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Computer-aided design for synthetic biology promises to accelerate the rational and robust engineering of biological systems; it requires both detailed and quantitative mathematical and experimental models of the processes to (re)design,…

Coreset, which is a summary of the original dataset in the form of a small weighted set in the same sample space, provides a promising approach to enable machine learning over distributed data. Although viewed as a proxy of the original…

机器学习 · 计算机科学 2020-06-24 Hanlin Lu , Ming-Ju Li , Ting He , Shiqiang Wang , Vijaykrishnan Narayanan , Kevin S Chan

A probabilistic clustering algorithm is proposed for the analysis of forensic DNA mixtures in which individual cells are isolated and short tandem repeats are amplified using the polymerase chain reaction to generate single cell…

应用统计 · 统计学 2025-10-14 Robert G. Cowell

Semi-supervised clustering is a basic problem in various applications. Most existing methods require knowledge of the ideal cluster number, which is often difficult to obtain in practice. Besides, satisfying the must-link constraints is…

最优化与控制 · 数学 2025-03-07 Wei Liu , Xin Liu , Michael K. Ng , Zaikun Zhang

The Set Partitioning Problem is a combinatorial optimization problem with wide-ranging applicability, used to model various real-world tasks such as facility location and crew scheduling. However, real-world applications often require…

最优化与控制 · 数学 2025-03-24 Yasuyuki Ihara

Federated learning faces significant challenges in scenarios with heterogeneous data distributions and adverse network conditions, such as delays, packet loss, and data poisoning attacks. This paper proposes a novel method based on the…

机器学习 · 计算机科学 2025-01-28 Mohammad Ghabel Rahmat , Majid Khalilian

We propose a hybrid algorithm for the time integration of large sets of rate equations coupled by a relatively small number of degrees of freedom. A subset containing fast degrees of freedom evolves deterministically, while the rest of the…

材料科学 · 物理学 2015-06-16 Marco Gherardi , Thomas Jourdan , Solène Le Bourdiec , Guy Bencteux

Quantum computing (QC) has gained popularity due to its unique capabilities that are quite different from that of classical computers in terms of speed and methods of operations. This paper proposes hybrid models and methods that…

量子物理 · 物理学 2019-11-12 Akshay Ajagekar , Travis Humble , Fengqi You

We present an approach to model-based hierarchical clustering by formulating an objective function based on a Bayesian analysis. This model organizes the data into a cluster hierarchy while specifying a complex feature-set partitioning that…

机器学习 · 计算机科学 2013-01-18 Shivakumar Vaithyanathan , Byron E Dom

Modern algorithms for de novo prediction of protein structures typically output multiple full-length models (decoys) rather than a single solution. Subsequent clustering of such decoys is used both to gauge the success of the modelling and…

生物大分子 · 定量生物学 2017-12-12 Dmytro Guzenko , Sergei V. Strelkov

Correlation clustering is a concept of machine learning. The ultimate goal of such a clustering is to find a partition with minimal conflicts. In this paper we investigate a correlation clustering of integers, based upon the greatest common…

数论 · 数学 2014-04-04 L. Aszalós , L. Hajdu , A. Pethő

Hybrid modeling provides an effective solution to cope with multiple time scales dynamics in systems biology. Among the applications of this method, one of the most important is the cell cycle regulation. The machinery of the cell cycle,…

计算工程、金融与科学 · 计算机科学 2013-09-05 Vincent Noël , Sergey Vakulenko , Ovidiu Radulescu

Computational theory and practice generally focus on single-paradigm systems, but relatively little is known about how best to combine components based on radically different approaches (e.g., silicon chips and wetware) into a single…

新兴技术 · 计算机科学 2014-08-13 Marian Gheorghe , Mike Stannett

The ever higher complexity of manufacturing systems, continually shortening life cycles of products and their increasing variety, as well as the unstable market situation of the recent years require introducing grater flexibility and…

计算工程、金融与科学 · 计算机科学 2007-05-23 H. Tamaki , V. V. Kryssanov , S. Kitamura

Machine Learning (ML) models offer significant potential for advancing cell counting applications in neuroscience, medical research, pharmaceutical development, and environmental monitoring. However, implementing these models effectively…

This paper presents a distributed multi-robot printing method which utilizes an optimization approach to decompose and allocate a printing task to a group of mobile robots. The motivation for this problem is to minimize the printing time of…

机器人学 · 计算机科学 2021-03-16 Kedar Karpe , Avinash Sinha , Shreyas Raorane , Ayon Chatterjee , Pranav Srinivas , Lorenzo Sabattini

We investigate coresets - succinct, small summaries of large data sets - so that solutions found on the summary are provably competitive with solution found on the full data set. We provide an overview over the state-of-the-art in coreset…

机器学习 · 统计学 2017-06-06 Olivier Bachem , Mario Lucic , Andreas Krause

As AI models expand in size, it has become increasingly challenging to deploy federated learning (FL) on resource-constrained edge devices. To tackle this issue, split federated learning (SFL) has emerged as an FL framework with reduced…

机器学习 · 计算机科学 2025-04-22 Zheng Lin , Wei Wei , Zhe Chen , Chan-Tong Lam , Xianhao Chen , Yue Gao , Jun Luo

Finding the ground state of Ising spin glasses is notoriously difficult due to disorder and frustration. Often, this challenge is framed as a combinatorial optimization problem, for which a common strategy employs simulated annealing, a…

Clustering is a crucial task in various domains of knowledge, including medicine, epidemiology, genomics, environmental science, economics, and visual sciences, among others. Methodologies for inferring the number of clusters have often…

统计方法学 · 统计学 2025-05-26 Clara Grazian