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Mental stress is a vague though familiar concept that accounts for an agency of the good, the bad and the ugly, that operates in the brains of animated beings, in response to environmental stressors. In this work, we provide evidence for…
Anxiety, the anticipatory unease about a potential negative outcome, is a common and beneficial human emotion. However, there is still much that is not known, such as how anxiety relates to our body and how it manifests in language. This is…
All self-active living beings need to solve the motivational problem: The question what to do at any moment of their live. For humans and non-human animals at least two distinct layers of motivational drives are known, the primary needs for…
Impulsive individuals exhibit abnormal reward processing (heightened preference for immediate rewards, i.e., impulsive choice, IC) and a penchant for maladaptive action (the inability to inhibit inappropriate actions, i.e., impulsive…
Understanding and mitigating drivers' negative emotions, stress levels, and anxiety is of high importance for decreasing accident rates, and enhancing road safety. While detecting drivers' stress and negative emotions can significantly help…
Distress is a complex condition which affects a significant percentage of cancer patients and may lead to depression, anxiety, sadness, suicide and other forms of psychological morbidity. Compelling evidence supports screening for distress…
Animal models indicate that motor behaviour is shaped by monoamine neurotransmitters released diffusely throughout the brain and spinal cord. We present strong evidence that human motor pathways are equally affected by neuromodulation…
Danger requires a strong rapid response. Speedy triggers are prone to false signals. False alarms can be costly, requiring strong negative regulators to oppose the initial triggers. Strongly opposed forces can easily be perturbed, leading…
Major depressive disorder (MDD) is a debilitating health condition affecting a substantial part of the world's population. At present, there is no biological theory of MDD, and treatment is partial at best. Here I present a theory of MDD…
More than 60% of individuals recovering from substance use disorder relapse within one year. Some will resume drug consumption even after decades of abstinence. The cognitive and psychological mechanisms that lead to relapse are not…
Both neurobiological and environmental factors are known to play a role in the origin of schizophrenia, but no model has been proposed that accounts for both. This work presents a functional model of schizophrenia that merges psychodynamic…
Emotional disorders and psychological flourishing are the result of complex interactions between positive and negative affects that depend on external events and the subject's internal representations. Based on psychological data, we…
Several studies have been reported in the literature for the automatic detection of mental disorders. It is reported that mental disorders are highly correlated. The exploration of this fact for the automatic detection of mental disorders…
Emotion plays an important role in human cognition and performance. Motivated by this, we investigate whether analogous emotional signals can shape the behavior of large language models (LLMs) and agents. Existing emotion-aware studies…
Research in psychopathology has shown that, at an aggregate level, the patterns of emotional change over time -- emotion dynamics -- are indicators of one's mental health. One's patterns of emotion change have traditionally been determined…
This work presents a comprehensive theory of consciousness grounded in mathematical formalism and supported by clinical data analysis. The framework developed herein demonstrates that consciousness exists as a continuous, non-monotonic…
It is obvious that emotions are causal variables of motivation, as they elicit states, forces and energies that trigger and guide labor behavior. Thus, a motivational tension that is not informed by needs alone, but also by emotions,…
Suicidal behavior is a leading cause of injury and death worldwide. Suicide has been associated with psychiatric illnesses such as depression and schizophrenia, as well as economic uncertainty, and social/cultural factors. This study…
Humans have employed an incredible variety of plant-derived substances over the millennia in order to alter consciousness and perception. Among the innumerable narcotics, analgesics, 'ordeal' drugs, and other psychoactive substances…
Stressors are related to depression, but this relationship is complex. We investigate the relationship between open-ended text responses about stressors and depressive symptoms across gender and racial/ethnic groups. First, we use topic…