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Unlike other tissue types, like epithelial tissue, which consist of cells with a much more homogeneous structure and function, the nervous tissue spans in a complex multilayer environment whose topographical features display a large…

生物物理 · 物理学 2017-05-12 C. Simitzi , A. Ranella , E. Stratakis

Many mathematical models of synaptic plasticity have been proposed to explain the diversity of plasticity phenomena observed in biological organisms. These models range from simple interpretations of Hebb's postulate, which suggests that…

神经元与认知 · 定量生物学 2025-08-05 Danil Tyulmankov

The spiking activity of principal cells in mammalian hippocampus encodes an internalized neuronal representation of the ambient space---a cognitive map. Once learned, such a map enables the animal to navigate a given environment for a long…

神经元与认知 · 定量生物学 2017-10-10 Andrey Babichev , Dmitriy Morozov , Yuri Dabaghian

The structure and dynamics of a molecular system is governed by its potential energy surface (PES), representing the total energy as a function of the nuclear coordinates. Obtaining accurate potential energy surfaces is limited by the…

化学物理 · 物理学 2023-09-29 Karl P. Horn , Luis Itza Vazquez-Salazar , Christiane P. Koch , Markus Meuwly

Functional brain connectivity changes dynamically over time, making its representation challenging for learning on non-Euclidean data. We present a framework that encodes dynamic functional connectivity as an image representation of…

神经元与认知 · 定量生物学 2025-11-14 Peilin He , Tananun Songdechakraiwut

Lifelong learning and adaptability are two defining aspects of biological agents. Modern reinforcement learning (RL) approaches have shown significant progress in solving complex tasks, however once training is concluded, the found…

神经与进化计算 · 计算机科学 2022-04-20 Elias Najarro , Sebastian Risi

To compensate for sensory processing delays, the visual system must make predictions to ensure timely and appropriate behaviors. Recent work has found predictive information about the stimulus in neural populations early in vision…

神经元与认知 · 定量生物学 2018-10-05 Audrey J. Sederberg , Jason N. MacLean , Stephanie E. Palmer

In the absence of environmental cues, a migrating cell performs an isotropic random motion. Recently, the breaking of this isotropy has been observed when cells move in the presence of asymmetric adhesive patterns. However, up to now the…

软凝聚态物质 · 物理学 2015-06-17 M. Le Berre , Yan-Jun Liu , J. Hu , P. Maiuri , O. Bénichou , R. Voituriez , Y. Chen , M. Piel

Using miniscope recordings of calcium fluorescence signals in the CA1 region of the hippocampus of mice, we monitor the neural activity of hippocampal regions while the animals are freely moving in an open chamber. Using a data-driven…

神经元与认知 · 定量生物学 2022-04-06 Yi-Ling Chen , Chun-Chung Chen , Yu-Ying Mei , Ning Zhou , Dongchuan Wu , Ting-Kuo Lee

In many developmental systems, cells differentiate into a tissue by reading out morphogen concentration fields, a process fundamentally limited by noise. How much can the precision of this process be improved by nonlocal information, e.g.,…

生物物理 · 物理学 2025-12-24 Alex Chen Yi Zhang , Pablo Mateu Hoyos , David Brückner , Gašper Tkačik

We perform a stationary state replica analysis for a layered network of Ising spin neurons, with recurrent Hebbian interactions within each layer, in combination with strictly feed-forward Hebbian interactions between successive layers.…

凝聚态物理 · 物理学 2009-10-28 A. C. C. Coolen , L. Viana

Neuronal function requires precise spatial organization of mitochondria to meet localized energetic demand. However, the physical constraints governing mitochondrial transport in axons remain poorly defined. Bidirectional motor-driven…

生物物理 · 物理学 2026-04-27 Patrick S. Noerr , Ahmed A. Abushawish , Gulcin Pekkurnaz , Padmini Rangamani

The architecture of iso-orientation domains in the primary visual cortex of placental carnivores and primates apparently follows species invariant quantitative laws. Dynamical optimization models assuming that neurons coordinate their…

神经元与认知 · 定量生物学 2015-12-01 Manuel Schottdorf , Wolfgang Keil , David Coppola , Leonard E. White , Fred Wolf

Lateral inhibition models coupled with Hebbian plasticity have been shown to learn factorised causal representations of input stimuli, for instance, oriented edges are learned from natural images. Currently, these models require the…

神经元与认知 · 定量生物学 2025-01-07 Henrique Reis Aguiar , Matthias H. Hennig

We consider the information transmission problem in neurons and its possible implications for learning in neural networks. Our approach is based on recent developments in statistical physics and complexity science. Combining sensory…

神经元与认知 · 定量生物学 2025-09-30 Siddharth Kackar

This work studies how brain-inspired neural ensembles equipped with local Hebbian plasticity can perform active inference (AIF) in order to control dynamical agents. A generative model capturing the environment dynamics is learned by a…

神经与进化计算 · 计算机科学 2023-06-23 Ali Safa , Tim Verbelen , Lars Keuninckx , Ilja Ocket , André Bourdoux , Francky Catthoor , Georges Gielen , Gert Cauwenberghs

Synaptic plasticity is widely accepted to be the mechanism behind learning in the brain's neural networks. A central question is how synapses, with access to only local information about the network, can still organize collectively and…

神经与进化计算 · 计算机科学 2019-12-06 Dina Obeid , Hugo Ramambason , Cengiz Pehlevan

Electronic transitions involving core-level orbitals offer a localized, atomic-site and element specific peek window into statistical systems such as molecular liquids. Although formally understood, the complex relation between structure…

化学物理 · 物理学 2022-09-02 Johannes Niskanen , Anton Vladyka , J. Antti Kettunen , Christoph J. Sahle

Even with the advent of more sophisticated, data-hungry methods, boosted decision trees remain extraordinarily successful for fast rigid object detection, achieving top accuracy on numerous datasets. While effective, most boosted detectors…

计算机视觉与模式识别 · 计算机科学 2014-11-05 Woonhyun Nam , Piotr Dollár , Joon Hee Han

The robustness of machine learning models can be compromised by spurious correlations between non-causal features in the input data and target labels. A common way to test for such correlations is to train on data where the label is…

计算机视觉与模式识别 · 计算机科学 2026-04-16 Akshit Achara , Yovin Yathathugoda , Nick Byrne , Michela Antonelli , Esther Puyol Anton , Alexander Hammers , Andrew P. King