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We consider likelihood-based two-step estimation of latent variable models, in which just the measurement model is estimated in the first step and the measurement parameters are then fixed at their estimated values in the second step where…

统计方法学 · 统计学 2025-08-26 Jouni Kuha , Zsuzsa Bakk

Motivated by reduction of computational complexity, this work develops sign-error adaptive filtering algorithms for estimating time-varying system parameters. Different from the previous work on sign-error algorithms, the parameters are…

最优化与控制 · 数学 2016-11-17 Araz Hashemi , G. Yin , Le Yi Wang

Interval-censored multi-state data arise in many studies of chronic diseases, where the health status of a subject can be characterized by a finite number of disease states and the transition between any two states is only known to occur…

统计方法学 · 统计学 2022-09-19 Yu Gu , Donglin Zeng , Gerardo Heiss , D. Y. Lin

Markov networks are popular models for discrete multivariate systems where the dependence structure of the variables is specified by an undirected graph. To allow for more expressive dependence structures, several generalizations of Markov…

统计方法学 · 统计学 2021-03-30 Johan Pensar , Henrik Nyman , Jukka Corander

Automata learning techniques automatically generate system models from test observations. These techniques usually fall into two categories: passive and active. Passive learning uses a predetermined data set, e.g., system logs. In contrast,…

机器学习 · 计算机科学 2019-07-01 Martin Tappler , Bernhard K. Aichernig , Giovanni Bacci , Maria Eichlseder , Kim G. Larsen

We study very simple sorting algorithms based on a probabilistic comparator model. In our model, errors in comparing two elements are due to (1) the energy or effort put in the comparison and (2) the difference between the compared…

数据结构与算法 · 计算机科学 2018-05-16 Barbara Geissmann , Paolo Penna

We propose a numerical technique for parameter inference in Markov models of biological processes. Based on time-series data of a process we estimate the kinetic rate constants by maximizing the likelihood of the data. The computation of…

定量方法 · 定量生物学 2011-02-15 Aleksandr Andreychenko , Linar Mikeev , David Spieler , Verena Wolf

Interval-censored multi state data is collected when the state of a subject is observed periodically. The analysis of such data using non-parametric multi-state models was not possible until recently, but is very desirable as it allows for…

统计方法学 · 统计学 2025-07-16 Daniel Gomon , Hein Putter

Multi-state models are commonly used for intermittent observations of a state over time, but these are generally based on the Markov assumption, that transition rates are independent of the time spent in current and previous states. In a…

统计方法学 · 统计学 2026-05-07 Christopher Jackson

We present a probabilistic ranking model to identify the optimal treatment in multiple-response experiments. In contemporary practice, treatments are applied over individuals with the goal of achieving multiple ideal properties on them…

Dynamical models of cognition play an increasingly important role in driving theoretical and experimental research in psychology. Therefore, parameter estimation, model analysis and comparison of dynamical models are of essential…

In this paper we consider a reduced-form intensity-based credit risk model with a hidden Markov state process. A filtering method is proposed for extracting the underlying state given the observation processes. The method may be applied to…

计算金融 · 定量金融 2016-03-10 Feng-Hui Yu , Wai-Ki Ching , Jia-Wen Gu , Tak-Kuen Siu

If the state space of a homogeneous continuous-time Markov chain is too large, making inferences - here limited to determining marginal or limit expectations - becomes computationally infeasible. Fortunately, the state space of such a chain…

概率论 · 数学 2018-06-01 Alexander Erreygers , Jasper De Bock

This paper studies the fundamental problem of learning deep generative models that consist of multiple layers of latent variables organized in top-down architectures. Such models have high expressivity and allow for learning hierarchical…

机器学习 · 统计学 2020-07-21 Erik Nijkamp , Bo Pang , Tian Han , Linqi Zhou , Song-Chun Zhu , Ying Nian Wu

A fundamental question in the field of molecular computation is what computational tasks a biochemical system can carry out. In this work, we focus on the problem of finding the maximum likelihood estimate (MLE) for log-affine models. We…

分子网络 · 定量生物学 2025-10-06 Oskar Henriksson , Carlos Améndola , Jose Israel Rodriguez , Polly Y. Yu

Bandit algorithms are guaranteed to solve diverse sequential decision-making problems, provided that a sufficient exploration budget is available. However, learning from scratch is often too costly for personalization tasks where a single…

机器学习 · 计算机科学 2025-08-08 Newton Mwai , Emil Carlsson , Fredrik D. Johansson

Phenotypic variability in a population of cells can work as the bet-hedging of the cells under an unpredictably changing environment, the typical example of which is the bacterial persistence. To understand the strategy to control such…

种群与进化 · 定量生物学 2019-12-02 So Nakashima , Yuki Sughiyama , Tetsuya J. Kobayashi

Multilevel linear models allow flexible statistical modelling of complex data with different levels of stratification. Identifying the most appropriate model from the large set of possible candidates is a challenging problem. In the…

统计方法学 · 统计学 2022-11-15 Tom Edinburgh , Ari Ercole , Stephen J. Eglen

We consider first the mixed discrete-continuous scheme of observation in multistate models; this is a classical pattern in epidemiology because very often clinical status is assessed at discrete visit times while times of death or other…

统计理论 · 数学 2008-12-18 Daniel Commenges , Anne Gégout-Petit

Forecasting tasks using large datasets gathering thousands of heterogeneous time series is a crucial statistical problem in numerous sectors. The main challenge is to model a rich variety of time series, leverage any available external…

机器学习 · 计算机科学 2024-04-18 Etienne David , Jean Bellot , Sylvain Le Corff
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