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Building mathematical models of brains is difficult because of the sheer complexity of the problem. One potential starting point is through basal cognition, which gives abstract representation of a range of organisms without central nervous…

神经元与认知 · 定量生物学 2024-11-08 Linnéa Gyllingberg , Yu Tian , David J. T. Sumpter

We study some mechanisms responsible for synchronous oscillations and loss of synchrony at physiologically relevant frequencies (10-200 Hz) in a network of heterogeneous inhibitory neurons. We focus on the factors that determine the level…

神经元与认知 · 定量生物学 2007-05-23 J. A. White , C. C. Chow , J. Ritt , C. Soto-Trevino , N. Kopell

Biological rhythms are generated by pacemaker organs, such as the heart pacemaker organ (the sinoatrial node) and the master clock of the circadian rhythms (the suprachiasmatic nucleus), which are composed of a network of autonomously…

细胞行为 · 定量生物学 2016-08-23 Hiroshi Kori , Yoji Kawamura , Naoki Masuda

Backpropagation-optimized artificial neural networks, while precise, lack robustness, leading to unforeseen behaviors that affect their safety. Biological neural systems do solve some of these issues already. Unlike artificial models,…

神经与进化计算 · 计算机科学 2025-02-04 Konstantin Holzhausen , Mia Merlid , Håkon Olav Torvik , Anders Malthe-Sørenssen , Mikkel Elle Lepperød

Complex coherent dynamics is present in a wide variety of neural systems. A typical example is the voltage transitions between up and down states observed in cortical areas in the brain. In this work, we study this phenomenon via a…

神经元与认知 · 定量生物学 2015-05-19 Jorge F. Mejias , Hilbert J. Kappen , Joaquin J. Torres

The interplay between activity and elasticity often found in active and living systems triggers a plethora of autonomous behaviors ranging from self-assembly and collective motion to actuation. Amongst these, spontaneous self-oscillations…

软凝聚态物质 · 物理学 2023-04-07 Ellen Zheng , Martin Brandenbourger , Louis Robinet , Peter Schall , Edan Lerner , Corentin Coulais

An electronic circuit device, inspired on the FitzHugh-Nagumo model of neuronal excitability, was constructed and shown to operate with characteristics compatible with those of biological sensory neurons. The nonlinear dynamical model of…

Cell signaling, gene expression, and metabolism are affected by cell-cell heterogeneity and random changes in the environment. The effects of such fluctuations on cell signaling and gene expression have recently been studied intensively…

生物物理 · 物理学 2015-04-02 A. -K. Gustavsson , C. B. Adiels , B. Mehlig , M. Goksör

Since the earliest electroencephalography experiments, large scale oscillations have been observed in the mammalian brain. More recently, episodes of oscillation and bursting have been identified not only in the cerebral cortex and…

神经元与认知 · 定量生物学 2025-09-03 Daniel Pouzzner

The conventional impedance profile of a neuron can identify the presence of resonance and other properties of the neuronal response to oscillatory inputs, such as nonlinear response amplifications, but it cannot distinguish other nonlinear…

We analyze the influence of music in a network of FitzHugh-Nagumo oscillators with empirical structural connectivity measured in healthy human subjects. We report an increase of coherence between the global dynamics in our network and the…

适应与自组织系统 · 物理学 2022-06-10 Jakub Sawicki , Lenz Hartmann , Rolf Bader , Eckehard Schöll

High auditory sensitivity, sharp frequency selectivity, and otoacoustic emissions are signatures of active amplification of the cochlea. The human ear can also detect very large amplitude sound without being damaged as long as the exposed…

生物物理 · 物理学 2008-10-01 Yong Zhang , Chul Koo Kim , Kong-Ju-Bock Lee , Youngah Park

Oscillations are omnipresent in neural population signals, like multi-unit recordings, EEG/MEG, and the local field potential. They have been linked to the population firing rate of neurons, with individual neurons firing in a…

神经元与认知 · 定量生物学 2017-02-08 Hannah Bos , Markus Diesmann , Moritz Helias

Motile cilia are slender, hair-like cellular appendages that spontaneously oscillate under the action of internal molecular motors and are typically found in dense arrays. These active filaments coordinate their beating to generate…

软凝聚态物质 · 物理学 2022-01-28 Brato Chakrabarti , Sebastian Fürthauer , Michael J. Shelley

In the light of recent experimental findings that gap junctions are essential for low level intensity detection in the sensory periphery, the Greenberg-Hastings cellular automaton is employed to model the response of a two-dimensional…

神经元与认知 · 定量生物学 2016-09-08 Mauro Copelli , Osame Kinouchi

The means by which neuronal activity yields robust behavior is a ubiquitous question in neuroscience. In the songbird, the timing of a highly stereotyped song motif is attributed to the cortical nucleus HVC, and to feedback to HVC from…

神经元与认知 · 定量生物学 2018-01-22 Eve Armstrong

Determining how synaptic coupling within and between regions is modulated during sensory processing is an important topic in neuroscience. Electrophysiological recordings provide detailed information about neural spiking but have…

神经元与认知 · 定量生物学 2018-02-07 Andrea K. Barreiro , Shree Hari Gautam , Woodrow L. Shew , Cheng Ly

We propose a general approach to the question of how biological rhythms spontaneously self-regulate, based on the concept of ``stochastic feedback''. We illustrate this approach by considering the neuroautonomic regulation of the heart…

统计力学 · 物理学 2009-10-30 Plamen Ch. Ivanov , Luis A. N. Amaral , Ary Goldberger , H. Eugene Stanley

We report experimental studies of synchronization phenomena in a pair of biological neurons that interact through naturally occurring, electrical coupling. When these neurons generate irregular bursts of spikes, the natural coupling…

We present a model of a coupled system of the olfactory bulb and cortex. Odor inputs to the epithelium are transformed to oscillatory bulbar activities. The cortex recognizes the odor by resonating to the bulbar oscillating pattern when the…

生物物理 · 物理学 2007-05-23 Zhaoping Li , John Hertz