相关论文: Measuring the viscous and elastic properties of si…
In this paper, we study how cytoskeletal remodeling is correlated to changes in subcellular microrheology. We analyze the changes in the magnitude and directionality of the shear and elastic moduli of bovine aortic endothelial cells (BAECs)…
The mechanical properties of cells play key roles in their physiology, function, physiological and pathological transformations. Micro-elastography has recently emerged as a promising tool to estimate cellular viscoelastic properties within…
Cytoplasmic viscoelasticity is crucial for various intracellular processes. However, the dynamic shear modulus, $G(\omega)$, has been reported to vary considerably, often without consistent patterns or rules, even within the same cell.…
We propose a theoretical model which relies on the generalized Langevin equation and may account for various dynamical features of the thermal motion of organelles, vesicles or macromolecules in viscoelastic media such as polymer networks.…
Elasticity is a fundamental cellular property that is related to the anatomy, functionality and pathological state of cells and tissues. However, current techniques based on cell deformation, atomic force microscopy or Brillouin scattering…
Microrheology is the study of the properties of a complex fluid through the diffusion dynamics of small particles, typically latex beads, moving through that material. Currently, it is the dominant technique in the study of the physical…
The mechanical properties of polymer gels based on cytoskeleton proteins (e.g. actin) have been studied extensively due to their significant role in biological cell motility and in maintaining the cell's structural integrity. Microrheology…
The transfer of mechanical signals through cells is a complex phenomenon. To uncover a new mechanotransduction pathway, we study the frequency-dependent transport of mechanical stimuli by single microtubules and small networks in a…
In this paper we present a theoretical and experimental study aimed at characterizing the hysteretic properties of viscoelastic materials. In the last decades viscoelastic materials have become a reference for new technological…
Minimally invasive experimental methods that can measure local rate dependent mechanical properties are essential in understanding the behaviour of soft and biological materials in a wide range of applications. Needle based measurement…
The local viscoelastic (VE) environment governs the motion of an embedded microsphere and consequently, pertinent dynamical phenomena. However, studying such phenomena with varying VE properties remains challenging for various reasons,…
The normal modes and relaxation rates of weak colloidal gels are investigated in computations employing different models of the hydrodynamic interactions between colloids. The eigenspectrum is computed for freely draining,…
We study the dynamics of rigid spheres embedded in viscoelastic media and address two questions of importance to microrheology. First we calculate the complete response to an external force of a single bead in a homogeneous elastic network…
We present a straightforward method for measuring the fluids' relative viscosity via a simple graphical analysis of the normalised position autocorrelation function of an optically trapped bead, without the need of embarking on laborious…
This is an integrated experimental and theoretical study of the dynamics and rheology of self-crosslinked, slightly charged, temperature responsive soft Poly(N-isopropylacrylamide) (pNIPAM) microgels over a wide range of concentration and…
There are many fields where it is of interest to measure the elastic moduli of tiny fragile fibers, such as filamentous bacteria, actin filaments, DNA, carbon nanotubes, and functional microfibers. The elastic modulus is typically deduced…
Biomembranes consisting of two opposing phospholipid monolayers, which comprise the so-called lipid bilayer, are largely responsible for the dual solid-fluid behavior of individual cells and viruses. Quantifying the mechanical…
The macroscopic mechanical properties of colloidal particle gels strongly depend on the local arrangement of the powder particles. Experiments have shown that more heterogeneous microstructures exhibit up to one order of magnitude higher…
We investigated the viscoelastic response of model interphase chromosomes by tracking the three-dimensional motion of hundreds of dispersed Brownian particles of sizes ranging from the thickness of the chromatin fiber up to slightly above…
Recent works indicate that heterogeneous response and non-Markovianity may yield recognizable hallmarks in the microrheology of semisolid viscoelastic materials. Here we perform numerical simulations using a non-Markovian overdamped…