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We develop, analyse and numerically simulate a model of a prototype, glucose-driven, rhythmic drug delivery device, aimed at hormone therapies, and based on chemomechanical interaction in a polyelectrolyte gel membrane. The pH-driven…

化学物理 · 物理学 2016-04-07 M. Carme Calderer , Yoichiro Mori , Ronald A. Siegel , Lingxing Yao

Local drug delivery has received much recognition in recent years, yet it is still unpredictable how drug efficacy depends on physicochemical properties and delivery kinetics. The purpose of the current study is to provide a useful…

动力系统 · 数学 2016-01-26 Koyel Chakravarty , D C Dalal

Magnetic remote actuation of soft materials is attractive for applications such as transforming materials and medical robots. However, due to manufacturing limitations, microscale magnetoactive devices are scarce -- light-based additive…

软凝聚态物质 · 物理学 2026-05-13 Rachel M. Sun , Andrew Y. Chen , Yiming Ji , Eric M. Stewart , Daryl W. Yee , Carlos M. Portela

Nanocomposites comprised of insulated magnetic single-domain particles are promising candidates for high-frequency, eddy current free, soft magnetic materials, but tend to suffer from low magnetic susceptibility ($<20$). Particle alignment…

Multifunctional nanomaterials combining diagnosis and therapeutic properties have attracted a considerable attention in cancer research. Yet some important challenges are still to be faced, including an optimal coupling between these two…

生物物理 · 物理学 2019-10-31 Yupeng Shi , Flavien Guenneau , Xiaolin Wang , Christophe Hélary , Thibaud Coradin

Nanocarriers are nanosized materials commonly used for targeted-oriented delivery of active compounds, including antimicrobials and small-molecular drugs. They equally represent fundamental and engineering challenges since sophisticated…

软凝聚态物质 · 物理学 2021-01-19 François Sicard , Jhoan Toro-Mendoza

Electroporation is a very useful tool for drug delivery into various diseased tissues of the human body. This technique helps to improve the clinical treatment by transferring drugs into the targeted cells rapidly. In electroporation, drug…

泛函分析 · 数学 2022-08-03 Nilay Mondal , D. C. Dalal

Stimulus-responsive DNA-hydrogels with swelling capabilities are a promising class of materials for biomedical applications such as drug delivery and biosensing. However, translation of these systems to microscale applications requires…

Colorectal cancer (CRC) continues to be a significant global health burden, prompting the need for more effective and targeted therapeutic strategies. Nanoparticle-based drug delivery systems have emerged as a promising approach to address…

其他定量生物学 · 定量生物学 2024-09-10 Mahadi Hasan , Camryn Grace Evett , Jack Burton

Magnetic nanodevices usually include a free layer whose configuration can be changed by spin-polarized current via the spin transfer effect, and a fixed reference layer. Here, we demonstrate that the roles of the free and the reference…

材料科学 · 物理学 2008-10-07 Weng Lee Lim , Andrew Higgins , Sergei Urazhdin

Due to their extraordinary physical and chemical properties carbon nanotubes reveal a promising potential as biomedical agents for heating, temperature sensoring and drug delivery on the cellular level. Filling carbon nanotubes with…

医学物理 · 物理学 2009-07-29 Ruediger Klingeler , Silke Hampel , Bernd Buechner

We investigate diffusion of a peptide drug through Graphene Oxide (GO) membranes that are modeled as a porous layered laminate constructed from aligned flakes of GO. Our experiments using a peptide drug show a tunable non-linear dependence…

材料科学 · 物理学 2015-12-29 T. M. Puvirajesinghe , Z. L. Zhi , R. V. Craster , S. Guenneau

Simple and easy to implement testbeds are needed to further advance molecular communication research. To this end, this paper presents an in-vessel molecular communication testbed using magnetic nanoparticles dispersed in an aqueous…

All-dielectric nanophotonics becomes a versatile tool for various optical applications, including nanothermometry and optical heating. Its general concept includes excitation of Mie resonances in nonplasmonic nanoparticles. However, the…

In this work we investigate the use of nanoporous carrier as drug delivery systems for hydrophobic molecules. By studying a model system made of porous silicon loaded with beta-carotene, we unveil a fundamental limitation of these carriers…

软凝聚态物质 · 物理学 2020-01-23 Chiara Piotto , Paolo Bettotti

Assemblies of magnetic nanoparticles show a great potential for application in biomedicine, in particular, in magnetic hyperthermia. However, to achieve desired therapeutic effect in magnetic hyperthermia the assembly of nanoparticles…

介观与纳米尺度物理 · 物理学 2019-02-07 N. A. Usov

Ferrofluids are typically suspensions of magnetite nanoparticles, and behave as a homogeneous continuum. The production of nanoparticles with a narrow size distribution and the achievement of colloidal stability are important technological…

流体动力学 · 物理学 2017-04-04 S. Afkhami , Y. Renardy

Solid-state nanopores offer a powerful platform for nanoscale analysis of individual analytes, including biomolecules and functionalized nanoparticles, by confining them within a precisely defined sensing region. However, their inherently…

Three-dimensional magnetic nanostructures are an emerging platform capable of creating complex topological magnetic fields. The control of localized nanoscale magnetic fields is seen to be of importance for diverse areas from…

介观与纳米尺度物理 · 物理学 2024-10-31 John Fullerton , Charudatta Phatak

The development of new superconducting ceramic materials, which maintain the superconductivity at very intense magnetic fields, has prompted the development of a new generation of highly homogeneous high field magnets that has trespassed…