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Proposals to determine biomolecular structures from diffraction experiments using femtosecond X-ray free-electron laser (XFEL) pulses involve a conflict between the incident brightness required to achieve diffraction-limited atomic…

光学 · 物理学 2015-05-19 Harry M. Quiney , Keith A. Nugent

In single particle coherent x-ray diffraction imaging experiments, performed at x-ray free-electron lasers (XFELs), samples are exposed to intense x-ray pulses to obtain single-shot diffraction patterns. The high intensity induces…

原子与分子团簇 · 物理学 2013-01-29 U. Lorenz , N. M. Kabachnik , E. Weckert , I. A. Vartanyants

The routine atomic-resolution structure determination of single particles is expected to have profound implications for probing the structure-function relationship in systems ranging from energy materials to biological molecules.…

Serial femtosecond X-ray crystallography (SFX) captures the structure and dynamics of biological macromolecules at high spatial and temporal resolutions. The ultrashort pulse produced by an X-ray free electron laser (XFEL) 'outruns' much of…

等离子体物理 · 物理学 2025-06-03 Spencer K. Passmore , Alaric L. Sanders , Andrew V. Martin , Harry M. Quiney

The ingenious idea of single molecule imaging by hard x-ray Free Electron Laser (X-FEL) pulses was recently proposed by Neutze et al. [Nature,406,752(2000)]. However, in their numerical modelling of the Coulomb explosion several…

凝聚态物理 · 物理学 2009-11-10 Zoltan Jurek , Gabor Oszlanyi , Gyula Faigel

X-ray Free Electron Lasers (XFEL) are revolutionary photons sources, whose ultrashort, brilliant pulses are expected to allow single molecule diffraction experiments providing structural information on the atomic length scale. This ultimate…

光学 · 物理学 2015-05-20 Andrea Fratalocchi , Giancarlo Ruocco

Coherent diffraction imaging (CDI) of single molecules at atomic resolution is a major goal for the x-ray free electron lasers (XFELs). However, during an imaging pulse, the fast laser-induced ionization may strongly affect the recorded…

介观与纳米尺度物理 · 物理学 2015-06-05 Zoltan Jurek , Robert Thiele , Beata Ziaja , Robin Santra

X-ray free-electron lasers (FELs) are promising tools for structural determination of macromolecules via coherent x-ray scattering. During ultrashort and ultraintense x-ray pulses with an atomic scale wavelength, samples are subject to…

原子物理 · 物理学 2011-10-18 Sang-Kil Son , Linda Young , Robin Santra

Effects of plasma inhomogeneity on self-modulating proton bunches and accelerated electrons were studied numerically. The main effect is the change of the wakefield wavelength which results in phase shifts and loss of accelerated particles.…

等离子体物理 · 物理学 2013-07-16 K. V. Lotov , A. Pukhov , A. Caldwell

Imaging of the structure of single proteins or other biomolecules with atomic resolution would be enormously beneficial to structural biology. X-ray free-electron lasers generate highly intense and ultrashort x-ray pulses, providing a route…

原子物理 · 物理学 2014-07-30 Jan Malte Slowik , Sang-Kil Son , Gopal Dixit , Zoltan Jurek , Robin Santra

The structures, as building-blocks for designing functional nanomaterials, have fueled the development of versatile nanoprobes to understand local structures of noncrystalline specimens. Progresses in analyzing structures of individual…

We theoretically study the propagation of light through a cold atomic medium, where the effects of motion, laser intensity, atomic density, and polarization can all modify the properties of the scattered light. We present two different…

量子物理 · 物理学 2016-08-24 Bihui Zhu , John Cooper , Jun Ye , Ana Maria Rey

Single-particle imaging experiments of biomolecules at x-ray free-electron lasers (XFELs) require processing of hundreds of thousands (or more) of images that contain very few x-rays. Each low-flux image of the diffraction pattern is…

仪器与探测器 · 物理学 2012-03-16 Hugh T. Philipp , Kartik Ayyer , Mark W. Tate , Veit Elser , Sol M. Gruner

A new scheme based on (i) upcoming brilliant X-ray Free Electron Laser (FEL) sources, (ii) novel energy and angular dispersive, large-area electron imagers and (iii) the well-known photoelectron holography is elaborated that provides…

原子物理 · 物理学 2015-05-14 F. Krasniqi , B. Najjari , L. Strüder , D. Rolles , A. Voitkiv , J. Ullrich

Free-electron lasers (FEL) in the extreme ultraviolet (XUV) and X-ray regime opened up the possibility for experiments at high power densities, in particular allowing for fluence-dependent absorption and scattering experiments to reveal…

Using a quantum electrodynamic framework, we calculate the off-resonant scattering of a broad-band X-ray pulse from a sample initially prepared in an arbitrary superposition of electronic states. The signal consists of single-particle…

化学物理 · 物理学 2015-06-19 Kochise Bennett , Jason D. Biggs , Yu Zhang , Konstantin E. Dorfman , Shaul Mukamel

X-ray free-electron lasers (XFELs) produce X-ray pulses with high brilliance and short pulse duration. These properties enable structural investigations of biomolecular nanocrystals, and they allow resolving the dynamics of biomolecules…

化学物理 · 物理学 2022-08-05 Leonie Chatzimagas , Jochen S. Hub

One of the options for increasing longitudinal coherency of X-ray free electron lasers (XFELs) is their seeding with microbunched electron beam. Several schemes leading to significant amplitude of the beam bunching at X-ray wavelengths were…

加速器物理 · 物理学 2012-07-23 Nikolai A. Yampolsky , Bruce E. Carlsten

Since the work of Anderson on localization, interference effects for the propagation of a wave in the presence of disorder have been extensively studied, as exemplified in coherent backscattering (CBS) of light. In the multiple scattering…

量子物理 · 物理学 2009-11-07 Cord A. Mueller , Thibaut Jonckheere , Christian Miniatura , Dominique Delande

The spatial inhomogeneities are expected to affect nucleation process in an essential way. These effects are studied theoretically by considering the case of the depinning of the charge density wave as a typical example. The threshold field…

无序系统与神经网络 · 物理学 2009-10-31 Masanori Yumoto , Hidetoshi Fukuyama , Hiroshi Matsukawa
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