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In-vivo examination of the physical connectivity of axonal projections through the white matter of the human brain is made possible by diffusion weighted magnetic resonance imaging (dMRI) Analysis of dMRI commonly considers derived scalar…

图像与视频处理 · 电气工程与系统科学 2019-12-03 Haraldur T. Hallgrimsson , Richika Sharan , Scott T. Grafton , Ambuj K. Singh

Development of successful therapies for neurological disorders depends on our ability to diagnose and monitor the progression of underlying pathologies at the cellular level. Physics and physiology limit the resolution of human MRI to…

生物物理 · 物理学 2016-09-30 Jelle Veraart , Els Fieremans , Dmitry S. Novikov

Diffusion tensor imaging (DTI) is a prevalent neuroimaging tool in analyzing the anatomical structure. The distinguishing feature of DTI is that the voxel-wise variable is a 3x3 positive definite matrix other than a scalar, describing the…

统计方法学 · 统计学 2021-03-30 Zhou Lan

Diffusion tensor imaging (DTI) provides crucial insights into the microstructure of the human brain, but it can be time-consuming to acquire compared to more readily available T1-weighted (T1w) magnetic resonance imaging (MRI). To address…

计算机视觉与模式识别 · 计算机科学 2025-04-22 Shaorong Zhang , Tamoghna Chattopadhyay , Sophia I. Thomopoulos , Jose-Luis Ambite , Paul M. Thompson , Greg Ver Steeg

Diffusion MRI (dMRI) is an advanced imaging technique characterizing tissue microstructure and white matter structural connectivity of the human brain. The demand for high-quality dMRI data is growing, driven by the need for better…

图像与视频处理 · 电气工程与系统科学 2024-08-26 Xi Zhu , Wei Zhang , Yijie Li , Lauren J. O'Donnell , Fan Zhang

We develop a general analytical and numerical framework for estimating intra- and extra-neurite water fractions and diffusion coefficients, as well as neurite orientational dispersion, in each imaging voxel. By employing a set of rotational…

生物物理 · 物理学 2018-04-10 Dmitry S. Novikov , Jelle Veraart , Ileana O. Jelescu , Els Fieremans

High angular resolution diffusion imaging data is the observed characteristic function for the local diffusion of water molecules in tissue. This data is used to infer structural information in brain imaging. Nonparametric scalar measures…

应用统计 · 统计学 2011-08-17 Sofia C. Olhede , Brandon Whitcher

Digital Retinal Fundus Images helps to detect various ophthalmic diseases by detecting morphological changes in optical cup, optical disc and macula. Present work proposes a method for the authentication of medical images based on Discrete…

计算机视觉与模式识别 · 计算机科学 2012-09-04 Nilanjan Dey , Moumita Pal , Achintya Das

Fiber tractography is an important tool of computational neuroscience that enables reconstructing the spatial connectivity and organization of white matter of the brain. Fiber tractography takes advantage of diffusion Magnetic Resonance…

图像与视频处理 · 电气工程与系统科学 2020-09-08 Tomer Weiss , Sanketh Vedula , Ortal Senouf , Oleg Michailovich , AlexBronstein

Many diffusion MRI researchers, including the Human Connectome Project (HCP), acquire data using multishell (e.g., WU-Minn consortium) and diffusion spectrum imaging (DSI) schemes (e.g., USC-Harvard consortium). However, these data sets are…

神经元与认知 · 定量生物学 2023-07-28 Fang-Cheng Yeh , Timothy D. Verstynen

The hydrocephalus can be either an independent disease or a concomitant symptom of a number of pathologies, therefore representing an urgent issue in the present-day clinical practice. Deep Learning is an evolving technology and the part of…

计算机视觉与模式识别 · 计算机科学 2019-09-27 Alexey Demyanchuk , Ekaterina Pushkina , Nikolay Russkikh , Dmitry Shtokalo , Sergey Mishinov

Diffusion MRI tractography technique enables non-invasive visualization of the white matter pathways in the brain. It plays a crucial role in neuroscience and clinical fields by facilitating the study of brain connectivity and neurological…

计算机视觉与模式识别 · 计算机科学 2025-03-06 Yiqiong Yang , Yitian Yuan , Baoxing Ren , Ye Wu , Yanqiu Feng , Xinyuan Zhang

Magnetic resonance diffusion tensor imaging (DTI) is a critical tool for neural disease diagnosis. However, long scan time greatly hinders the widespread clinical use of DTI. To accelerate image acquisition, a feature-enhanced joint…

图像与视频处理 · 电气工程与系统科学 2024-05-28 Lang Zhang , Jinling He , Dong Liang , Hairong Zheng , Yanjie Zhu

Diffusion Tensor Imaging (DTI) is an effective tool for the analysis of structural brain connectivity in normal development and in a broad range of brain disorders. However efforts to derive inherent characteristics of structural brain…

计算工程、金融与科学 · 计算机科学 2018-02-14 Yu Jin , Joseph F. JaJa , Rong Chen , Edward H. Herskovits

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

图像与视频处理 · 电气工程与系统科学 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang

Each voxel in a diffusion MRI (dMRI) image contains a spherical signal corresponding to the direction and strength of water diffusion in the brain. This paper advances the analysis of such spatio-spherical data by developing convolutional…

图像与视频处理 · 电气工程与系统科学 2024-11-19 Axel Elaldi , Guido Gerig , Neel Dey

Diffusion MRI (dMRI) is the primary imaging modality used to study brain microstructure in vivo. Reliable and computationally efficient parameter inference for common dMRI biophysical models is a challenging inverse problem, due to factors…

图像与视频处理 · 电气工程与系统科学 2025-03-03 William Consagra , Lipeng Ning , Yogesh Rathi

Purpose: Free water elimination diffusion tensor imaging (FWE-DTI) has been widely used to distinguish increases of free water (FW) partial volume effects from tissue's diffusion in healthy ageing and degenerative diseases. Since the…

医学物理 · 物理学 2021-07-20 Marc Golub , Rafael Neto Henriques , Rita G. Nunes

Diffusion-weighted imaging (DWI) is a powerful non-invasive tool which is widely used in clinical routine. Mostly, apparent diffusion coefficient maps are acquired, which cannot be directly related to cellular structure. More recently it…

Biophysical modeling is the mediator of evaluating the cellular structure of biological tissues using diffusion-weighted MRI. It is however the bottleneck of microstructural MRI. Beyond the complexity of diffusion, the current development…

生物物理 · 物理学 2017-12-14 Bibek Dhital , Marco Reisert , Elias Kellner , Valerij G. Kiselev