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Electrical neural signalling typically takes place at the time-scale of milliseconds, and is typically modeled using the cable equation. This is a good approximation for processes when ionic concentrations vary little during the time course…

细胞行为 · 定量生物学 2014-03-05 Geir Halnes , Ivar Østby , Klas H. Pettersen , Stig W. Omholt , Gaute T. Einevoll

A model for the transmission dynamics of gonorrhoea with control incorporating passive immunity is formulated. We show that introduction of treatment or control parameters leads to transcritical bifurcation. The backward bifurcation…

Computation in the brain involves multiple types of neurons, yet the organizing principles for how these neurons work together remain unclear. Information theory has offered explanations for how different types of neurons can optimize the…

神经元与认知 · 定量生物学 2015-06-22 David B. Kastner , Stephen A. Baccus , Tatyana O. Sharpee

Many phenomena in nature are described by excitable systems driven by colored noise. The temporal correlations in the fluctuations hinder an analytical treatment. We here present a general method of reduction to a white-noise system,…

统计力学 · 物理学 2015-11-25 Jannis Schuecker , Markus Diesmann , Moritz Helias

We study the energy transfer in a classical dipole chain of $N$ interacting rigid rotating dipoles. The underlying high--dimensional potential energy landscape is analyzed in particular by determining the equilibrium points and their…

混沌动力学 · 物理学 2018-08-15 Alexandra Zampetaki , J. Pablo Salas , Peter Schmelcher

The repertoire of neural activity patterns that a cortical network can produce constrains the network's ability to transfer and process information. Here, we measured activity patterns obtained from multi-site local field potential (LFP)…

神经元与认知 · 定量生物学 2010-12-17 Woodrow L. Shew , Hongdian Yang , Shan Yu , Rajarshi Roy , Dietmar Plenz

Creating a quantitative theory for the cortex presents challenges and raises questions. What are the significant scales--micro, meso, or macroscopic? What are the interactions--pairwise, higher order, or mean-field? And what control…

神经元与认知 · 定量生物学 2025-05-29 Nima Dehghani

The theoretical basis of neuronal coding, associated with short term degradation in synaptic transmission, is a matter of debate in the literature. In fact, electrophysiological signals are commonly characterized as inversely proportional…

神经元与认知 · 定量生物学 2017-11-21 A. J. da Silva , S. Floquet , D. O. C. Santos

Functional brain networks can change rapidly as a function of stimuli or cognitive shifts. Tracking dynamic functional connectivity is particularly challenging as it requires estimating the structure of the network at each moment as well as…

统计方法学 · 统计学 2024-04-30 Wan-Chi Hsin , Uri T. Eden , Emily P. Stephen

The time elapsed model describes the firing activity of an homogeneous assembly of neurons thanks to the distribution of times elapsed since the last discharge. It gives a mathematical description of the probability density of neurons…

偏微分方程分析 · 数学 2011-09-16 Khashayar Pakdaman , Benoît Perthame , Delphine Salort

Many mathematical models of interacting agents assume that individual interactions scale down in proportion to the network size, ensuring that the combined input received from the network does not diverge. In theoretical neuroscience,…

偏微分方程分析 · 数学 2025-11-10 Cristobal Quininao , Jonathan Touboul

Currently we routinely develop a complex neuronal network to explain observed but often paradoxical phenomena based upon biological recordings. Here we present a general approach to demonstrate how to mathematically tackle such a complex…

定量方法 · 定量生物学 2015-06-03 Yu Wu , Wenlian Lu , Wei Lin , Gareth Leng , Jianfeng Feng

The steady-state current-voltage response of ion-selective systems varies as the number of ion-selective components is varied. For the highly investigated unipolar system, including only one ion-selective component, it has been shown that…

介观与纳米尺度物理 · 物理学 2024-11-27 Ramadan Abu-Rjal , Yoav Green

Behavioral control over stressful stimuli induces resilience to future conditions when control is lacking. The medial prefrontal cortex(mPFC) is a critically important brain region required for plasticity of stress resilience. We found that…

神经元与认知 · 定量生物学 2012-04-06 Juan A. Varela , Jungang Wang , Andrew L. Varnell , Donald C. Cooper

Network control theory has recently emerged as a promising approach for understanding brain function and dynamics. By operationalizing notions of control theory for brain networks, it offers a fundamental explanation for how brain dynamics…

定量方法 · 定量生物学 2020-03-20 Shikuang Deng , Shi Gu

We investigate the performance of sparsely-connected networks of integrate-and-fire neurons for ultra-short term information processing. We exploit the fact that the population activity of networks with balanced excitation and inhibition…

神经元与认知 · 定量生物学 2007-05-23 Julien Mayor , Wulfram Gerstner

We report a noise induced delay of bifurcation in a simple pulse-coupled neural circuit. We study the behavior of two neural oscillators, each individually governed by saddle-node dynamics, with reciprocal excitatory synaptic connections.…

生物物理 · 物理学 2007-05-23 Boris Gutkin , Tim Hely , Juergen Jost

In neurosciences, the brain processes information via the firing patterns of connected neurons operating across a spectrum of frequencies. To better understand the effects of these frequencies in the neuron dynamics, we have simulated a…

神经元与认知 · 定量生物学 2025-11-21 Gabriel Marghoti , Thiago L. Prado , Miguel A. F. Sanjuán , Sergio R. Lopes

The theory of `Balanced Neural Networks' is a very popular explanation for the high degree of variability and stochasticity in the brain's activity. We determine equations for the hydrodynamic limit of a balanced all-to-all network of 2n…

数学物理 · 物理学 2024-12-24 James MacLaurin , Pedro Vilanova

Brain rhythms contribute to every aspect of brain function. Here, we study critical and resonance phenomena that precede the emergence of brain rhythms. Using an analytical approach and simulations of a cortical circuit model of neural…

无序系统与神经网络 · 物理学 2015-06-12 A. V. Goltsev , M. A. Lopes , K. -E. Lee , J. F. F. Mendes