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Structural causal models postulate noisy functional relations among a set of interacting variables. The causal structure underlying each such model is naturally represented by a directed graph whose edges indicate for each variable which…

统计理论 · 数学 2022-03-15 David Strieder , Tobias Freidling , Stefan Haffner , Mathias Drton

It is currently accepted that cortical maps are dynamic constructions that are altered in response to external input. Experience-dependent structural changes in cortical microcurcuts lead to changes of activity, i.e. to changes in…

神经元与认知 · 定量生物学 2013-02-26 F. Gafarov , N. Khusnutdinov , F. Galimyanov

Evaluating the causal effect of an intervention on multivariate outcomes is challenging when the outcomes are interdependent and derived rather than directly observed. Effective connectivity, which summarizes the directional neural…

统计方法学 · 统计学 2026-04-02 Haiyue Song , Ani Eloyan , Youjin Lee

The specific connectivity of a neuronal network is reflected in the dynamics of the signals recorded on its nodes. The analysis of how the activity in one node predicts the behaviour of another gives the directionality in their…

定量方法 · 定量生物学 2019-11-21 Víctor J. López-Madrona , Fernanda Matias , Claudio Mirasso , Santiago Canals , Ernesto Pereda

Causal inference, estimating causal effects from observational data, is a fundamental tool in many disciplines. Of particular importance across a variety of domains is the continuous treatment setting, where the variable of intervention has…

机器学习 · 计算机科学 2026-05-15 Christopher Stith , Medha Barath , Vahid Balazadeh , Jesse C. Cresswell , Rahul G. Krishnan

In many scenarios, human decisions are explained based on some high-level concepts. In this work, we take a step in the interpretability of neural networks by examining their internal representation or neuron's activations against concepts.…

机器学习 · 计算机科学 2021-11-09 Mohammad Nokhbeh Zaeem , Majid Komeili

Over the past two decades, considerable strides have been made in advancing neuroscientific techniques, yet challenges remain in attributing causality to observed associations. This review addresses a fundamental issue in observational…

其他定量生物学 · 定量生物学 2025-11-04 Eric W. Bridgeford , Brian S. Caffo , Maya B. Mathur , Russell A. Poldrack

A key question in many network studies is whether the observed correlations between units are primarily due to contagion or latent confounding. Here, we study this question using a segregated graph (Shpitser, 2015) representation of these…

机器学习 · 计算机科学 2025-03-07 Yufeng Wu , Rohit Bhattacharya

Humans and animals exhibit a range of interesting behaviors in dynamic environments, and it is unclear how our brains actively reformat this dense sensory information to enable these behaviors. Experimental neuroscience is undergoing a…

神经元与认知 · 定量生物学 2023-11-07 Aran Nayebi

Many classical models of collective behavior assume that emergent dynamics result from external and observable interactions among individuals. However, how collective dynamics in human populations depend on the internal psychological…

物理与社会 · 物理学 2024-09-27 Alice C Schwarze , Mari Kawakatsu , Sarah Iams , Nina H Fefferman , Tahra L Eissa

Optogenetics is a powerful neuroscience technique for studying how neural circuit manipulation affects behavior. Standard analysis conventions discard information and severely limit the scope of the causal questions that can be probed. To…

统计方法学 · 统计学 2025-07-02 Gabriel Loewinger , Alexander W. Levis , Francisco Pereira

Recent work has shown promising results in causal discovery by leveraging interventional data with gradient-based methods, even when the intervened variables are unknown. However, previous work assumes that the correspondence between…

机器学习 · 计算机科学 2022-07-12 Gonçalo R. A. Faria , André F. T. Martins , Mário A. T. Figueiredo

Causal models bring many benefits to decision-making systems (or agents) by making them interpretable, sample-efficient, and robust to changes in the input distribution. However, spurious correlations can lead to wrong causal models and…

机器学习 · 计算机科学 2020-12-09 Sergei Volodin , Nevan Wichers , Jeremy Nixon

We consider the problem of causal discovery (structure learning) from heterogeneous observational data. Most existing methods assume a homogeneous sampling scheme, which leads to misleading conclusions when violated in many applications. To…

统计方法学 · 统计学 2022-02-01 Fangting Zhou , Kejun He , Yang Ni

Bayesian Networks may be appealing for clinical decision-making due to their inclusion of causal knowledge, but their practical adoption remains limited as a result of their inability to deal with unstructured data. While neural networks do…

机器学习 · 计算机科学 2022-11-16 Paloma Rabaey , Cedric De Boom , Thomas Demeester

A predictive model makes outcome predictions based on some given features, i.e., it estimates the conditional probability of the outcome given a feature vector. In general, a predictive model cannot estimate the causal effect of a feature…

机器学习 · 计算机科学 2023-04-11 Jiuyong Li , Lin Liu , Ziqi Xu , Ha Xuan Tran , Thuc Duy Le , Jixue Liu

Observational studies are a key resource for causal inference but are often affected by systematic biases. Prior work has focused mainly on detecting these biases, via sensitivity analyses and comparisons with randomized controlled trials,…

统计方法学 · 统计学 2025-06-03 Ilker Demirel , Zeshan Hussain , Piersilvio De Bartolomeis , David Sontag

Predictions about people, such as their expected educational achievement or their credit risk, can be performative and shape the outcome that they aim to predict. Understanding the causal effect of these predictions on the eventual outcomes…

机器学习 · 统计学 2022-10-19 Celestine Mendler-Dünner , Frances Ding , Yixin Wang

In this survey we discuss the recent causal panel data literature. This recent literature has focused on credibly estimating causal effects of binary interventions in settings with longitudinal data, emphasizing practical advice for…

计量经济学 · 经济学 2024-06-26 Dmitry Arkhangelsky , Guido Imbens

Causal inference is a science with multi-disciplinary evolution and applications. On the one hand, it measures effects of treatments in observational data based on experimental designs and rigorous statistical inference to draw causal…

统计方法学 · 统计学 2022-09-05 Jingying Zeng , Run Wang