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Few studies that examine the neurogenesis--behaviour relationship formally establish covariation between neurogenesis and behaviour or rule out competing explanations. The behavioural relevance of neurogenesis might therefore be…

神经元与认知 · 定量生物学 2015-06-19 Stanley E. Lazic , Johannes Fuss , Peter Gass

Connecting neural activity to function is a common aim in neuroscience. How to define and conceptualize function, however, can vary. Here I focus on grounding this goal in the specific question of how a given change in behavior is produced…

神经元与认知 · 定量生物学 2023-11-14 Grace W. Lindsay

Classical causal and statistical inference methods typically assume the observed data consists of independent realizations. However, in many applications this assumption is inappropriate due to a network of dependences between units in the…

机器学习 · 计算机科学 2019-07-02 Rohit Bhattacharya , Daniel Malinsky , Ilya Shpitser

Our understanding of neural computation is founded on the assumption that neurons fire in response to a linear summation of inputs. Yet experiments demonstrate that some neurons are capable of complex functions that require interactions…

生物物理 · 物理学 2026-03-23 Christopher W. Lynn

Interpreting the inner function of neural networks is crucial for the trustworthy development and deployment of these black-box models. Prior interpretability methods focus on correlation-based measures to attribute model decisions to…

机器学习 · 计算机科学 2023-06-21 Ola Ahmad , Nicolas Bereux , Loïc Baret , Vahid Hashemi , Freddy Lecue

Many systems neuroscientists want to understand neurons in terms of mediation; we want to understand how neurons are involved in the causal chain from stimulus to behavior. Unfortunately, most tools are inappropriate for that while our…

神经元与认知 · 定量生物学 2020-09-04 Ilenna Simone Jones , Konrad Paul Kording

What is the difference of a prediction that is made with a causal model and a non-causal model? Suppose we intervene on the predictor variables or change the whole environment. The predictions from a causal model will in general work as…

统计方法学 · 统计学 2024-04-27 Jonas Peters , Peter Bühlmann , Nicolai Meinshausen

Research in Cognitive Science suggests that humans understand and represent knowledge of the world through causal relationships. In addition to observations, they can rely on experimenting and counterfactual reasoning -- i.e. referring to…

人工智能 · 计算机科学 2021-05-24 Kanvaly Fadiga , Etienne Houzé , Ada Diaconescu , Jean-Louis Dessalles

A probabilistic model describes a system in its observational state. In many situations, however, we are interested in the system's response under interventions. The class of structural causal models provides a language that allows us to…

统计方法学 · 统计学 2020-01-20 Jonas Peters , Stefan Bauer , Niklas Pfister

Causal inference is central to many areas of artificial intelligence, including complex reasoning, planning, knowledge-base construction, robotics, explanation, and fairness. An active community of researchers develops and enhances…

人工智能 · 计算机科学 2019-11-05 Amanda Gentzel , Dan Garant , David Jensen

The brain did not develop a dedicated device for reasoning. This fact bears dramatic consequences. While for perceptuo-motor functions neural activity is shaped by the input's statistical properties, and processing is carried out at high…

神经元与认知 · 定量生物学 2015-04-21 David Papo

While probabilistic models describe the dependence structure between observed variables, causal models go one step further: they predict, for example, how cognitive functions are affected by external interventions that perturb neuronal…

神经元与认知 · 定量生物学 2021-04-12 Sebastian Weichwald , Jonas Peters

Most traditional models of uncertainty have focused on the associational relationship among variables as captured by conditional dependence. In order to successfully manage intelligent systems for decision making, however, we must be able…

人工智能 · 计算机科学 2015-05-19 David Heckerman , Ross D. Shachter

Adult neurogenesis has long been documented in the vertebrate brain, and recently even in humans. Although it has been conjectured for many years that its functional role is related to the renewing of memories, no clear mechanism as to how…

无序系统与神经网络 · 物理学 2007-05-23 Guillermo A. Cecchi , Leopoldo T. Petreanu , Arturo Alvarez-Buylla , Marcelo O. Magnasco

The field of hypothesis generation promises to reduce costs in neuroscience by narrowing the range of interventional studies needed to study various phenomena. Existing machine learning methods can generate scientific hypotheses from…

机器学习 · 计算机科学 2025-07-04 Zachary C. Brown , David Carlson

Machine learning is the science of discovering statistical dependencies in data, and the use of those dependencies to perform predictions. During the last decade, machine learning has made spectacular progress, surpassing human performance…

机器学习 · 统计学 2016-07-13 David Lopez-Paz

Convenient access to observational data enables us to learn causal effects without randomized experiments. This research direction draws increasing attention in research areas such as economics, healthcare, and education. For example, we…

社会与信息网络 · 计算机科学 2019-12-03 Ruocheng Guo , Jundong Li , Huan Liu

Discovering causal relationships is a hard task, often hindered by the need for intervention, and often requiring large amounts of data to resolve statistical uncertainty. However, humans quickly arrive at useful causal relationships. One…

机器学习 · 统计学 2011-12-01 Pedro A. Ortega

Neural activity fluctuates over a wide range of timescales within and across brain areas. Experimental observations suggest that diverse neural timescales reflect information in dynamic environments. However, how timescales are defined and…

神经元与认知 · 定量生物学 2026-01-21 Roxana Zeraati , Anna Levina , Jakob H. Macke , Richard Gao

Heckerman (1993) defined causal independence in terms of a set of temporal conditional independence statements. These statements formalized certain types of causal interaction where (1) the effect is independent of the order that causes are…

人工智能 · 计算机科学 2015-05-19 David Heckerman , John S. Breese
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