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Cone-beam CT (CBCT)-based online adaptive radiotherapy calls for accurate auto-segmentation to reduce the time cost for physicians to edit contours. However, deep learning (DL)-based direct segmentation of CBCT images is a challenging task,…

医学物理 · 物理学 2023-02-22 Xiao Liang , Howard Morgan , Ti Bai , Michael Dohopolski , Dan Nguyen , Steve Jiang

Online adaptive radiation therapy (ART) promises the ability to deliver an optimal treatment in response to daily patient anatomic variation. A major technical barrier for the clinical implementation of online ART is the requirement of…

Computed tomography (CT) to cone-beam computed tomography (CBCT) deformable image registration (DIR) is a crucial step in adaptive radiation therapy. Current intensity-based registration algorithms, such as demons, may fail in the context…

医学物理 · 物理学 2017-08-23 Xin Zhen , Xuejun Gu , Hao Yan , Linghong Zhou , Xun Jia , Steve B. Jiang

Deformable image registration (DIR) is a crucial tool in radiotherapy for analyzing anatomical changes and motion patterns. Current DIR implementations rely on discrete volumetric motion representation, which often leads to compromised…

医学物理 · 物理学 2025-07-22 Xia Li , Runzhao Yang , Muheng Li , Xiangtai Li , Antony J. Lomax , Joachim M. Buhmann , Ye Zhang

Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans essential. Conventional DIR methods are often too slow for…

Background and Purpose: Voxel-based analysis (VBA) helps to identify dose-sensitive regions by aligning individual dose distributions within a common coordinate system (CCS). Accurate deformable image registration (DIR) is essential for…

医学物理 · 物理学 2025-09-26 Xingyue Ruan , Xia Li , Muheng Li , Barbara Bachtiary , Antony Lomax , Zhiling Chen , Ye Zhang

CBCTs in image-guided radiotherapy provide crucial anatomy information for patient setup and plan evaluation. Longitudinal CBCT image registration could quantify the inter-fractional anatomic changes. The purpose of this study is to propose…

图像与视频处理 · 电气工程与系统科学 2023-04-26 Huiqiao Xie , Yang Lei , Yabo Fu , Tonghe Wang , Justin Roper , Jeffrey D. Bradley , Pretesh Patel , Tian Liu , Xiaofeng Yang

Joint image registration and segmentation has long been an active area of research in medical imaging. Here, we reformulate this problem in a deep learning setting using adversarial learning. We consider the case in which fixed and moving…

图像与视频处理 · 电气工程与系统科学 2019-07-01 Mohamed S. Elmahdy , Jelmer M. Wolterink , Hessam Sokooti , Ivana Išgum , Marius Staring

Objective: Quantify geometric and dosimetric accuracy of a novel prostate MR-to-MR deformable image registration (DIR) approach to support MR-guided adaptive radiation therapy dose accumulation. Approach: We evaluated DIR accuracy in 25…

This paper aims to create a deep learning framework that can estimate the deformation vector field (DVF) for directly registering abdominal MRI-CT images. The proposed method assumed a diffeomorphic deformation. By using topology-preserved…

计算机视觉与模式识别 · 计算机科学 2024-05-07 Yang Lei , Luke A. Matkovic , Justin Roper , Tonghe Wang , Jun Zhou , Beth Ghavidel , Mark McDonald , Pretesh Patel , Xiaofeng Yang

Background: Voxel-based analysis (VBA) for population level radiotherapy (RT) outcomes modeling requires topology preserving inter-patient deformable image registration (DIR) that preserves tumors on moving images while avoiding unrealistic…

图像与视频处理 · 电气工程与系统科学 2024-11-28 Jue Jiang , Chloe Min Seo Choi , Maria Thor , Joseph O. Deasy , Harini Veeraraghavan

Adaptive radiotherapy (ART), especially online ART, effectively accounts for positioning errors and anatomical changes. One key component of online ART is accurately and efficiently delineating organs at risk (OARs) and targets on online…

Deformable Image Registration (DIR) is essential for aligning medical images that exhibit anatomical variations, facilitating applications such as disease tracking and radiotherapy planning. While classical iterative methods and deep…

计算机视觉与模式识别 · 计算机科学 2025-09-08 Jihe Li , Xiang Liu , Fabian Zhang , Xia Li , Xixin Cao , Ye Zhang , Joachim Buhmann

Deformable Image Registration (DIR) of MR and CT images is one of the most challenging registration task, due to the inherent structural differences of the modalities and the missing dense ground truth. Recently cycle Generative Adversarial…

计算机视觉与模式识别 · 计算机科学 2018-07-20 Christine Tanner , Firat Ozdemir , Romy Profanter , Valeriy Vishnevsky , Ender Konukoglu , Orcun Goksel

The accuracy of deformable image registration (DIR) has a significant dosimetric impact in radiation treatment planning. We evaluated accuracy of various DIR algorithms using variations of the deformation point and volume. The reference…

The purpose of this study is to develop a deep learning based method that can automatically generate segmentations on cone-beam CT (CBCT) for head and neck online adaptive radiation therapy (ART), where expert-drawn contours in planning CT…

医学物理 · 物理学 2021-02-02 Xiao Liang , Howard Morgan , Dan Nguyen , Steve Jiang

Deformable image registration between Computed Tomography (CT) images and Magnetic Resonance (MR) imaging is essential for many image-guided therapies. In this paper, we propose a novel translation-based unsupervised deformable image…

图像与视频处理 · 电气工程与系统科学 2020-09-22 Zhe Xu , Jie Luo , Jiangpeng Yan , Ritvik Pulya , Xiu Li , William Wells , Jayender Jagadeesan

Accurate registration of medical images is vital for doctor's diagnosis and quantitative analysis. In this paper, we propose a new deformable medical image registration method based on average geometric transformations and VoxelMorph CNN…

计算机视觉与模式识别 · 计算机科学 2019-07-24 Yongpei Zhu , Zicong Zhou , Guojun Liao , Kehong Yuan

Image registration aims to establish spatial correspondence across pairs, or groups of images, and is a cornerstone of medical image computing and computer-assisted-interventions. Currently, most deep learning-based registration methods…

图像与视频处理 · 电气工程与系统科学 2021-07-12 Xiang Chen , Nishant Ravikumar , Yan Xia , Alejandro F Frangi

Medical image registration is one of the key processing steps for biomedical image analysis such as cancer diagnosis. Recently, deep learning based supervised and unsupervised image registration methods have been extensively studied due to…

计算机视觉与模式识别 · 计算机科学 2019-07-03 Boah Kim , Jieun Kim , June-Goo Lee , Dong Hwan Kim , Seong Ho Park , Jong Chul Ye
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