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Large-scale neuroscience is generating rich datasets across animals, brain areas and behavioral contexts, yet our modeling efforts remains fragmented across isolated experiments. We argue that understanding behavior requires integrative…

Whether, when, and how causal interactions between neurons can be meaningfully studied from observations of neural activity alone are vital questions in neural data analysis. Here we aim to better outline the concept of functional…

神经元与认知 · 定量生物学 2023-12-05 Ian H. Stevenson

Many empirical studies estimate causal effects in environments where economic units interact through spatial or network connections. In such settings, outcomes are jointly determined, and treatment induced shocks propagate across…

综合经济学 · 经济学 2026-01-05 Mariluz Mate

In recent years, neuroscience has made significant progress in building large-scale artificial neural network (ANN) models of brain activity and behavior. However, there is no consensus on the most efficient ways to collect data and design…

Understanding causal mechanisms across different populations is essential for designing effective public health interventions. Recently, difference graphs have been introduced as a tool to visually represent causal variations between two…

人工智能 · 计算机科学 2025-02-18 Charles K. Assaad

Understanding the relationship between brain activity and behavior is a central goal of neuroscience. Despite significant advances, a fundamental dichotomy persists: neural activity manifests as both discrete spikes of individual neurons…

神经元与认知 · 定量生物学 2025-11-11 Kasra Jalaldoust , Erfan Zabeh

Decisions by humans depend on their estimations given some uncertain sensory data. These decisions can also be influenced by the behavior of others. Here we present a mathematical model to quantify this influence, inviting a further study…

物理与社会 · 物理学 2012-09-25 Gabriel Madirolas , Alfonso Perez-Escudero , Gonzalo G. de Polavieja

Recent advances in neurosciences and psychology have provided evidence that affective phenomena pervade intelligence at many levels, being inseparable from the cognitionaction loop. Perception, attention, memory, learning, decisionmaking,…

人工智能 · 计算机科学 2008-09-30 Luis Paulo Reis , Daria Barteneva , Nuno Lau

This paper discusses the fundamental principles of causal inference - the area of statistics that estimates the effect of specific occurrences, treatments, interventions, and exposures on a given outcome from experimental and observational…

统计方法学 · 统计学 2021-12-03 Francesca Dominici , Falco J. Bargagli-Stoffi , Fabrizia Mealli

Learning causal relationships from empirical observations is a central task in scientific research. A common method is to employ structural causal models that postulate noisy functional relations among a set of interacting variables. To…

机器学习 · 统计学 2023-09-11 Grigor Keropyan , David Strieder , Mathias Drton

The relationship between brain structure and function has been probed using a variety of approaches, but how the underlying structural connectivity of the human brain drives behavior is far from understood. To investigate the effect of…

神经元与认知 · 定量生物学 2018-11-15 Kanika Bansal , John D. Medaglia , Danielle S. Bassett , Jean M. Vettel , Sarah F. Muldoon

Understanding how decision making changes across the lifespan is a central challenge for neuroscience, yet research on cognitive aging has remained largely disconnected from the theoretical and computational advances that now shape modern…

神经元与认知 · 定量生物学 2026-03-04 Michael B. Ryan , Letizia Ye , Anne K. Churchland

Model explanations based on pure observational data cannot compute the effects of features reliably, due to their inability to estimate how each factor alteration could affect the rest. We argue that explanations should be based on the…

机器学习 · 统计学 2019-09-20 Álvaro Parafita , Jordi Vitrià

Experimental results in recent years have shown that adult neurogenesis is a significant phenomenon in the mammalian brain. Little is known, however, about the functional role played by the generation and destruction of neurons in the…

神经元与认知 · 定量生物学 2009-11-10 Guillermo A. Cecchi , Marcelo O. Magnasco

Learning about the causal structure of the world is a fundamental problem for human cognition. Causal models and especially causal learning have proved to be difficult for large pretrained models using standard techniques of deep learning.…

人工智能 · 计算机科学 2026-04-16 Eunice Yiu , Kelsey Allen , Shiry Ginosar , Alison Gopnik

Higher educational institutions constantly look for ways to meet students' needs and support them through graduation. Recent work in the field of learning analytics have developed methods for grade prediction and course recommendations.…

应用统计 · 统计学 2019-06-12 Prableen Kaur , Agoritsa Polyzou , George Karypis

Most models of neurons incorporate a capacitor to account for the marked capacitive behavior exhibited by the cell membrane. However, such capacitance is widely considered constant, thereby neglecting the possible effects of time-dependent…

神经元与认知 · 定量生物学 2025-12-29 Matías Courdurier , Leonel E. Medina , Esteban Paduro

A treatment policy defines when and what treatments are applied to affect some outcome of interest. Data-driven decision-making requires the ability to predict what happens if a policy is changed. Existing methods that predict how the…

机器学习 · 计算机科学 2023-06-21 Çağlar Hızlı , ST John , Anne Juuti , Tuure Saarinen , Kirsi Pietiläinen , Pekka Marttinen

The credibility revolution advances the use of research designs that permit identification and estimation of causal effects. However, understanding which mechanisms produce measured causal effects remains a challenge. The dominant current…

计量经济学 · 经济学 2026-04-08 Jiawei Fu , Tara Slough

Causal Bayesian networks are 'causal' models since they make predictions about interventional distributions. To connect such causal model predictions to real-world outcomes, we must determine which actions in the world correspond to which…

机器学习 · 统计学 2025-02-04 Frederik Hytting Jørgensen , Luigi Gresele , Sebastian Weichwald