相关论文: Model of cell response to {\alpha}-particle radiat…
Radiation reaction, the force experienced by an accelerated charge due to radiation emission, has long been the subject of extensive theoretical and experimental research. Experimental verification of a quantum, strong-field description of…
We present a theoretical agent-based model of cell evolution under the action of cytotoxic treatments, such as radioteraphy or chemoteraphy. The major features of cell cycle and proliferation, cell damage and repair, and chemical diffusion…
Soon available multi petawatt ultra-high-intensity (UHI) lasers will allow us to probe high-amplitude electromagnetic fields interacting with either ultra-relativistic electron beams or hot plasmas in the so-called moderately quantum…
By representing damage induction by ionizing particles and its repair by the cell, the probabilistic two-stage model provides a detailed description of the main processes involved in cell killing by radiation. To link this model with issues…
The radiation caused by particles of one bunch in the collective electromagnetic field of the short oncoming bunch is studied. Quantum effects are calculated for the spectrum of radiated photons. Using this spectrum, the dependence of the…
Background: Radiotherapy outcomes are usually predicted using the Linear Quadratic model. However, this model does not integrate complex features of tumor growth, in particular cell cycle regulation. Methods: In this paper, we propose a…
FLASH radiation has been reported to efficiently suppress tumor growth while sparing normal tissue, however, the mechanism of the differential tissue sparing effect is still not known. Oxygen has long been known to profoundly impact…
We propose formulas of the nuclear beta-decay rate that are useful in a practical calculation. The decay rate is determined by the product of the lepton and hadron current densities. A widely used formula relies upon the fact that the…
Accurately linking microscopic energy deposition from ionizing radiation to emergent biological outcomes remains a central challenge in radiobiological modelling, particularly when stochastic damage induction, cell-cycle dynamics, and…
Radiation-reaction in the interaction of ultra-relativistic electrons with a strong external electromagnetic field is investigated using a kinetic approach in the weakly quantum regime ($\chi \lesssim 1$, with $\chi$ the electron quantum…
A point charge accelerating under the influence of an external force emits electromagnetic radiation that reduces the increase in its mechanical energy. This causes a reduction in the particle's acceleration. We derive the decrease in…
This work investigates the change in cell survival predicted by the local effect model (LEM) for an irradiated cell containing metal nanoparticles (MNPs) depending on the distribution of neighboring cells and the uptake of MNPs into the…
The effect of the electromagnetic radiation on the spontaneous charge emission from heavy atomic nuclei is estimated in a model which may be relevant for proton emission and alpha-particle decay in laser fields. Arguments are given that the…
Ion-induced cell killing has been reported to depend on the irradiation dose but also on the projectile parameters. In this paper we focus on two approaches developed and extensively used to predict cell survival in response to ion…
Computing reaction rates in biomolecular systems is a common goal of molecular dynamics simulations. The reactions considered often involve conformational changes in the molecule, either changes in the structure of a protein or the relative…
The radiative transfer equation for spectral lines from an extended gas is derived from first principles, treating the gas as a system of many atoms/molecules rather than isolated ones. Line broadening effects are assumed to be dominated by…
We model the emission of high energy photons due to relativistic charged particle motion in intense laser-plasma interactions. This is done within a particle-in-cell code, for which high frequency radiation normally cannot be resolved due…
Many astrophysical sources radiate via synchrotron emission from relativistic electrons. The electrons give off their kinetic energy as radiation and this radiative loss modifies the electron energy distribution. An analytical treatment of…
We derive a simple analytical formula to describe the evolution of spectral index $\beta$ in the steep decay phase shaped by the curvature effect with assumption that the spectral parameters and Lorentz factor of jet shell is the same for…
We developed a mathematical model to simulate the growth of tumor volume and its response to a single fraction of high dose irradiation. We made several key assumptions of the model. Tumor volume is composed of proliferating (or dividing)…