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This thesis develops computational methods in similarity-preserving hashing, classification, and cancer genomics. Standard space partitioning-based hashing relies on Binary Search Trees (BSTs), but their exponential growth and sparsity…

机器学习 · 计算机科学 2025-08-26 Prashant Gupta

Biclustering is the task of simultaneously clustering the rows and columns of the data matrix into different subgroups such that the rows and columns within a subgroup exhibit similar patterns. In this paper, we consider the case of…

机器学习 · 计算机科学 2022-01-31 Nicolas Fraiman , Zichao Li

We present a new approach for the analysis of genome-wide expression data. Our method is designed to overcome the limitations of traditional techniques, when applied to large-scale data. Rather than alloting each gene to a single cluster,…

生物物理 · 物理学 2009-11-07 Sven Bergmann , Jan Ihmels , Naama Barkai

Subspace clustering assumes that the data is sepa-rable into separate subspaces. Such a simple as-sumption, does not always hold. We assume that, even if the raw data is not separable into subspac-es, one can learn a representation…

机器学习 · 计算机科学 2019-12-11 Jyoti Maggu , Angshul Majumdar , Emilie Chouzenoux

Deep clustering as an important branch of unsupervised representation learning focuses on embedding semantically similar samples into the identical feature space. This core demand inspires the exploration of contrastive learning and…

计算机视觉与模式识别 · 计算机科学 2024-04-16 Haifeng Xia , Hai Huang , Zhengming Ding

Genetic Algorithms (GAs) are explored as a tool for probing new physics with high dimensionality. We study the 19-dimensional pMSSM, including experimental constraints from all sources and assessing the consistency of potential signals of…

高能物理 - 唯象学 · 物理学 2018-05-14 Steven Abel , David G. Cerdeno , Sandra Robles

Data clustering is a recognized data analysis method in data mining whereas K-Means is the well known partitional clustering method, possessing pleasant features. We observed that, K-Means and other partitional clustering techniques suffer…

神经与进化计算 · 计算机科学 2014-02-27 Jayshree Ghorpade-Aher , Vishakha A. Metre

State-of-the-art clustering algorithms use heuristics to partition the feature space and provide little insight into the rationale for cluster membership, limiting their interpretability. In healthcare applications, the latter poses a…

机器学习 · 统计学 2018-12-04 Dimitris Bertsimas , Agni Orfanoudaki , Holly Wiberg

Subspace clustering is a classical unsupervised learning task, built on a basic assumption that high-dimensional data can be approximated by a union of subspaces (UoS). Nevertheless, the real-world data are often deviating from the UoS…

计算机视觉与模式识别 · 计算机科学 2025-03-24 Xianghan Meng , Zhiyuan Huang , Wei He , Xianbiao Qi , Rong Xiao , Chun-Guang Li

Gene expression profiles are essential in identifying different cancer phenotypes. Clustering gene expression datasets can provide accurate identification of cancerous cell lines, but this task is challenging due to the small sample size…

生物物理 · 物理学 2023-05-30 Yuchen Wu , Luke Dicks , David J. Wales

Clustering is an important technique for identifying structural information in large-scale data analysis, where the underlying dataset may be too large to store. In many applications, recent data can provide more accurate information and…

数据结构与算法 · 计算机科学 2023-11-02 David P. Woodruff , Peilin Zhong , Samson Zhou

Kiwi is a minimalist and extendable Constraint Programming (CP) solver specifically designed for education. The particularities of Kiwi stand in its generic trailing state restoration mechanism and its modulable use of variables. By…

人工智能 · 计算机科学 2017-05-03 Renaud Hartert

Clustering is a central tool in biomedical research for discovering heterogeneous patient subpopulations, where group boundaries are often diffuse rather than sharply separated. Traditional methods produce hard partitions, whereas soft…

统计方法学 · 统计学 2026-01-07 Qiuyi Wu , Zihan Zhu , Anru R. Zhang

Microarray technology is a process that allows thousands of genes simultaneously monitor to various experimental conditions. It is used to identify the co-expressed genes in specific cells or tissues that are actively used to make proteins,…

计算工程、金融与科学 · 计算机科学 2013-07-16 T. Chandrasekhar , K. Thangavel , E. Elayaraja

Cancer is a number of related yet highly heterogeneous diseases. Correct identification of cancer subtypes is critical for clinical decisions. The advance in sequencing technologies has made it possible to study cancer based on abundant…

应用统计 · 统计学 2018-11-27 Xiaochun Chen , Honggang Wang , Donghui Yan

We develop an iterative subsampling approach to improve the computational efficiency of our previous work on solution path clustering (SPC). The SPC method achieves clustering by concave regularization on the pairwise distances between…

统计方法学 · 统计学 2016-09-16 Yuliya Marchetti , Qing Zhou

Microarrays are made it possible to simultaneously monitor the expression profiles of thousands of genes under various experimental conditions. It is used to identify the co-expressed genes in specific cells or tissues that are actively…

机器学习 · 计算机科学 2012-03-15 T. Chandrasekhar , K. Thangavel , E. Elayaraja

Clustering is a fundamental tool in unsupervised learning, used to group objects by distinguishing between similar and dissimilar features of a given data set. One of the most common clustering algorithms is k-means. Unfortunately, when…

机器学习 · 统计学 2021-08-17 Olga Dorabiala , J. Nathan Kutz , Aleksandr Aravkin

Clustering is a powerful and extensively used data science tool. While clustering is generally thought of as an unsupervised learning technique, there are also supervised variations such as Spath's clusterwise regression that attempt to…

机器学习 · 计算机科学 2023-05-09 Aravinth Chembu , Scott Sanner

Variance reduction techniques such as SPIDER/SARAH/STORM have been extensively studied to improve the convergence rates of stochastic non-convex optimization, which usually maintain and update a sequence of estimators for a single function…

机器学习 · 计算机科学 2023-01-02 Wei Jiang , Gang Li , Yibo Wang , Lijun Zhang , Tianbao Yang