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We demonstrate that powder diffraction data can be collected from sub-micron crystals of a mbrane protein with nearly two orders of magnitude more atoms than the molecules commonly used for powder diffraction. The crystals of photosystem-1…

Monitoring the kinetics and conformational dynamics of single enzymes is crucial in order to better understand their biological functions as these motions and structural dynamics are usually unsynchronized among the molecules. Detecting the…

生物物理 · 物理学 2017-05-29 Eugene Kim , Martin D. Baaske , Isabel Schuldes , Peter S. Wilsch , Frank Vollmer

Using Brownian dynamics simulations, we study the migration of long charged chains in an electrophoretic microchannel device consisting of an array of microscopic entropic traps with alternating deep regions and narrow constrictions. Such a…

生物物理 · 物理学 2007-05-23 Martin Streek , Friederike Schmid , Thanh Tu Duong , Alexandra Ros

Myosin motor proteins drive vigorous steady-state fluctuations in the actin cytoskeleton of cells. Endogenous embedded semiflexible filaments such as microtubules, or added filaments such as single-walled carbon nanotubes are used as novel…

生物物理 · 物理学 2016-06-21 J. Gladrow , N. Fakhri , F. C. MacKintosh , C. F. Schmidt , C. P. Broedersz

Concomitant amplified spontaneous emission (ASE) and F\"orster resonance energy transfer (FRET) are investigated in electrospun light-emitting fibers. Upon dye-doping with a proper FRET couple system, free-standing fibrous mats exhibit…

Separation is a crucial step in the analysis of living microparticles. In particular, the selective microseparation of phytoplankton by size and shape remains an open problem, even though these criteria are essential for their gender and/or…

应用物理 · 物理学 2025-04-09 Nicolas Ruyssen , Bastien Oliva , Lylian Challier , Vincent Noël , Benjamin Rotenberg

Dynamical instrument limitations, such as finite detection bandwidth, do not simply add statistical errors to fluctuation measurements, but can create significant systematic biases that affect the measurement of steady-state properties.…

生物物理 · 物理学 2010-01-18 Wesley P. Wong , Ken Halvorsen

The recent breakthrough of AlphaFold3 in modeling complex biomolecular interactions, including those between proteins and ligands, nucleotides, or metal ions, creates new opportunities for protein design. In so-called inverse protein…

生物大分子 · 定量生物学 2025-07-22 Kai Yi , Kiarash Jamali , Sjors H. W. Scheres

Recording the fluorescence of a magneto-optical trap (MOT) is a standard tool for measuring atom numbers in experiments with ultracold atoms. When trapping few atoms in a small MOT, the emitted fluorescence increases with the atom number in…

量子气体 · 物理学 2021-03-17 Martin Schlederer , Alexandra Mozdzen , Thomas Lompe , Henning Moritz

We propose a new type of optical switch based on a ferroelectric. It is based on the gap which exists for waves propagating from a dielectric to a ferroelectric material. This gap depends on the polarization of the ferroelectric. We show…

光学 · 物理学 2015-06-11 J. -G. Caputo , A. I. Maimistov , E. V. Kazantseva

Time-bin encoded photon pairs enable robust, decoherence-resistant transmission through optical fibers for long-distance quantum communication, where phase noise poses a critical limitation to stable operation. Here, we implement an…

量子物理 · 物理学 2025-10-28 P. M. Berto , F. CampodÓnico , A. A. Matoso , S. Vergara , P. A. Coelho , G. Lima , S. PÁdua , J. CariÑe

An antiproton plasma confined in a quasi-1D device is described in terms of a self-consistent fluid formulation using a variational approach. Unlike previous treatments, the use of the time-dependent variational method allows to retain the…

等离子体物理 · 物理学 2024-06-19 Luiz Gustavo F. Soares , Fernando Haas

The influence of microscopic force fields on the motion of Brownian particles plays a fundamental role in a broad range of fields, including soft matter, biophysics, and active matter. Often, the experimental calibration of these force…

计算物理 · 物理学 2020-06-17 Aykut Argun , Tobias Thalheim , Stefano Bo , Frank Cichos , Giovanni Volpe

We demonstrate that a set of microfabricated electrodes can be coupled to a commercial optical tweezers device, implementing a hybrid electro-optical trap with multiple functionalities to manipulate micro/nanoparticles in suspension. Our…

We measure the AC-Stark shifts of the 5S{1/2}, F=2 to 5P{3/2}, F'=3 transitions of individual optically trapped 87Rb atoms using a non-destructive detection technique that allows us to measure the fluorescent signal of one-and-the-same atom…

原子物理 · 物理学 2015-06-15 Chung-Yu Shih , Michael S. Chapman

Using a Josephson junction interferometer (DC SQUID) as a microwave source for irradiating a single-electron trap, both devices fabricated on the same chip, we study the process of photon-assisted tunneling as an effective mechanism of…

超导电性 · 物理学 2016-04-27 Servey V. Lotkhov , Behdad Jalali-Jafari , Alexander B. Zorin

We introduce a simple approach to fabricate aligned carbon nanotube (ACNT) device for broadband polarization control in fiber laser systems. The ACNT device was fabricated by pulling from as-fabricated vertically-aligned carbon nanotube…

Suspensions of anisotropic Brownian particles are commonly encountered in a wide array of applications such as drug delivery and manufacturing of fiber-reinforced composites. Technological applications and fundamental studies of small…

软凝聚态物质 · 物理学 2019-11-19 Dinesh Kumar , Anish Shenoy , Songsong Li , Charles M. Schroeder

We present a novel experimental setup in which magnetic and optical tweezers are combined for torque and force transduction onto single filamentous molecules in a transverse configuration to allow simultaneous mechanical measurement and…

生物大分子 · 定量生物学 2015-06-24 Zhaokun Zhou , Helen Miller , Adam J. M. Wollman , Mark C. Leake

The magnetic anisotropy of a FeCuNbSiB (Finemet) film deposited on Kapton has been studied by micro-strip ferromagnetic resonance technique. We have shown that the flexibility of the substrate allows a good transmission of elastic strains…