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When employing mechanistic models to study biological phenomena, practical parameter identifiability is important for making accurate predictions across wide range of unseen scenarios, as well as for understanding the underlying mechanisms.…

定量方法 · 定量生物学 2023-10-19 Yue Liu , Kevin Suh , Philip K. Maini , Daniel J. Cohen , Ruth E. Baker

In this work, we define a practical identifiability criterion, (e, q)-identifiability, based on a parameter e, reflecting the noise in observed variables, and a parameter q, reflecting the mean-square error of the parameter estimator. This…

统计方法学 · 统计学 2026-03-13 Nora Heitzman-Breen , Vanja Dukic , David M. Bortz

Statistical latent class models are widely used in social and psychological researches, yet it is often difficult to establish the identifiability of the model parameters. In this paper we consider the identifiability issue of a family of…

统计方法学 · 统计学 2016-03-15 Gongjun Xu

Reliable predictions from systems biology models require knowing whether parameters can be estimated from available data, and with what certainty. Identifiability analysis reveals whether parameters are learnable in principle (structural…

This paper studies identifiability and convergence behaviors for parameters of multiple types in finite mixtures, and the effects of model fitting with extra mixing components. First, we present a general theory for strong identifiability,…

统计理论 · 数学 2015-01-13 Nhat Ho , XuanLong Nguyen

Advances in machine learning technologies have led to increasingly powerful models in particular in the context of big data. Yet, many application scenarios demand for robustly interpretable models rather than optimum model accuracy; as an…

机器学习 · 计算机科学 2020-05-07 Lukas Pfannschmidt , Jonathan Jakob , Fabian Hinder , Michael Biehl , Peter Tino , Barbara Hammer

Scientists use mathematical modelling to understand and predict the properties of complex physical systems. In highly parameterised models there often exist relationships between parameters over which model predictions are identical, or…

数据分析、统计与概率 · 物理学 2017-03-24 Dhruva V. Raman , James Anderson , Antonis Papachristodoulou

Researchers develop models to explain the unknowns. These models typically involve parameters that capture tangible quantities, the estimation of which is desired. Parameter identifiability investigates the recoverability of the unknown…

最优化与控制 · 数学 2024-07-01 Anuththara Sarathchandra , Azadeh Aghaeeyan , Pouria Ramazi

Computational inverse problems for biomedical simulators suffer from limited data and relatively high parameter dimensionality. This often requires sensitivity analysis, where parameters of the model are ranked based on their influence on…

组织与器官 · 定量生物学 2025-06-06 Mitchel J. Colebank

Latent class models have wide applications in social and biological sciences. In many applications, pre-specified restrictions are imposed on the parameter space of latent class models, through a design matrix, to reflect practitioners'…

统计理论 · 数学 2019-06-03 Yuqi Gu , Gongjun Xu

We study the identifiability of parameters and falsifiability of predictions under the process of model expansion in a Bayesian setting. Identifiability is represented by the closeness of the posterior to the prior distribution and…

统计理论 · 数学 2025-10-15 Collin Cademartori

Identifiability is a desirable property of a statistical model: it implies that the true model parameters may be estimated to any desired precision, given sufficient computational resources and data. We study identifiability in the context…

机器学习 · 统计学 2020-07-09 Geoffrey Roeder , Luke Metz , Diederik P. Kingma

I study partial identification of distributional parameters in triangular systems. This model consists of a nonparametric outcome equation and a selection equation. This allows for general unobserved heterogeneity and selection on…

统计方法学 · 统计学 2014-11-11 Ju Hyun Kim

Interpreting data with mathematical models is an important aspect of real-world industrial and applied mathematical modeling. Often we are interested to understand the extent to which a particular set of data informs and constrains model…

统计方法学 · 统计学 2025-03-06 Matthew J Simpson , Ruth E Baker

To better understand complexity in neural networks, we theoretically investigate the idealised phenomenon of lossless network compressibility, whereby an identical function can be implemented with fewer hidden units. In the setting of…

机器学习 · 计算机科学 2024-05-27 Matthew Farrugia-Roberts

We characterize those ex-ante restrictions on the random utility model which lead to identification. We first identify a simple class of perturbations which transfer mass from a suitable pair of preferences to the pair formed by swapping…

理论经济学 · 经济学 2024-08-14 Peter P. Caradonna , Christopher Turansick

We analyze the information-theoretic limits for the recovery of node labels in several network models. This includes the Stochastic Block Model, the Exponential Random Graph Model, the Latent Space Model, the Directed Preferential…

机器学习 · 计算机科学 2019-05-28 Chuyang Ke , Jean Honorio

We extend the Levenberg-Marquardt method on Euclidean spaces to Riemannian manifolds. Although a Riemannian Levenberg-Marquardt (RLM) method was produced by Peeters in 1993, to the best of our knowledge, there has been no analysis of…

最优化与控制 · 数学 2023-07-18 Sho Adachi , Takayuki Okuno , Akiko Takeda

The condition of parameter identifiability is essential for the consistency of all estimators and is often challenging to prove. As a consequence, this condition is often assumed for simplicity although this may not be straightforward to…

统计理论 · 数学 2016-07-21 Stéphane Guerrier , Roberto Molinari

This chapter reviews the microeconometrics literature on partial identification, focusing on the developments of the last thirty years. The topics presented illustrate that the available data combined with credible maintained assumptions…

计量经济学 · 经济学 2020-04-27 Francesca Molinari