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Extracting activation patterns from functional Magnetic Resonance Images (fMRI) datasets remains challenging in rapid-event designs due to the inherent delay of blood oxygen level-dependent (BOLD) signal. The general linear model (GLM)…

机器学习 · 计算机科学 2013-05-14 Fabian Pedregosa , Michael Eickenberg , Bertrand Thirion , Alexandre Gramfort

Sparse dictionary learning is a popular method for representing signals as linear combinations of a few elements from a dictionary that is learned from the data. In the classical setting, signals are represented as vectors and the…

最优化与控制 · 数学 2019-09-20 Evan Schwab , Benjamin D. Haeffele , René Vidal , Nicolas Charon

Functional connectivity (FC) derived from resting-state fMRI plays a critical role in personalized predictions such as age and cognitive performance. However, applying foundation models(FM) to fMRI data remains challenging due to its high…

神经元与认知 · 定量生物学 2025-08-26 Yanwen Wang , Xinglin Zhao , Yijin Song , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

Whenever data-based systems are employed in engineering applications, defining an optimal statistical representation is subject to the problem of model selection. This paper focusses on how well models can generalise in Structural Health…

机器学习 · 统计学 2025-01-15 C. A. Lindley , N. Dervilis , K. Worden

Quantitative magnetic resonance imaging (qMRI) is increasingly investigated for use in a variety of clinical tasks from diagnosis, through staging, to treatment monitoring. However, experiment design in qMRI, the identification of the…

计算机视觉与模式识别 · 计算机科学 2024-08-23 Tianshu Zheng , Zican Wang , Timothy Bray , Daniel C. Alexander , Dan Wu , Hui Zhang

Large language models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence technology which is rapidly evolving and promises to aid in medical diagnosis. However, the correctness and the accuracy of their returns has…

计算与语言 · 计算机科学 2024-02-07 Dimitrios P. Panagoulias , Maria Virvou , George A. Tsihrintzis

In optimizing real-world structures, due to fabrication or budgetary restraints, the design variables may be restricted to a set of standard engineering choices. Such variables, commonly called categorical variables, are discrete and…

计算工程、金融与科学 · 计算机科学 2025-01-03 Mehran Ebrahimi , Hyunmin Cheong , Pradeep Kumar Jayaraman , Farhad Javid

Recent advances in multimodal large language models (LLMs) have enabled unified reasoning across images, audio, and video, but extending such capability to brain imaging remains largely unexplored. Bridging this gap is essential to link…

计算与语言 · 计算机科学 2026-05-15 Yuxiang Wei , Yanteng Zhang , Xi Xiao , Chengxuan Qian , Tianyang Wang , Vince D. Calhoun

Structural matrix-variate observations routinely arise in diverse fields such as multi-layer network analysis and brain image clustering. While data of this type have been extensively investigated with fruitful outcomes being delivered, the…

统计理论 · 数学 2022-01-25 Zhongyuan Lyu , Dong Xia

Sparse regularized regression methods are now widely used in genome-wide association studies (GWAS) to address the multiple testing burden that limits discovery of potentially important predictors. Linear mixed models (LMMs) have become an…

统计方法学 · 统计学 2022-06-27 Julien St-Pierre , Karim Oualkacha , Sahir Rai Bhatnagar

High-dimensional sparse generalized linear models (GLMs) have emerged in the setting that the number of samples and the dimension of variables are large, and even the dimension of variables grows faster than the number of samples. False…

统计理论 · 数学 2021-05-04 Chang Cui , Jinzhu Jia , Yijun Xiao , Huiming Zhang

Resting-state functional magnetic resonance imaging (rs-fMRI) can reflect spontaneous neural activities in brain and is widely used for brain disorder analysis.Previous studies propose to extract fMRI representations through diverse…

定量方法 · 定量生物学 2023-06-27 Qianqian Wang , Wei Wang , Yuqi Fang , P. -T. Yap , Hongtu Zhu , Hong-Jun Li , Lishan Qiao , Mingxia Liu

Computational models of biophysical tissue properties have been widely used in diffusion MRI (dMRI) research to elucidate the link between microstructural properties and MR signal formation. For brain tissue, the research community has…

医学物理 · 物理学 2019-07-16 Santiago Coelho , Jose M. Pozo , Sune N. Jespersen , Alejandro F. Frangi

We investigate a general matrix factorization for deviance-based data losses, extending the ubiquitous singular value decomposition beyond squared error loss. While similar approaches have been explored before, our method leverages…

机器学习 · 统计学 2023-07-04 Liang Wang , Luis Carvalho

We present a framework for the automated measurement of responsible AI (RAI) metrics for large language models (LLMs) and associated products and services. Our framework for automatically measuring harms from LLMs builds on existing…

Conditional medical image generation plays an important role in many clinically relevant imaging tasks. However, existing methods still face a fundamental challenge in balancing inference efficiency, patient-specific fidelity, and…

计算机视觉与模式识别 · 计算机科学 2026-04-22 Zirong Li , Siyuan Mei , Weiwen Wu , Andreas Maier , Lina Gölz , Yan Xia

We propose a new sparse estimation method, termed MIC (Minimum approximated Information Criterion), for generalized linear models (GLM) in fixed dimensions. What is essentially involved in MIC is the approximation of the $\ell_0$-norm with…

统计方法学 · 统计学 2018-07-23 Xiaogang Su , Juanjuan Fan , Richard A. Levine , Martha E. Nunn , Chih-Ling Tsai

We present a novel statistical framework for analyzing stereotypes in large language models (LLMs) by systematically estimating the bias and variation in their generation. Current alignment evaluation metrics often overlook stereotypes'…

计算与语言 · 计算机科学 2025-05-27 Yiran Liu , Ke Yang , Zehan Qi , Xiao Liu , Yang Yu , ChengXiang Zhai

Estimating graphical model structure from high-dimensional and undersampled data is a fundamental problem in many scientific fields. Existing approaches, such as GLASSO, latent variable GLASSO, and latent tree models, suffer from high…

机器学习 · 统计学 2019-09-18 Greg Ver Steeg , Hrayr Harutyunyan , Daniel Moyer , Aram Galstyan

Brain networks has attracted the interests of many neuroscientists. From functional MRI (fMRI) data, statistical tools have been developed to recover brain networks. However, the dimensionality of whole-brain fMRI, usually in hundreds of…

统计方法学 · 统计学 2014-04-08 Xi Luo