相关论文: Learning networks from high dimensional binary dat…

Motivated by the challenges in analyzing gut microbiome and metagenomic data, this work aims to tackle the issue of measurement errors in high-dimensional regression models that involve compositional covariates. This paper marks a…

Development of comprehensive prediction models are often of great interest in many disciplines of science, but datasets with information on all desired features often have small sample sizes. We describe a transfer learning approach for…

There has been a lot of work fitting Ising models to multivariate binary data in order to understand the conditional dependency relationships between the variables. However, additional covariates are frequently recorded together with the…

The application of data mining, machine learning and artificial intelligence techniques in the field of diagnostics is not a new concept, and these techniques have been very successfully applied in a variety of applications, especially in…

We devise a machine learning technique to solve the general problem of inferring network links that have time-delays. The goal is to do this purely from time-series data of the network nodal states. This task has applications in fields…

Gene regulatory networks play a crucial role in controlling an organism's biological processes, which is why there is significant interest in developing computational methods that are able to extract their structure from high-throughput…

Deep neural networks tend to make overconfident predictions and often require additional detectors for misclassifications, particularly for safety-critical applications. Existing detection methods usually only focus on adversarial attacks…

Over the past decade network theory has been applied successfully to the study of a variety of complex adaptive systems. However, the application of these techniques to non-human social networks has several shortfalls. Firstly, in most…

Differences between biological networks corresponding to disease conditions can help delineate the underlying disease mechanisms. Existing methods for differential network analysis do not account for dependence of networks on covariates. As…

We consider the task of detecting regulatory elements in the human genome directly from raw DNA. Past work has focused on small snippets of DNA, making it difficult to model long-distance dependencies that arise from DNA's 3-dimensional…

Translating the vast data generated by genomic platforms into reliable predictions of clinical outcomes remains a critical challenge in realizing the promise of genomic medicine largely due to small number of independent samples. In this…

Disordered networks of fragile elastic elements have been proposed as a model for inner porous regions of large bones [Gunaratne et.al., cond-mat/0009221]. In numerical studies, weakening of such networks is seen to be accompanied by…

Retrieving gene functional networks from knowledge databases presents a challenge due to the mismatch between disease networks and subtype-specific variations. Current solutions, including statistical and deep learning methods, often fail…

In this paper, we study the problem of testing the mean vectors of high dimensional data in both one-sample and two-sample cases. The proposed testing procedures employ maximum-type statistics and the parametric bootstrap techniques to…

We propose a new methodology for selecting and ranking covariates associated with a variable of interest in a context of high-dimensional data under dependence but few observations. The methodology successively intertwines the clustering of…

The damage detection problem becomes a more difficult task when the intrinsically nonlinear behavior of the structures and the natural data variation are considered in the analysis because both phenomena can be confused with damage if…

A semi-parametric, non-linear regression model in the presence of latent variables is applied towards learning network graph structure. These latent variables can correspond to unmodeled phenomena or unmeasured agents in a complex system of…

Collection of genotype data in case-control genetic association studies may often be incomplete for reasons related to genes themselves. This non-ignorable missingness structure, if not appropriately accounted for, can result in…

This paper is motivated by the comparison of genetic networks based on microarray samples. The aim is to test whether the differences observed between two inferred Gaussian graphical models come from real differences or arise from…

Anomaly detection is a relevant problem in the area of data analysis. In networked systems, where individual entities interact in pairs, anomalies are observed when pattern of interactions deviates from patterns considered regular. Properly…