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Viruses are known to tolerate wide ranges of pH and salt conditions and to withstand internal pressures as high as 100 atmospheres. In this paper we investigate the mechanical properties of viral capsids, calling explicit attention to the…

软凝聚态物质 · 物理学 2009-11-11 Roya Zandi , David Reguera

Colloidal particles can self-assemble into various ordered structures in fluid flows that have potential applications in biomedicine, materials synthesis and encryption. These dynamic processes are also of fundamental interest for probing…

软凝聚态物质 · 物理学 2017-01-31 Yu Abe , Bo Zhang , Leonardo Gordillo , Alireza Mohammad Karim , Lorraine F. Francis , Xiang Cheng

Nanoparticles introduced in living cells are capable of strongly promoting the aggregation of peptides and proteins. We use here molecular dynamics simulations to characterise in detail the process by which nanoparticle surfaces catalyse…

生物大分子 · 定量生物学 2010-06-08 Stefan Auer , Antonio Trovato , Michele Vendruscolo

The inverse problem of designing component interactions to target emergent structure is fundamental to numerous applications in biotechnology, materials science, and statistical physics. Equally important is the inverse problem of designing…

计算物理 · 物理学 2020-11-20 Carl P. Goodrich , Ella M. King , Samuel S. Schoenholz , Ekin D. Cubuk , Michael Brenner

Multipartite viruses replicate through a puzzling evolutionary strategy. Their genome is segmented into two or more parts, and encapsidated in separate particles that appear to propagate independently. Completing the replication cycle,…

物理与社会 · 物理学 2019-03-26 Eugenio Valdano , Susanna Manrubia , Sergio Gómez , Alex Arenas

We systematically investigate the self-assembly of anisotropic cone-shaped particles decorated by ring-like attractive patches. We demonstrate that the self-assembled clusters, which arise due to the conical particle's anisotropic shape…

材料科学 · 物理学 2007-05-23 Ting Chen , Zhenli Zhang , Sharon C. Glotzer

Self-assembly kinetics is usually described by approaches which assume that the shape of the aggregates has a definite form (e.g., spherical, cylindrical, cubic, etc), however that is unlikely to be the case in many finite-sized…

软凝聚态物质 · 物理学 2022-07-13 L. F. Trugilho , L. G. Rizzi

Block copolymer self-assembly is a fundamental process in which incompatible blocks spontaneously form organized microstructures with broad practical applications. Classical understanding is that the domain spacing is limited by the contour…

软凝聚态物质 · 物理学 2022-06-28 Shifeng Nian , Zhouhao Fan , Guillaume Freychet , Mikhail Zhernenkov , Stefanie Redemann , Li-Heng Cai

This review article discusses some common enhanced sampling methods in relation to the process of self-assembly of biomolecules. An introduction to self-assembly and its challenges is covered followed by a brief overview of the methods and…

软凝聚态物质 · 物理学 2025-03-03 Mason Hooten , Het Patel , Yiwei Shao , Rishabh Kumar Singh , Meenakshi Dutt

The algorithmic self-assembly of shapes has been considered in several models of self-assembly. For the problem of \emph{shape construction}, we consider an extended version of the Two-Handed Tile Assembly Model (2HAM), which contains…

计算几何 · 计算机科学 2016-08-18 Austin Luchsinger , Robert Schweller , Tim Wylie

The possibility to align and organize faceted particles in the bulk offers intriguing possibilities for the design and discovery of materials and architectures exhibiting novel functional properties. The growth of ice crystals can be used…

材料科学 · 物理学 2015-07-01 Florian Bouville , Eric Maire , Sylvain Deville

Understanding how highly symmetric, robust, monodisperse protein cages self-assemble can have major applications in various areas of bio-nanotechnology, such as drug delivery, biomedical imaging and gene therapy. We develop a model to…

软凝聚态物质 · 物理学 2018-09-11 Sanaz Panahandeh , Siyu Li , Roya Zandi

The evolution of multicellular organisms from monocellular ancestors represents one of the greatest advances of the history of life. The assembly of such multicellular organisms requires signalling and response between cells: over millions…

细胞行为 · 定量生物学 2007-05-23 Graeme J. Ackland , Richard D. L. Hanes , Morrel H. Cohen

Anisotropy at the level of the inter-particle interaction provides the particles with specific instructions for the self-assembly of target structures. The ability to synthesize non-spherical colloids, together with the possibility of…

软凝聚态物质 · 物理学 2020-01-03 Carina Karner , Christoph Dellago , Emanuela Bianchi

Human immunodeficiency virus (HIV) capsid proteins spontaneously assemble around the genome into a protective protein shell called the capsid, which can take on a variety of shapes broadly classified as conical, cylindrical and irregular.…

生物物理 · 物理学 2016-08-10 Gonca Erdemci-Tandogan , Jef Wagner , Paul van der Schoot , Roya Zandi

From dumbbells to FCC crystals, we study the self-assembly pathway of amphiphatic, spherical colloidal particles as a function of the size of the hydrophobic region using molecular dynamics simulations. Specifically, we analyze how local…

软凝聚态物质 · 物理学 2015-05-13 William L. Miller , Angelo Cacciuto

Polypeptides can self-assemble into hierarchically organized fibrils consisting of a stack of individually folded polypeptides driven together by hydrophobic interaction. Using a coarse grained model, we systematically studied this…

软凝聚态物质 · 物理学 2013-07-31 Ran Ni , Sanne Abeln , Marieke Schor , Martien A. Cohen Stuart , Peter G. Bolhuis

We show systematically that a steady-state ensemble of mesoscopic inclusions of a solute-rich fluid can emerge in liquid solutions well outside the region of stability of the solute-rich phase. Unanticipated by conventional treatments, this…

软凝聚态物质 · 物理学 2019-06-19 Ho Yin Chan , Vassiliy Lubchenko

The self-assembly of submerged cold-plasma-treated polyethylene beads is reported. The plasma-treated immersed millimetrically-sized polyethylene beads formed well-ordered 2D quasi-crystalline structures. The submerged floating of light…

We explore the self-assembly process of colloidal structures immersed in active baths. By considering low-valence particles we numerically investigate the irreversible aggregation dynamics originated by the presence of run-and-tumble…

软凝聚态物质 · 物理学 2019-01-30 Luca Angelani