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Stent intervention is a recommended therapy to reduce the pressure gradient and restore blood flow for patients with coarctation of the aorta (CoA). In this work, we developed a framework for personalized stent intervention in CoA using in…

医学物理 · 物理学 2022-10-12 Dandan Ma , Yong Wang , Mueed Azhar , Ansgar Adler , Michael Steinmetz , Martin Uecker

Stent implantation in coronary bifurcations presents unique challenges and currently there is no universally accepted stent deployment approach. Despite clinical and computational studies, to date, the effect of each stent implantation…

Spatial patterns of elevated wall shear stress and pressure due to blood flow past aortic stenosis (AS) are studied using GPU-accelerated patient-specific computational fluid dynamics. Three cases of moderate AS, one with a dilated…

流体动力学 · 物理学 2022-12-13 Hadi Zolfaghari , Mervyn Andiapen , Andreas Baumbach , Anthony Mathur , Rich R. Kerswell

The dynamics of a quasi two-dimensional isotropic droplet in a cholesteric liquid crystal medium under symmetric shear flow is studied by lattice Boltzmann simulations. We consider a geometry in which the flow direction is along the axis of…

软凝聚态物质 · 物理学 2018-07-13 Federico Fadda , Giuseppe Gonnella , Antonio Lamura , Enzo Orlandini , Adriano Tiribocchi

Flow diversion has become a key treatment modality for selected intracranial aneurysms, relying on the principle that a dense mesh of stent wires disrupts blood flow into the aneurysm sac, promoting thrombosis and vessel reconstruction.…

A canonical problem of axially strained flow in a duct of circular-sector cross-section, with fluid injection through the circular arc, is examined for a range of Reynolds numbers and sector angles. At small Reynolds numbers, the flow…

流体动力学 · 物理学 2025-08-19 Prabakaran Rajamanickam

With an aim to investigate the effect of externally imposed body acceleration and magnetic field on pulsatile flow of blood through an arterial segment having stenosis is under consideration in this paper. The flow of blood is presented by…

数值分析 · 数学 2012-09-25 G. C. Shit , M. Roy

In this article, effects of heat transfer on MHD blood flow through a stenosed inclined porous artery with heat source have been investigated. The viscosity of the blood is assumed to be varying radially with hematocrit throughout the…

流体动力学 · 物理学 2018-05-31 Bhavya Tripathi , Bhupendra Kumar Sharma

Immersed nonlinear elements are prevalent in biological systems that require a preferential flow direction, such as the venous and the lymphatic system. We investigate here a certain class of models where the fluid is driven by peristaltic…

流体动力学 · 物理学 2024-11-20 Aaron Winn , Eleni Katifori

Cardiovascular diseases are a leading cause of death globally. Among them, some are linked to stenosis, which is an abnormal narrowing of blood vessels, as well as other factors. Smart drug delivery systems based on micro- and nanoparticles…

流体动力学 · 物理学 2025-11-18 R. Dapena-García , V. Pérez-Muñuzuri

A finite element analysis of flows of an Oldroyd-B fluid is developed, to simulate blood flow in an arteriovenous fistula. The model uses a combination of a standard conforming finite element approximation for the momentum equation, and the…

医学物理 · 物理学 2020-03-19 Nkosilathi Vundla , B. Daya Reddy

We report computational results of blood flow through a model of the human aortic arch and a vessel of actual diameter and length. On the top of the aortic arch the branching of the %%three arteries are included: the subclavian and jugular.…

流体动力学 · 物理学 2008-11-11 Renat A. Sultanov , Dennis Guster

The separating and reattaching turbulent flow past a rectangular cylinder is studied to describe how small and large scales contribute to the sustaining mechanism of the velocity fluctuations. The work is based on the Anisotropic…

流体动力学 · 物理学 2022-08-24 Alessandro Chiarini , Davide Gatti , Andrea Cimarelli , Maurizio Quadrio

Microfluidic systems are usually fabricated with soft materials that deform due to the fluid stresses. Recent experimental and theoretical studies on the steady flow in shallow deformable microchannels have shown that the flow rate is a…

流体动力学 · 物理学 2020-09-14 A. Martínez-Calvo , A. Sevilla , G. G. Peng , H. A. Stone

We study the impact of using fluid-structure interactions (FSI) to simulate blood flow in a large stenosed artery. We compare typical flow configurations using Navier-Stokes in a rigid geometry setting to a fully coupled FSI model. The…

计算物理 · 物理学 2021-02-01 Lukas Failer , Piotr Minakowski , Thomas Richter

Strokes are still one of the leading causes for death after heart diseases and cancer in all over the world. Most strokes happen because an artery that carries blood uphill from the heart to the head gets clogged. Most of the time, as with…

组织与器官 · 定量生物学 2020-02-03 Nurullah Arslan , Kazim Besirli , Gurcan Comert , Omer F Beyca

In this work we develop a homogenisation methodology to upscale mathematical descriptions of microcirculatory blood flow from the microscale (where individual vessels are resolved) to the macroscopic (or tissue) scale. Due to the assumed…

组织与器官 · 定量生物学 2024-01-23 Y. Ben-Ami , B. D. Wood , J. M. Pitt-Francis , P. K. Maini , H. M. Byrne

Cerebral autoregulation plays a key physiological role by limiting blood flow changes in the face of pressure fluctuations. Although the involved cellular processes are mechanically driven, the quantification of haemodynamic forces in…

定量方法 · 定量生物学 2024-11-15 Alberto Coccarelli , Ioannis Polydoros , Alex Drysdale , Osama F. Harraz , Chennakesava Kadapa

In this work, we propose a novel approach which combines ultrasound with Eulerian and Lagrangian descriptors, to analyse blood flow dynamics and fluid transport in stenotic aortic models with morphology, mechanical and optical properties…

流体动力学 · 物理学 2021-01-05 Javier Brum , Miguel Bernal , Nicasio Barrere , Carlos Negreira , Cecilia Cabeza

Dense granular flows exhibit both surface deformation and secondary flows due to the presence of normal stress differences. Yet, a complete mathematical modelling of these two features is still lacking. This paper focuses on a steady…

流体动力学 · 物理学 2025-07-01 C. Gadal , C. G. Johnson , J. M. N. T. Gray