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Molecular motors are single macromolecules that generate forces at the piconewton range and nanometer scale. They convert chemical energy into mechanical work by moving along filamentous structures. In this paper, we study the velocity of…

生物物理 · 物理学 2011-05-06 Yunxin Zhang

A hopping model for molecular motors is presented consisting of a state with asymmetric hopping rates with period 2 and a state with uniform hopping rates. State changes lead to a stationary unidirectional current of a particle. The current…

统计力学 · 物理学 2015-06-25 H. Ambaye , K. W. Kehr

In living cells, molecular motors convert chemical energy into mechanical work. Its thermodynamic energy efficiency, i.e. the ratio of output mechanical work to input chemical energy, is usually high. However, using two-state models, we…

生物物理 · 物理学 2015-03-06 Yunxin Zhang

We propose a two-dimensional model for a complete description of the dynamics of molecular motors, including both the processive movement along track filaments and the dissociation from the filaments. The theoretical results on the…

生物大分子 · 定量生物学 2009-11-10 Ping Xie , Shuo-Xing Dou , Peng-Ye Wang

We discuss the force-velocity relations obtained in a two-state crossbridge model for molecular motors. They can be calculated analytically in two limiting cases: for a large number and for one pair of motors. The effect of the…

软凝聚态物质 · 物理学 2008-02-03 Andrej Vilfan , Erwin Frey , Franz Schwabl

Molecular motors convert chemical energy derived from the hydrolysis of ATP into mechanical energy. A well-studied model of a molecular motor is the flashing ratchet model. We show that this model exhibits a fluctuation relation known as…

统计力学 · 物理学 2015-05-13 D. Lacoste , K. Mallick

Biological functions in each animal cell depend on coordinated operations of a wide variety of molecular motors. Some of the these motors transport cargo to their respective destinations whereas some others are mobile workshops which…

生物物理 · 物理学 2008-03-07 Debashish Chowdhury

Biological molecular motors are high-performance nanomachines that convert chemical energy into mechanical motion via chemomechanical coupling. Their reaction cycles typically comprise a series of intermediate chemical states between the…

生物物理 · 物理学 2025-05-26 Akihiro Fukuda , Yohei Nakayama , Shoichi Toyabe

Dynamic properties of molecular motors whose motion is powered by interactions with specific lattice bonds are studied theoretically with the help of discrete-state stochastic "burnt-bridge" models. Molecular motors are depicted as random…

统计力学 · 物理学 2009-11-24 Maxim N. Artyomov , Alexander Yu. Morozov , Anatoly B. Kolomeisky

A simple model of the two-state ratchet type is proposed for molecular chemical engines that convert chemical free energy into mechanical work and vice versa. The engine works by catalyzing a chemical reaction and turning a rotor.…

统计力学 · 物理学 2018-05-22 Kazuo Sasaki , Ryo Kanada , Satoshi Amari

One-dimensional hopping model is useful to describe the motion of microscopic particle in thermal noise environment, such as motor proteins. Recent experiments about the new generation of light-driven rotary molecular motors found that, the…

化学物理 · 物理学 2010-07-06 Yunxin Zhang

The stochastic driving force exerted by a single molecular motor (e.g., a kinesin, or myosin) moving on a periodic molecular track (microtubule, actin filament, etc.) is discussed from a general viewpoint open to experimental test. An…

统计力学 · 物理学 2009-10-31 Michael E. Fisher , Anatoly B. Kolomeisky

We review the properties of biological motor proteins which move along linear filaments that are polar and periodic. The physics of the operation of such motors can be described by simple stochastic models which are coupled to a chemical…

生物物理 · 物理学 2009-10-31 Frank Julicher

Molecular motors convert chemical energy into mechanical work while operating in an environment dominated by Brownian motion. The aim of this paper is to explore the flow of energy between the molecular motors and its surroundings, in…

统计力学 · 物理学 2011-05-06 Yunxin Zhang

A molecular motor is made of either a single macromolecule or a macromolecular complex. Just like their macroscopic counterparts, molecular motors "transduce" input energy into mechanical work. All the nano-motors considered here operate…

生物物理 · 物理学 2013-07-18 Debashish Chowdhury

We examine the dependence of the physical quantities of the rotatory molecular motor, such as the rotation velocity and the proton translocation rate, on the chemical reaction rate using the model based only on diffusion process. A peculiar…

生物物理 · 物理学 2009-11-10 Hiroshi Miki , Masatoshi Sato , Mahito Kohmoto

The dynamics of active matter driven by interacting molecular motors has a non-potential structure at the local scale. However, we show that there exists a quasi-potential effectively describing the collective self-organization of the…

生物物理 · 物理学 2022-06-15 Haythem Chelly , Pierre Recho

Properties of transport of molecular motors are investigated. A simplified model based on the concept of Brownian ratchets is applied. We analyze a stochastic equation of motion by means of numerical methods. The transport is systematically…

统计力学 · 物理学 2011-12-07 Lukasz Machura , Marcin Kostur , Jerzy Luczka

Dynamics of molecular motors that move along linear lattices and interact with them via reversible destruction of specific lattice bonds is investigated theoretically by analyzing exactly solvable discrete-state ``burnt-bridge'' models.…

软凝聚态物质 · 物理学 2009-11-13 Max N. Artyomov , Alexander Yu. Morozov , Anatoly B. Kolomeisky

Molecular motors perform active movements along cytoskeletal filaments and drive the traffic of organelles and other cargo particles in cells. In contrast to the macroscopic traffic of cars, however, the traffic of molecular motors is…

统计力学 · 物理学 2009-12-04 Stefan Klumpp , Melanie J. I. Müller , Reinhard Lipowsky
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