相关论文: Biases in the Experimental Annotations of Protein …

Protein quantification and analysis are well-accepted approaches for biomarker discovery but are limited to identification without structural information. High-throughput omics data (i.e., genomics, transcriptomics, and proteomics) have…

We are now witnessing significant progress of deep learning methods in a variety of tasks (or datasets) of proteins. However, there is a lack of a standard benchmark to evaluate the performance of different methods, which hinders the…

Automated fact-checking based on machine learning is a promising approach to identify false information distributed on the web. In order to achieve satisfactory performance, machine learning methods require a large corpus with reliable…

Large annotated datasets have been a key component in the success of deep learning. However, annotating medical images is challenging as it requires expertise and a large budget. In particular, annotating different types of cells in…

Majority voting and averaging are common approaches employed to resolve annotator disagreements and derive single ground truth labels from multiple annotations. However, annotators may systematically disagree with one another, often…

Purpose The purpose of this paper is to explore which structures of academic articles referees would pay more attention to, what specific content referees focus on, and whether the distribution of PRC is related to the citations.…

The constant development of new data analysis methods in many fields of research is accompanied by an increasing awareness that these new methods often perform better in their introductory paper than in subsequent comparison studies…

Proteins are biomolecules of life. They fold into a great variety of three-dimensional (3D) shapes. Underlying these folding patterns are many recurrent structural fragments or building blocks (analogous to `LEGO bricks'). This paper…

For many structured learning tasks, the data annotation process is complex and costly. Existing annotation schemes usually aim at acquiring completely annotated structures, under the common perception that partial structures are of low…

Recent advances in large language models (LLMs) have highlighted the effectiveness of chain-of-thought reasoning in symbolic domains such as mathematics and programming. However, our study shows that directly transferring such text-based…

The increasing integration of machine learning algorithms in daily life underscores the critical need for fairness and equity in their deployment. As these technologies play a pivotal role in decision-making, addressing biases across…

Motivation: In recent years, protein function prediction has broken through the bottleneck of sequence features, significantly improving prediction accuracy using high-precision protein structures predicted by AlphaFold2. While…

The NLP community has long advocated for the construction of multi-annotator datasets to better capture the nuances of language interpretation, subjectivity, and ambiguity. This paper conducts a retrospective study to show how performance…

In recent years, progress in NLU has been driven by benchmarks. These benchmarks are typically collected by crowdsourcing, where annotators write examples based on annotation instructions crafted by dataset creators. In this work, we…

AI systems depend on the invisible and undervalued labor of data workers, who are often treated as interchangeable units rather than collaborators with meaningful expertise. Critical scholars and practitioners have proposed alternative…

Bacteriophages are viruses that target bacteria, playing a crucial role in microbial ecology. Phage proteins are important in understanding phage biology, such as virus infection, replication, and evolution. Although a large number of new…

Performance metrics for medical image segmentation models are used to measure the agreement between the reference annotation and the predicted segmentation. Usually, overlap metrics, such as the Dice, are used as a metric to evaluate the…

The application of deep learning methods, particularly foundation models, in biological research has surged in recent years. These models can be text-based or trained on underlying biological data, especially omics data of various types.…

Proteins employ the information stored in the genetic code and translated into their sequences to carry out well-defined functions in the cellular environment. The possibility to encode for such functions is controlled by the balance…

In recent years, machine learning has been proposed as a promising strategy to build accurate scoring functions for computational docking finalized to numerically empowered drug discovery. However, the latest studies have suggested that…