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In molecular phylogeny, relationships among organisms are reconstructed using DNA or protein sequences and are displayed as trees. A linear increase in the number of sequences results in an exponential increase of possible trees. Thus,…

基因组学 · 定量生物学 2007-05-23 Kerstin Hoef-Emden

Advances in molecular technologies underlie an enormous growth in the size of data sets pertaining to biology and biomedicine. These advances parallel those in the deep learning subfield of machine learning. Components in the differentiable…

定量方法 · 定量生物学 2024-06-14 Alex Jihun Lee , Reza Abbasi-Asl

The grand challenges in biology today are being shaped by powerful high-throughput technologies that have revealed the genomes of many organisms, global expression patterns of genes and detailed information about variation within…

统计理论 · 数学 2007-06-13 Lior Pachter , Bernd Sturmfels

New technologies have enabled the investigation of biology and human health at an unprecedented scale and in multiple dimensions. These dimensions include a myriad of properties describing genome, epigenome, transcriptome, microbiome,…

定量方法 · 定量生物学 2018-10-22 Marinka Zitnik , Francis Nguyen , Bo Wang , Jure Leskovec , Anna Goldenberg , Michael M. Hoffman

Microorganisms such as bacteria and fungi play essential roles in many application fields, like biotechnique, medical technique and industrial domain. Microorganism counting techniques are crucial in microorganism analysis, helping…

图像与视频处理 · 电气工程与系统科学 2021-09-30 Jiawei Zhang , Chen Li , Md Mamunur Rahaman , Yudong Yao , Pingli Ma , Jinghua Zhang , Xin Zhao , Tao Jiang , Marcin Grzegorzek

Molecular dynamics (MD) has become a powerful tool for studying biophysical systems, due to increasing computational power and availability of software. Although MD has made many contributions to better understanding these complex…

计算物理 · 物理学 2019-09-27 Yihang Wang , Joao Marcelo Lamim Ribeiro , Pratyush Tiwary

Data is crucial for machine learning (ML) applications, yet acquiring large datasets can be costly and time-consuming, especially in complex, resource-intensive fields like biopharmaceuticals. A key process in this industry is upstream…

机器学习 · 计算机科学 2025-06-23 Johnny Peng , Thanh Tung Khuat , Katarzyna Musial , Bogdan Gabrys

Molecular ecology uses molecular genetic data to answer traditional ecological questions in biogeography and biodiversity among others. Several ecological principles, such as the niche hypothesis and the competitive exclusions, are based on…

In post genomic era with the advent of new technologies a huge amount of complex molecular data are generated with high throughput. The management of this biological data is definitely a challenging task due to complexity and heterogeneity…

数据库 · 计算机科学 2014-03-13 Ananya Bose , Suprativ Saha

The study of microorganisms, or microbiology, has demonstrated significant development since its inception and is currently a key field of biological sciences that has a huge impact on modern society and scientific research. Over the…

生物物理 · 物理学 2025-05-16 Daniil S. Gerassimov

Motility is an essential factor for an organism's survival and diversification. With the advent of novel single-cell technologies, analytical frameworks and theoretical methods, we can begin to probe the complex lives of microscopic motile…

Traditionally, diagnosis and treatment of fungal infections in humans depend heavily on face-to-face consultations or examinations made by specialized laboratory scientists known as mycologists. In many cases, such as the recent…

图像与视频处理 · 电气工程与系统科学 2021-09-16 Camilo Javier Pineda Sopo , Farshid Hajati , Soheila Gheisari

Molecular and morphological characters, as important parts of biological taxonomy, are contradictory but need to be integrated. Organism's image recognition and bioinformatics are emerging and hot problems nowadays but with a gap between…

计算机视觉与模式识别 · 计算机科学 2022-06-29 Jiewen Xiao , Wenbin Liao , Ming Zhang , Jing Wang , Jianxin Wang , Yihua Yang

Network science has become an essential interdisciplinary tool for understanding complex biological systems. However, because these systems undergo continuous, often stimulus-driven changes in both structure and function, traditional static…

分子网络 · 定量生物学 2025-05-19 Abir Khazaal , Fatemeh Vafaee

Fungi undergo dynamic morphological transformations throughout their lifecycle, forming intricate networks as they transition from spores to mature mycelium structures. To support the study of these time-dependent processes, we present a…

计算机视觉与模式识别 · 计算机科学 2025-01-07 A. Rani , D. O. Arroyo , P. Durdevic

Mathematical models are increasingly a part of microbiological research. Here, we share our perspective on how modeling advances the discipline by: (i) enforcing logical consistency, (ii) enabling quantitative prediction, (iii) extracting…

其他定量生物学 · 定量生物学 2026-04-22 Jamie A. Lopez , Amir Erez

Recent attacks of various viruses with having deep and extensive impact at a global scale has warranted that microbiome be studied extensively and in a robust analytic framework. Microbiome typically refers to the collective genomes of such…

应用统计 · 统计学 2023-03-30 M. Bhattacharjee

Advances in molecular biology are enabling rapid and efficient analyses for effective intervention in domains such as biology research, infectious disease management, food safety, and biodefense. The emergence of microfluidics and…

定量方法 · 定量生物学 2017-03-28 Harikrishnan Jayamohan , Valentin Romanov , Huizhong Li , Jiyoung Son , Raheel Samuel , John Nelson , Bruce Gale

The human microbiome is the ensemble of genes in the microbes that live inside and on the surface of humans. Because microbial sequencing information is now much easier to come by than phenotypic information, there has been an explosion of…

种群与进化 · 定量生物学 2014-07-08 Frederick A Matsen

As sequencing technologies become more affordable and genomic databases expand continuously, the reuse of publicly available sequencing data emerges as a powerful strategy for studying microbial pathogens. Indeed, raw sequencing reads…

定量方法 · 定量生物学 2025-05-16 Damien Richard , Nils Poulicard
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