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Microorganisms often perform chemotaxis, (i.e., sensing and moving toward a region with a higher concentration of an attractive chemical) by changing the rate of tumbling for random walk. We studied several models with internal adaptive…

统计力学 · 物理学 2009-11-11 Masayo Inoue , Kunihiko Kaneko

We consider signal transaction in a simple neuronal model featuring intrinsic noise. The presence of noise limits the precision of neural responses and impacts the quality of neural signal transduction. We assess the signal transduction…

生物物理 · 物理学 2015-03-17 Michael J. Barber , Manfred L. Ristig

Cells can utilize chemical communication to exchange information and coordinate their behavior in the presence of noise. Communication can reduce noise to shape a collective response, or amplify noise to generate distinct phenotypic…

分子网络 · 定量生物学 2019-09-24 David T. Gonzales , T-Y Dora Tang , Christoph Zechner

Synchronization is a widespread phenomenon observed in physical, biological, and social networks, which persists even under the influence of strong noise. Previous research on oscillators subject to common noise has shown that noise can…

适应与自组织系统 · 物理学 2021-06-02 Zachary G. Nicolaou , Michael Sebek , Istvan Z. Kiss , Adilson E. Motter

Cells are constantly exposed to fluctuating environmental conditions. External signals are sensed, processed and integrated by cellular signal transduction networks, which translate input signals into specific cellular responses by means of…

分子网络 · 定量生物学 2012-05-29 Pau Rué , Núria Domedel-Puig , Jordi Garcia-Ojalvo , Antonio J. Pons

When cells measure concentrations of chemical signals, they may average multiple measurements over time in order to reduce noise in their measurements. However, when cells are in a environment that changes over time, past measurements may…

细胞行为 · 定量生物学 2025-03-05 Aparajita Kashyap , Wei Wang , Brian A. Camley

Bacterial chemotaxis in Escherichia coli is a canonical system for the study of signal transduction. A remarkable feature of this system is the coexistence of precise adaptation in population with large fluctuating cellular behavior in…

分子网络 · 定量生物学 2019-08-19 Thierry Emonet , Philippe Cluzel

Unraveling bacterial strategies for spatial exploration is crucial for understanding the complexity in the organization of life. Bacterial motility determines the spatio-temporal structure of microbial communities, controls infection…

Neurons in the central nervous system are affected by complex and noisy signals due to fluctuations in their cellular environment and in the inputs they receive from many other cells 1,2. Such noise usually increases the probability that a…

神经元与认知 · 定量生物学 2008-05-06 Boris S. Gutkin , Juergen Jost , Henry C. Tuckwell

Bacterial chemotaxis for E.coli is controlled by methylation of chemoreceptors, which in a biochemical pathway regulates the concentration of the CheY-P protein that finally controls the tumbling rate. As a consequence, the tumbling rate…

软凝聚态物质 · 物理学 2025-04-23 Manuel Mayo , Rodrigo Soto

Hybrid models of chemotaxis combine agent-based models of cells with partial differential equation models of extracellular chemical signals. In this paper, travelling wave properties of hybrid models of bacterial chemotaxis are…

生物物理 · 物理学 2013-02-13 Benjamin Franz , Chuan Xue , Kevin J. Painter , Radek Erban

Adaptation of the chemotaxis sensory pathway of the bacterium Escherichia coli is integral for detecting chemicals over a wide range of background concentrations, ultimately allowing cells to swim towards sources of attractant and away from…

细胞行为 · 定量生物学 2015-05-18 Diana Clausznitzer , Olga Oleksiuk , Linda Lovdok , Victor Sourjik , Robert G. Endres

{\sl Escherichia coli} ({\sl E. coli}) bacteria govern their trajectories by switching between running and tumbling modes as a function of the nutrient concentration they experienced in the past. At short time one observes a drift of the…

统计力学 · 物理学 2011-12-08 Sakuntala Chatterjee , Rava Azeredo da Silveira , Yariv Kafri

Bacterial chemotactic sensing converts noisy chemical signals into running and tumbling. We analyze the static sensing limits of mixed Tar/Tsr chemoreceptor clusters in individual Escherichia coli cells using a heterogeneous…

定量方法 · 定量生物学 2026-02-24 Ziyi Cui , Sarah Marzen

We use particle dynamics simulations to probe the correlations between noise and dynamics in a variety of disordered systems, including superconducting vortices, 2D electron liquid crystals, colloids, domain walls, and granular media. The…

超导电性 · 物理学 2009-11-10 C. J. Olson Reichhardt , C. Reichhardt

Cooperative interactions among the binding of multiple signaling molecules is a common mechanism for enhancing the sensitivity of biological signaling systems. It is widely assumed that this increase in sensitivity of the mean response…

分子网络 · 定量生物学 2007-05-23 William Bialek , Sima Setayeshgar

Stochastic resonance is a non-linear phenomenon, in which the sensitivity of signal detectors can be enhanced by adding random noise to the detector input. Here, we demonstrate that noise can also improve the information flux in recurrent…

神经元与认知 · 定量生物学 2018-11-30 Patrick Krauss , Karin Prebeck , Achim Schilling , Claus Metzner

The movement of single kinesin molecules was observed while applying noisy external forces that mimic intracellular active fluctuations. We found kinesin accelerates under noise, especially when a large hindering load is added. The behavior…

生物物理 · 物理学 2021-11-02 Takayuki Ariga , Keito Tateishi , Michio Tomishige , Daisuke Mizuno

We find that sensory noise delivered together with a weak periodic signal not only enhances nonlinear response of neuronal networks, but also improves the synchronization of the response to the signal. We reveal this phenomenon in neuronal…

神经元与认知 · 定量生物学 2015-08-25 M. A. Lopes , K. -E. Lee , A. V. Goltsev , J. F. F. Mendes

We present the first experimental realization of a ratchet cellular automaton (RCA) which has been recently suggested as an alternative approach for performing logical operations with interacting (quasi) particles. Our study was performed…

软凝聚态物质 · 物理学 2009-11-11 Dusan Babic , Clemens Bechinger