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Self-sustained activity in the brain is observed in the absence of external stimuli and contributes to signal propagation, neural coding, and dynamic stability. It also plays an important role in cognitive processes. In this work, by means…

A given neural network in the brain is involved in many different tasks. This implies that, when considering a specific task, the network's connectivity contains a component which is related to the task and another component which can be…

神经元与认知 · 定量生物学 2021-03-17 Friedrich Schuessler , Alexis Dubreuil , Francesca Mastrogiuseppe , Srdjan Ostojic , Omri Barak

Large bundles of myelinated axons, called white matter, anatomically connect disparate brain regions together and compose the structural core of the human connectome. We recently proposed a method of measuring the local integrity along the…

We consider a network of randomly coupled rate-based neurons influenced by external and internal noise. We derive a second-order stochastic mean-field model for the network dynamics and use it to analyze the stability and bifurcations in…

混沌动力学 · 物理学 2015-12-14 Vladimir Klinshov , Igor Franovic

Human brain contains about 10 billion neurons, each of which has about 10~10,000 nerve endings from which neurotransmitters are released in response to incoming spikes, and the released neurotransmitters then bind to receptors located in…

神经元与认知 · 定量生物学 2012-03-06 Xuejuan Zhang , Jianfeng Feng

Modelling the near-wall region of wall-bounded turbulent flows is a widespread practice to reduce the computational cost of large-eddy simulations (LESs) at high Reynolds number. As a first step towards a data-driven wall-model, a…

Criticality can be exactly demonstrated in certain models of brain activity, yet it remains challenging to identify in empirical data. We trained a fully connected deep neural network to learn the phases of an excitable model unfolding on…

神经元与认知 · 定量生物学 2022-06-13 Hernan Bocaccio , Enzo Tagliazucchi

Many recent efforts in computational modeling of macro-scale brain dynamics have begun to take a data-driven approach by incorporating structural and/or functional information derived from subject data. Here, we discuss recent work using…

神经元与认知 · 定量生物学 2018-11-15 Kanika Bansal , Johan Nakuci , Sarah Feldt Muldoon

Recent experimental advances are producing an avalanche of data on both neural connectivity and neural activity. To take full advantage of these two emerging datasets we need a framework that links them, revealing how collective neural…

神经元与认知 · 定量生物学 2020-02-27 Gabriel Koch Ocker , Krešimir Josić , Eric Shea-Brown , Michael A. Buice

Extended numerical simulations of threshold models have been performed on a human brain network with N=836733 connected nodes available from the Open Connectome project. While in case of simple threshold models a sharp discontinuous phase…

无序系统与神经网络 · 物理学 2016-12-28 Géza Ódor

We study the role of scale-free structure and noise in collective dynamics of neuronal networks. For this purpose, we simulate and study analytically a cortical circuit model with stochastic neurons. We compare collective neuronal activity…

无序系统与神经网络 · 物理学 2013-03-27 D. Holstein , A. V. Goltsev , J. F. F. Mendes

An essential step toward understanding neural circuits is linking their structure and their dynamics. In general, this relationship can be almost arbitrarily complex. Recent theoretical work has, however, begun to identify some broad…

神经元与认知 · 定量生物学 2017-03-10 Gabriel Koch Ocker , Yu Hu , Michael A. Buice , Brent Doiron , Krešimir Josić , Robert Rosenbaum , Eric Shea-Brown

Functional brain networks can change rapidly as a function of stimuli or cognitive shifts. Tracking dynamic functional connectivity is particularly challenging as it requires estimating the structure of the network at each moment as well as…

统计方法学 · 统计学 2024-04-30 Wan-Chi Hsin , Uri T. Eden , Emily P. Stephen

Functions of brain areas in complex animals are believed to rely on the dynamics of networks of neurons rather than on single neurons. On the other hand, the network dynamics reflect and arise from the integration and coordination of the…

神经元与认知 · 定量生物学 2017-01-03 Stefano Cavallari

The relative timing of action potentials in neurons recorded from local cortical networks often shows a non-trivial dependence, which is then quantified by cross-correlation functions. Theoretical models emphasize that such spike train…

神经元与认知 · 定量生物学 2017-06-28 Taskin Deniz , Stefan Rotter

The estimation of causal network architectures in the brain is fundamental for understanding cognitive information processes. However, access to the dynamic processes underlying cognition is limited to indirect measurements of the hidden…

神经元与认知 · 定量生物学 2020-08-17 H. C. Ruiz-Euler , H. J. Kappen

Researchers continue exploring neurons' intricate patterns of activity in the cerebral visual cortex in response to visual stimuli. The way neurons communicate and optimize their interactions with each other under different experimental…

神经元与认知 · 定量生物学 2024-02-09 Lauren Miako Beede , Giuseppe Vinci

Neural network oscillations are a fundamental mechanism for cognition, perception and consciousness. Consequently, perturbations of network activity play an important role in the pathophysiology of brain disorders. When structural…

神经元与认知 · 定量生物学 2016-04-29 Timothée Proix , Fabrice Bartolomei , Maxime Guye , Viktor K. Jirsa

Over the last years, increasing evidence has fuelled the hypothesis that Autism Spectrum Disorder (ASD) is a condition of altered brain functional connectivity. The great majority of these empirical studies rely on functional magnetic…

神经元与认知 · 定量生物学 2010-08-02 Pablo Barttfeld , Bruno Wicker , Sebastián Cukier , Silvana Navarta , Sergio Lew , Mariano Sigman

With our ability to record more neurons simultaneously, making sense of these data is a challenge. Functional connectivity is one popular way to study the relationship between multiple neural signals. Correlation-based methods are a set of…

神经元与认知 · 定量生物学 2017-06-09 Tiger W. Lin , Anup Das , Giri P. Krishnan , Maxim Bazhenov , Terrence J. Sejnowski