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We consider the effect of noise in sparse Boolean Networks with redundant functions. We show that they always exhibit a non-zero error level, and the dynamics undergoes a phase transition from non-ergodicity to ergodicity, as a function of…

生物物理 · 物理学 2015-03-13 Tiago P. Peixoto

The dynamical organization in the presence of noise of a Boolean neural network with random connections is analyzed. For low levels of noise, the system reaches a stationary state in which the majority of its elements acquire the same…

无序系统与神经网络 · 物理学 2007-05-23 Cristian Huepe , Maximino Aldana

We analyze transport on a graph with multiple constraints and where the weight of the edges connecting the nodes is a dynamical variable. The network dynamics results from the interplay between a nonlinear function of the flow, dissipation,…

统计力学 · 物理学 2023-11-28 Frederic Folz , Kurt Mehlhorn , Giovanna Morigi

We construct and investigate Boolean networks that follow a given reliable trajectory in state space, which is insensitive to fluctuations in the updating schedule, and which is also robust against noise. Robustness is quantified as the…

生物物理 · 物理学 2010-12-02 Christoph Schmal , Tiago P. Peixoto , Barbara Drossel

Gene regulatory networks can be successfully modeled as Boolean networks. A much discussed hypothesis says that such model networks reproduce empirical findings the best if they are tuned to operate at criticality, i.e. at the borderline…

分子网络 · 定量生物学 2016-10-12 Pablo Villegas , José Ruiz-Franco , Jorge Hidalgo , Miguel A. Muñoz

The generating functional method is employed to investigate the synchronous dynamics of Boolean networks, providing an exact result for the system dynamics via a set of macroscopic order parameters. The topology of the networks studied and…

无序系统与神经网络 · 物理学 2015-05-28 Alexander Mozeika , David Saad

We investigate the evolution of Boolean networks subject to a selective pressure which favors robustness against noise, as a model of evolved genetic regulatory systems. By mapping the evolutionary process into a statistical ensemble and…

无序系统与神经网络 · 物理学 2012-04-11 Tiago P. Peixoto

Random boolean networks are a model of genetic regulatory networks that has proven able to describe experimental data in biology. They not only reproduce important phenomena in cell dynamics, but they are also extremely interesting from a…

Recent progress in experimental techniques has enabled us to quantitatively study stochastic and flexible behavior of biological systems. For example, gene regulatory networks perform stochastic information processing and their…

统计力学 · 物理学 2018-06-21 Shun Otsubo , Takahiro Sagawa

We study classes of dynamical systems that can be obtained by constructing recursive networks with monotone Boolean functions. Stack filters in nonlinear signal processing are special cases of such systems. We show an analytical connection…

无序系统与神经网络 · 物理学 2009-07-28 Matti Nykter , Juha Kesseli , Ilya Shmulevich

Many complex networks are known to exhibit sudden transitions between alternative steady states with contrasting properties. Such a sudden transition demonstrates a network's resilience, which is the ability of a system to persist in the…

适应与自组织系统 · 物理学 2021-02-24 Subhendu Bhandary , Taranjot Kaur , Tanmoy Banerjee , Partha Sharathi Dutta

In this paper we study the phase transitions of different types of Random Boolean networks. These differ in their updating scheme: synchronous, semi-synchronous, or asynchronous, and deterministic or non-deterministic. It has been shown…

适应与自组织系统 · 物理学 2007-05-23 Carlos Gershenson

We propose a stochastic dynamical model of noisy neural networks with complex architectures and discuss activation of neural networks by a stimulus, pacemakers and spontaneous activity. This model has a complex phase diagram with…

无序系统与神经网络 · 物理学 2015-05-13 A. V. Goltsev , F. V. de Abreu , S. N. Dorogovtsev , J. F. F. Mendes

Neural-network models of high-level brain functions such as memory recall and reasoning often rely on the presence of stochasticity. The majority of these models assumes that each neuron in the functional network is equipped with its own…

The study of the interplay between the structure and dynamics of complex multilevel systems is a pressing challenge nowadays. In this paper, we use a semi-annealed approximation to study the stability properties of Random Boolean Networks…

物理与社会 · 物理学 2012-10-31 Emanuele Cozzo , Alex Arenas , Yamir Moreno

Pluripotent embryonic stem cells are of paramount importance for biomedical research thanks to their innate ability for self-renewal and differentiation into all major cell lines. The fateful decision to exit or remain in the pluripotent…

分子网络 · 定量生物学 2018-07-04 Yen Ting Lin , Peter G. Hufton , Esther J. Lee , Davit A. Potoyan

Boolean networks have been proposed as potentially useful models for genetic control. An important aspect of these networks is the stability of their dynamics in response to small perturbations. Previous approaches to stability have assumed…

分子网络 · 定量生物学 2015-05-13 Andrew Pomerance , Edward Ott , Michelle Girvan , Wolfgang Losert

We explore the impact of social noise, characterized by nonconformist behavior, on the phase transition within the framework of the majority rule model. The order-disorder transition can reflect the consensus-polarization state in a social…

物理与社会 · 物理学 2024-11-14 Roni Muslim , Didi Ahmad Mulya , Zulkaida Akbar , Rinto Anugraha NQZ

Deterministic and stochastic Boolean network models are build for the dynamics of negative feedback loops of the p53 pathways. It is shown that the main function of the negative feedback in the p53 pathways is to keep p53 at a low steady…

分子网络 · 定量生物学 2009-04-16 Hao Ge , Min Qian

It is an increasingly important problem to study conditions on the structure of a network that guarantee a given behavior for its underlying dynamical system. In this paper we report that a Boolean network may fall within the chaotic…

分子网络 · 定量生物学 2008-11-04 Winfried Just , German Enciso
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