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Cardiac disease and clinical intervention may both lead to an increased risk for thrombosis events due to modified blood flow in the heart, and thereby a change in the mechanical stimuli of blood cells passing through the chambers of the…

We consider a fully-connected network of leaky integrate-and-fire neurons with spike-timing-dependent plasticity. The plasticity is controlled by a parameter representing the expected weight of a synapse between neurons that are firing…

神经元与认知 · 定量生物学 2011-09-23 Chun-Chung Chen , David Jasnow

In the paper we study the impact of the boundary vorticity distribution on the dynamics of enstrophy for flows around streamlined body. A new energy identity is derived in the article, which includes the boundary values of the vortex…

偏微分方程分析 · 数学 2026-05-14 Aleksei Gorshkov

Intracranial aneurysms are the leading cause of hemorrhagic stroke. One of the established treatment approaches is the embolization induced by coil insertion. However, the prediction of treatment and subsequent changed flow characteristics…

数值分析 · 数学 2026-05-20 Medeea Horvat , Stephan B. Lunowa , Dmytro Sytnyk , Barbara Wohlmuth

The relationship between blood flow and neuronal activity is widely recognized, with blood flow frequently serving as a surrogate for neuronal activity in fMRI studies. At the microscopic level, neuronal activity has been shown to influence…

神经元与认知 · 定量生物学 2023-06-29 Yoni Choukroun , Lior Golgher , Pablo Blinder , Lior Wolf

We analyse mathematical models in order to understand how microstructural features of vascular networks may affect blood-flow dynamics, and to identify particular characteristics that promote the onset of self-sustained oscillations. By…

定量方法 · 定量生物学 2022-06-23 Yaron Ben-Ami , George W. Atkinson , Joe M. Pitt-Francis , Philip K. Maini , Helen M. Byrne

Hemostasis and thrombosis are often thought as two sides of the same clotting mechanism whereas hemostasis is a natural protective mechanism to prevent bleeding and thrombosis is a blood clot abnormally formulated inside a blood vessel,…

组织与器官 · 定量生物学 2019-11-19 Limei Cheng , Guo-Wei Wei , Tarek Leil

Flow networks are essential for both living organisms and enginneered systems. These networks often present complex dynamics controlled, at least in part, by their topology. Previous works have shown that topologically complex networks…

软凝聚态物质 · 物理学 2020-03-24 Miguel Ruiz-Garcia , Eleni Katifori

Correlating neural communication in brain networks with behavior and cognition can provide fundamental insights into the functionality of both healthy and diseased brains. We demonstrate how communication in the brain can be estimated from…

信号处理 · 电气工程与系统科学 2023-06-21 Felix Schwock , Julien Bloch , Les Atlas , Shima Abadi , Azadeh Yazdan-Shahmorad

A nucleation model for the breakdown phenomenon in freeway free traffic flow at an on-ramp bottleneck is presented. This model, which can explain empirical results on the breakdown phenomenon, is based on assumptions of three-phase traffic…

统计力学 · 物理学 2007-05-23 Boris S. Kerner , Sergey L. Klenov

As a dynamical complex system, traffic is characterized by a transition from free flow to congestions, which is mostly studied in highways. However, despite its importance in developing congestion mitigation strategies, the understanding of…

物理与社会 · 物理学 2015-12-02 Feilong Wang , Daqing Li , Xiaoyun Xu , Ruoqian Wu , Shlomo Havlin

In cerebrovascular networks, some vertices are more connected to each other than with the rest of the vasculature, defining a community structure. Here, we introduce a class of model networks built by rewiring Random Regular Graphs, which…

生物物理 · 物理学 2022-07-19 Florian Goirand , Bertrand Georgeot , Olivier Giraud , Sylvie Lorthois

We introduce a cellular automaton model coupled with a transport equation for flows on graphs. The direction of the flow is described by a switching process where the switching probability dynamically changes according to the value of the…

元胞自动机与格子气 · 物理学 2013-07-02 Pierre Degond , Michael Herty , Jian-Guo Liu

A constitutive relation between stress and strain relative to a reference state is the basic assumption of elasticity theory. However, in living matter, force generation is governed by motor molecule activity, which does not depend on…

软凝聚态物质 · 物理学 2026-03-17 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

Previous studies on peristalsis, the pumping of fluid along a channel by wave-like displacements of the channel walls, have shown that the elastic properties of the channel and the peristaltic wave shape can influence the flow rate.…

流体动力学 · 物理学 2025-08-12 Avery Trevino , Thomas R. Powers , Roberto Zenit , Mauro Rodriguez

Background and Objective: This proof of concept study investigates mathematical modelling of blood flow and oxygen transport in cerebral microcirculation, focusing on understanding hemodynamic responses. By coupling oxygen transport models…

数值分析 · 数学 2024-11-19 Maryam Samavaki , Santtu Söderholm , Arash Zarrin Nia , Sampsa Pursiainen

Entropy is a classical measure to quantify the amount of information or complexity of a system. Various entropy-based measures such as functional and spectral entropies have been proposed in brain network analysis. However, they are less…

神经元与认知 · 定量生物学 2018-03-08 Hyekyoung Lee , Eunkyung Kim , Hyejin Kang , Youngmin Huh , Youngjo Lee , Seonhee Lim , Dong Soo Lee

In nonlinear systems, small perturbations are conventionally attributed to negligible nonlinearity, justifying linear approximations. Here, we uncover a notable exception to this paradigm in an electrokinetic (EK) flow. Using a novel dual…

流体动力学 · 物理学 2026-04-16 Jin'an Pang , Guangyin Jing , Xiaoqiang Feng , Kaige Wang , Wei Zhao

The functional renormalisation group is used for the BCS-BEC crossover in gases of ultracold fermionic atoms. In a simple truncation, we see how universality and an effective theory with composite bosonic di-atom states emerge. We obtain a…

超导电性 · 物理学 2009-11-13 S. Diehl , H. Gies , J. M. Pawlowski , C. Wetterich

Whilst grading neurovascular abnormalities is critical for prompt surgical repair, no statistical markers are currently available for predicting the risk of adverse events, such as stroke, and the overall resilience of a network to vascular…