相关论文: Operational Design Considerations for Retinal Pros…
Implantable retinal prostheses offer a promising solution to restore partial vision by circumventing damaged photoreceptor cells in the retina and directly stimulating the remaining functional retinal cells. However, the information…
Two computational models to be used as tools for experimental research on the retinal implant are presented. In the first model, the electric field produced by a multi-electrode array in a uniform retina is calculated. In the second model,…
Current steering on a multi-electrode array is commonly used to shape the electric field in the neural tissue in order to improve selectivity and efficacy of stimulation. Previously, simulations of the electric field in tissue required…
Cortical visual prostheses aim to restore sight by electrically stimulating neurons in early visual cortex (V1). With the emergence of high-density and flexible neural interfaces, electrode placement within three-dimensional cortex has…
Clinical trials previously demonstrated the notable capacity to elicit visual percepts in blind patients affected with retinal diseases by electrically stimulating the remaining neurons on the retina. However, these implants restored very…
Retinal implants are a promising treatment option for degenerative retinal disease. While numerous models have been developed to simulate the appearance of elicited visual percepts ("phosphenes"), these models often either focus solely on…
While a great deal is known about the way the retina processes simple stimuli, our understanding of how the retina processes natural stimuli is still limited. Here we highlight some of the challenges that remain to be addressed to…
Retinal implants aim to restore functional vision despite photoreceptor degeneration, yet are fundamentally constrained by low resolution electrode arrays and patient-specific perceptual distortions. Most deployed encoders rely on…
Inner Retinal neurons are a most essential part of the retina and they are supplied with blood via retinal vessels. This paper primarily focuses on the segmentation of retinal vessels using a triple preprocessing approach. DRIVE database…
Corneal inlays (CIs) are the most recent surgical procedure for the treatment of presbyopia in patients who want complete independence from the use of glasses or contact lenses. Although refractive surgery in presbyopic patients is mostly…
Prosthetic vision is being applied to partially recover the retinal stimulation of visually impaired people. However, the phosphenic images produced by the implants have very limited information bandwidth due to the poor resolution and lack…
Retinal degenerative diseases cause profound visual impairment in more than 10 million people worldwide, and retinal prostheses are being developed to restore vision to these individuals. Analogous to cochlear implants, these devices…
Being able to image the human retina in high resolution opens a new era in many important fields, such as pharmacological research for retinal diseases, researches in human cognition, nervous system, metabolism and blood stream, to name a…
Retinal projection is required for xR applications that can deliver immersive visual experience throughout the day. If general-purpose retinal projection methods can be realized at a low cost, not only could the image be displayed on the…
This work presents a bunched of promising technologies to treat blind people: the bionic eyes. The strategy is to combine a retina implant with software capable to interpret the information received. Along this line of thinking, projects…
Two simple mathematical models of electric neuro-stimulation are derived and discussed. It is found that the common injected-charge model is less realistic than a model, in which a latency period, which follows after a short electric pulse,…
Over the past decade, techniques enabling bidirectional modulation of neuronal activity with single cell precision have rapidly advanced in the form of two-photon optogenetic stimulation. Unlike conventional electrophysiological approaches…
Neuroprosthesis, as one type of precision medicine device, is aiming for manipulating neuronal signals of the brain in a closed-loop fashion, together with receiving stimulus from the environment and controlling some part of our brain/body.…
Recent years have seen increased interest to plasmonic enhancement of nonlinear optical effects, yet there remains an uncertainty of what are the limits of this enhancement. We present a simple and physically transparent theory of plasmonic…
Visual prostheses are designed to restore partial functional vision in patients with total vision loss. Retinal visual prostheses provide limited capabilities as a result of low resolution, limited field of view and poor dynamic range.…