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Consider two independent random strings having same length and taking values uniformly in a common finite alphabet. We study the order of the variance of the length of the longest common subsequences (LCS) of these strings when long blocks,…

概率论 · 数学 2016-09-26 S. Amsalu , C. Houdré , H. Matzinger

Maximal Common Subsequences (MCSs) between two strings X and Y are subsequences of both X and Y that are maximal under inclusion. MCSs relax and generalize the well known and widely used concept of Longest Common Subsequences (LCSs), which…

数据结构与算法 · 计算机科学 2023-07-26 Alessio Conte , Roberto Grossi , Giulia Punzi , Takeaki Uno

Sequence comparison is a widely used computational technique in modern molecular biology. In spite of the frequent use of sequence comparisons the important problem of assigning statistical significance to a given degree of similarity is…

定量方法 · 定量生物学 2007-05-23 Ralf Bundschuh , Nicholas Chia

A classical measure of string comparison is given by the longest common subsequence (LCS) problem on a pair of strings. We consider its generalisation, called the semi-local LCS problem, which arises naturally in many string-related…

数据结构与算法 · 计算机科学 2015-03-13 Alexander Tiskin

In this work, we consider a variant of the classical Longest Common Subsequence problem called Doubly-Constrained Longest Common Subsequence (DC-LCS). Given two strings s1 and s2 over an alphabet A, a set C_s of strings, and a function Co…

数据结构与算法 · 计算机科学 2013-11-20 Paola Bonizzoni , Gianluca Della Vedova , Riccardo Dondi , Yuri Pirola

We consider the longest common subsequence (LCS) problem with the restriction that the common subsequence is required to consist of at least $k$ length substrings. First, we show an $O(mn)$ time algorithm for the problem which gives a…

A repetition free Longest Common Subsequence (LCS) of two sequences x and y is an LCS of x and y where each symbol may appear at most once. Let R denote the length of a repetition free LCS of two sequences of n symbols each one chosen…

组合数学 · 数学 2013-05-22 Marcos Kiwi , Cristina G. Fernandes

One of the most critical problems in the field of string algorithms is the longest common subsequence problem (LCS). The problem is NP-hard for an arbitrary number of strings but can be solved in polynomial time for a fixed number of…

分布式、并行与集群计算 · 计算机科学 2023-09-19 Soroush Vahidi , Baruch Schieber , Zhihui Du , David A. Bader

Finding an Approximate Longest Common Substring (ALCS) within a given set $S=\{s_1,s_2,\ldots,s_m\}$ of $m \ge 2$ strings is a key problem in computational biology, such as identifying related mutations across multiple genetic sequences. We…

数据结构与算法 · 计算机科学 2025-09-22 Hamed Hasibi , Neerja Mhaskar , W. F. Smyth

The rapid development of high-throughput sequencing technologies has led to an explosive increase in biological sequence data, making sequence clustering a fundamental task in large-scale bioinformatics analyses. Unlike traditional…

基因组学 · 定量生物学 2026-01-22 Simeng Zhang , Xinying Liu , Jun Lou , Mudi Jiang , Quan Zou , Zengyou He

Computational methods for discovering patterns of local correlations in sequences are important in computational biology. Here we show how to determine the optimal partitioning of aligned sequences into non-overlapping segments such that…

计算工程、金融与科学 · 计算机科学 2012-06-26 Joseph Bockhorst , Nebojsa Jojic

The alignment of biological sequences such as DNA, RNA, and proteins, is one of the basic tools that allow to detect evolutionary patterns, as well as functional/structural characterizations between homologous sequences in different…

定量方法 · 定量生物学 2023-05-01 Louise Budzynski , Andrea Pagnani

Given two sequences $A[1..n]$ and $B[1..m]$ over a totally ordered alphabet, the \emph{Longest Common Bitonic Subsequence} (LCBS) problem asks for a longest common subsequence that is strictly increasing up to a single peak element and…

数据结构与算法 · 计算机科学 2026-01-15 Md. Tanzeem Rahat , Md. Manzurul Hasan

Multiple sequence alignment (MSA) has been one of the most important problems in bioinformatics for more decades and it is still heavily examined by many mathematicians and biologists. However, mostly because of the practical motivation of…

定量方法 · 定量生物学 2015-11-17 Kristóf Takács

Given a set of $k$ strings $I$, their longest common subsequence (LCS) is the string with the maximum length that is a subset of all the strings in $I$. A data-structure for this problem preprocesses $I$ into a data-structure such that the…

数据结构与算法 · 计算机科学 2021-01-13 Sepideh Aghamolaei

The problem of finding the longest common subsequence (LCS) for a set of sequences is a very interesting and challenging problem in computer science. This problem is NP-complete, but because of its importance, many heuristic algorithms have…

数据结构与算法 · 计算机科学 2009-06-30 Kang Ning

The Longest Common Subsequence (LCS) of two strings is a fundamental string similarity measure with a classical dynamic programming solution taking quadratic time. Despite significant efforts, little progress was made in improving the…

数据结构与算法 · 计算机科学 2021-12-17 Negev Shekel Nosatzki

This paper investigates the approximability of the Longest Common Subsequence (LCS) problem. The fastest algorithm for solving the LCS problem exactly runs in essentially quadratic time in the length of the input, and it is known that under…

数据结构与算法 · 计算机科学 2021-05-10 Shyan Akmal , Virginia Vassilevska Williams

The Shortest Common Superstring (SCS) problem is a fundamental task in sequence analysis. In genome assembly, however, the double-stranded nature of DNA implies that each fragment may occur either in its original orientation or as its…

数据结构与算法 · 计算机科学 2026-03-30 Ryosuke Yamano , Tetsuo Shibuya

In this paper we define a new problem, motivated by computational biology, $LCSk$ aiming at finding the maximal number of $k$ length $substrings$, matching in both input strings while preserving their order of appearance. The traditional…

数据结构与算法 · 计算机科学 2014-02-11 Gary Benson , Avivit Levy , Riva Shalom