-11-12 Tongda Xu , Xiyan Cai , Yao Wang , Xiuyuan Wang , Sohae Chung , Els Fieremans , Joseph Rath , Steven Flanagan , Yvonne W Lui

Brain injuries resulting from mechanical trauma represent an ongoing global public health issue. Several $\textit{in vitro}$ and $\textit{in vivo}$ models for traumatic brain injury (TBI) continue to be developed for delineating the various…

生物物理 · 物理学 2023-08-28 Yang Wan , Rafael D. González-Cruz , Diane Hoffman-Kim , Haneesh Kesari

Ischaemic stroke, a leading cause of death and disability, critically relies on neuroimaging for characterising the anatomical pattern of injury. Diffusion-weighted imaging (DWI) provides the highest expressivity in ischemic stroke but…